Abstract
Poor adherence to standard protocols of blood pressure (BP) measurement in routine clinical practice leads to higher readings than “research-quality” measurements. Whether this phenomenon exists in periodic health examinations was unknown. We aimed to explore the concordance between BP measurements in periodic health examinations and those measured following a standard measurement protocol. We used data from the Kailuan Study, an ongoing longitudinal cohort study in China, of which participants received biennial health examinations in health management centers. In addition, BPs were measured following standard protocols in a workplace-based hypertension management program nested in the Kailuan Study. We compared BP readings of the same person between the two settings using generalized linear mixed-effects models. A total of 3988 men (the mean age was 44.9 years) had at least two BP measurements both in health examinations and management program with a time interval between the two settings that less than 90 days. The mean systolic blood pressures (SBP) and diastolic blood pressures (DBP) in health examinations were 4.2 (95% CI 3.9–4.5) mm Hg and 3.3 (95% CI 3.1–3.5) mm Hg higher than those in the management program, respectively. Bland–Altman analyses showed the wide agreement intervals ranging from − 27.7- to 36.5-mm Hg for SBP and − 18.3- to 24.7-mm Hg for DBP. In conclusion, BP measurements in periodic health examinations were generally higher than BPs measured following a standard protocol. Our findings highlight the importance of standard BP measurement to avoid overestimation of hypertension prevalence and treatment initiation.
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Data Availability
The datasets generated during the current study are not publicly available due to data confidentiality but are available from the corresponding author on reasonable request.
References
Bhatt H, Siddiqui M, Judd E, Oparil S, Calhoun D (2016) Prevalence of pseudoresistant hypertension due to inaccurate blood pressure measurement. J Am Soc Hypertens 10(6):493–499. https://doi.org/10.1016/j.jash.2016.03.186
Bland JM, Altman DG (1999) Measuring agreement in method comparison studies. Stat Methods Med Res 8(2):135–160. https://doi.org/10.1177/096228029900800204
Broad J, Wells S, Marshall R, Jackson R (2007) Zero end-digit preference in recorded blood pressure and its impact on classification of patients for pharmacologic management in primary care - PREDICT-CVD-6. Br J Gen Pract 57(544):897–903. https://doi.org/10.3399/096016407782317964
Charap MH (1981) The periodic health examination: genesis of a myth. Ann Intern Med 95(6):733–735. https://doi.org/10.7326/0003-4819-95-6-733
Council on Scientific Affairs (1983) Medical evaluations of healthy persons. J Am Med Assoc 249(12):1626–1633. https://doi.org/10.1001/jama.1983.03330360066040
Drawz P (2017) Clinical implications of different blood pressure measurement techniques. Curr Hypertens Rep 19(7):54. https://doi.org/10.1007/s11906-017-0751-0
Drawz PE, Ix JH (2018) BP measurement in clinical practice: time to SPRINT to guideline-recommended protocols. J Am Soc Nephrol 29(2):383–388. https://doi.org/10.1681/ASN.2017070753
Drawz PE, Agarwal A, Dwyer JP et al (2020) Concordance between blood pressure in the systolic blood pressure intervention trial and in routine clinical practice. JAMA Intern Med 180(12):1655–1663. https://doi.org/10.1001/jamainternmed.2020.5028
Edie EB (1925) Health examinations past and present and their promotion in pennsylvania. Am J Public Health 15(7):602–606. https://doi.org/10.2105/ajph.15.7.602
GBD 2019 Risk factors collaborators (2020) Global burden of 87 risk factors in 204 countries and territories, 1990–2019: a systematic analysis for the Global Burden of Disease Study 2019. Lancet 396(10258):1223–1249. https://doi.org/10.1016/S0140-6736(20)30752-2
Graves JW, Nash C, Burger K, Bailey K, Sheps SG (2003) Clinical decision-making in hypertension using an automated (BpTRU™) measurement device. J Hum Hypertens 17(12):823–827. https://doi.org/10.1038/sj.jhh.1001626
Head GA, Mihailidou AS, Duggan KA et al (2010) Definition of ambulatory blood pressure targets for diagnosis and treatment of hypertension in relation to clinic blood pressure: prospective cohort study. BMJ 340:c1104. https://doi.org/10.1136/bmj.c1104
Jin C, Chen S, Vaidya A et al (2017) Longitudinal change in fasting blood glucose and myocardial infarction risk in a population without diabetes. Diabetes Care 40(11):1565–1572. https://doi.org/10.2337/dc17-0610
Kim ES, Samuels TA, Yeh HC et al (2007) End-digit preference and the quality of blood pressure monitoring in diabetic adults. Diabetes Care 30(8):1959–1963. https://doi.org/10.2337/dc07-0020
