Abstract
Study Design
Retrospective cohort.
Objectives
To determine if the use of cell saver reduces overall blood costs in adult spinal deformity (ASD) surgery.
Summary of Background Data
Recent studies have questioned the clinical value of cell saver during spine procedures.
Methods
ASD patients enrolled in a prospective, multicenter surgical database who had complete preoperative and surgical data were identified. Patients were stratified into (1) cell saver available during surgery, but no intraoperative autologous infusion (No Infusion group), or (2) cell saver available and received autologous infusion (Infusion group).
Results
There were 427 patients in the Infusion group and 153 in the No infusion group. Patients in both groups had similar demographics. Mean autologous infusion volume was 698 mL. The Infusion group had a higher percentage of EBL relative to the estimated blood volume (42.2%) than the No Infusion group (19.6%, p < .000). Allogeneic transfusion was more common in the Infusion group (255/427, 60%) than the No Infusion group (67/153, 44%, p = .001). The number of allogeneic blood units transfused was also higher in the Infusion group (2.4) than the No Infusion group (1.7, p = .009).
Total blood costs ranged from $396 to $2,146 in the No Infusion group and from $1,262 to $5,088 in the Infusion group. If the cost of cell saver blood was transformed into costs of allogeneic blood, total blood costs for the Infusion group would range from $840 to $5,418. Thus, cell saver use yielded a mean cost savings ranging from $330 to $422 (allogeneic blood averted). Linear regression showed that after an EBL of 614 mL, cell saver becomes cost-efficient.
Conclusion
Compared to transfusing allogeneic blood, cell saver autologous infusion did not reduce the proportion or the volume of allogeneic transfusion for patients undergoing surgery for adult spinal deformity. The use of cell saver becomes cost-efficient above an EBL of 614 mL, producing a cost savings of $330 to $422.
Level of Evidence
Level III.
Similar content being viewed by others
References
Johnson RG, Murphy M, Miller M. Fusions and transfusions. An analysis of blood loss and autologous replacement during lumbar fusions. Spine 1989;14:358–62.
Nuttall GA, Horlocker TT, Santrach PJ, et al. Predictors of blood transfusions in spinal instrumentation and fusion surgery. Spine 2000;25:596–601.
Canan CE, Myers JA, Owens RK, et al. Blood salvage produces higher total blood product costs in single-level lumbar spine surgery. Spine 2013;38:703–8.
Sharma S, Sharma P, Tyler LN. Transfusion of blood and blood products: indications and complications. Am Fam Physician 2011;83:719–24.
Ashworth A, Klein AA. Cell salvage as part of a blood conservation strategy in anaesthesia. Br J Anaesth 2010;105:401–16.
Waters JH, Dyga RM, Waters JF, et al. The volume of returned red blood cells in a large blood salvage program: where does it all go? Transfusion 2011;51:2126–32.
Weltert L, Nardella S, Rondinelli MB, et al. Reduction of allogeneic red blood cell usage during cardiac surgery by an integrated intra- and postoperative blood salvage strategy: results of a randomized comparison. Transfusion 2013;53:790–7.
Gause PR, Siska PA, Westrick ER, et al. Efficacy of intraoperative cell saver in decreasing postoperative blood transfusions in instrumented posterior lumbar fusion patients. Spine 2008;33:571–5.
Kelly PD, Parker SL, Mendenhall SK, et al. Cost-effectiveness of cell saver in short-segment lumbar laminectomy and fusion (⩽3 levels). Spine 2015;40:E978–85.
Owens 2nd RK, Crawford 3rd CH, Djurasovic M, et al. Predictive factors for the use of autologous cell saver transfusion in lumbar spinal surgery. Spine 2013;38:E217–22.
Reitman CA, Watters 3rd WC, Sassard WR. The Cell Saver in adult lumbar fusion surgery: a cost-benefit outcomes study. Spine 2004;29:1580–3; discussion 4.
Szpalski M, Gunzburg R, Aebi M, et al. Research and evidence about blood sparing in spine surgery. Eur Spine J 2004;13(Suppl 1):S1–2.
Charlson ME, Pompei P, Ales KL, MacKenzie CR. A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987;40:373–83.
Chanda A, Smith DR, Nanda A. Autotransfusion by cell saver technique in surgery of lumbar and thoracic spinal fusion with instrumentation. J Neurosurg 2002;96:298–303.
Author information
Authors and Affiliations
Consortia
Corresponding author
Additional information
Author disclosures
JLG (none); LYC (none); MPK (none); RH (none); Chessie Robinson (none); DCB (none); DWP (none); CIS (none); VL (none); FJS (none); CPA (none); HJK (none); JSS (none); RSB (none).
Rights and permissions
About this article
Cite this article
Gum, J.L., Carreon, L.Y., Kelly, M.P. et al. Cell Saver for Adult Spinal Deformity Surgery Reduces Cost. Spine Deform 5, 272–276 (2017). https://doi.org/10.1016/j.jspd.2017.01.005
Received:
Revised:
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1016/j.jspd.2017.01.005