Levey AS, Stevens LA, Schmid CH et al (2009) A new equation to estimate glomerular filtration rate. Ann Intern Med 150(9):604–612. https://doi.org/10.7326/0003-4819-150-9-200905050-00006
Lewington S, Clarke R, Qizilbash N, Peto R, Collins R, Prospective Studies Collaboration (2002) Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 360(9349):1903–1913. https://doi.org/10.1016/s0140-6736(02)11911-8
Liss DT, Uchida T, Wilkes CL, Radakrishnan A, Linder JA (2021) General health checks in adult primary care: a review. J Am Med Assoc 325(22):2294–2306. https://doi.org/10.1001/jama.2021.6524
Liu LS, Writing Group of 2010 Chinese guidelines for the management of hypertension (2011) [2010 Chinese guidelines for the management of hypertension]. Zhonghua Xin Xue Guan Bing Za Zhi 39(7):579–615. https://doi.org/10.3760/cma.j.issn.0253-3758.2011.07.002
Minor DS, Butler KR Jr, Artman KL et al (2012) Evaluation of blood pressure measurement and agreement in an academic health sciences center. J Clin Hypertens 14(4):222–227. https://doi.org/10.1111/j.1751-7176.2012.00599.x
Muntner P, Shimbo D, Carey RM et al (2019) Measurement of blood pressure in humans: a scientific statement from the american heart association. Hypertension 73(5):e35–e66. https://doi.org/10.1161/HYP.0000000000000087
Rapsomaniki E, Timmis A, George J et al (2014) Blood pressure and incidence of twelve cardiovascular diseases: lifetime risks, healthy life-years lost, and age-specific associations in 1·25 million people. Lancet 383(9932):1899–1911. https://doi.org/10.1016/S0140-6736(14)60685-1
Ray GM, Nawarskas JJ, Anderson JR (2012) Blood pressure monitoring technique impacts hypertension treatment. J Gen Intern Med 27(6):623–629. https://doi.org/10.1007/s11606-011-1937-9
Siu AL, U.S. Preventive Services Task Force (2015) Screening for high blood pressure in adults: U.S. Preventive services task force recommendation statement. Ann Int Med 163(10):778–786. https://doi.org/10.7326/M15-2223
Takahashi H, Yoshika M, Yokoi T (2015) Validation of two automatic devices for the self-measurement of blood pressure according to the ANSI/AAMI/ISO81060-2:2009 guidelines: the Omron BP765 (HEM-7311-ZSA) and the Omron BP760N (HEM-7320-Z). Vasc Health Risk Manag 11:49–53. https://doi.org/10.2147/VHRM.S72438
Wang C, Yuan Y, Zheng M et al (2020) Association of age of onset of hypertension with cardiovascular diseases and mortality. J Am Coll Cardiol 75(23):2921–2930. https://doi.org/10.1016/j.jacc.2020.04.038
Whelton PK, Carey RM, Aronow WS et al (2018) 2017 ACC/AHA/AAPA/ABC/ACPM/AGS/APhA/ASH/ASPC/NMA/PCNA Guideline for the prevention, detection, evaluation, and management of high blood pressure in adults: a report of the American College of Cardiology/American Heart Association Task Force on Clinical Practice Guidelines. Hypertension 71(6):e13–e115. https://doi.org/10.1161/HYP.0000000000000065
SPRINT Research Group, Wright JT Jr, Williamson JD et al (2015) A randomized trial of intensive versus standard blood-pressure control. N Engl J Med 373(22):2103–2116. https://doi.org/10.1056/NEJMoa1511939
Wu Z, Jin C, Vaidya A et al (2016) Longitudinal patterns of blood pressure, incident cardiovascular events, and all-cause mortality in normotensive diabetic people. Hypertension 68(1):71–77. https://doi.org/10.1161/HYPERTENSIONAHA.116.07381
Zhou YF, Chen S, Wang G et al (2022) Effectiveness of a workplace-based, multicomponent hypertension management program in real-world practice: a propensity-matched analysis. Hypertension 79(1):230–240. https://doi.org/10.1161/HYPERTENSIONAHA.121.18305
Acknowledgements
The authors thank all the survey teams of the Kailuan study group for their contribution and the study participants who contributed their information.
Funding
AP was supported by National Natural Science Foundation of China (81930124 and 82021005) and Shanghai Municipal Science and Technology Major Project (Grant No. 2017SHZDZX01).
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J-XC and Y-FZ contributed equally. Conceptualization: J-XC, Y-FZ, SW and AP; methodology: J-XC and Y-FZ; formal analysis: J-XC; investigation: SC and GW; writing—original draft preparation: J-XC; writing—review and editing: all authors; resources: SW; supervision: SW and AP.
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Chen, JX., Zhou, YF., Geng, T. et al. Low Concordance Between Blood Pressures Measured in Periodic Health Examinations and in a Workplace-Based Hypertension Management Program. Phenomics 2, 419–429 (2022). https://doi.org/10.1007/s43657-022-00067-w
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DOI: https://doi.org/10.1007/s43657-022-00067-w