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Efficacy and Safety of High-Viscosity Bone Cement in Percutaneous Vertebroplasty for Kummell’s Disease

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Abstract

Background

To analyze and evaluate the clinical outcomes of using high-viscosity bone cement compared to low-viscosity bone cement in percutaneous vertebroplasty (PVP) for treatment of Kummell’s disease.

Methods

From July 2017 to July 2019, 68 Kummell’s disease patients who underwent PVP were chosen and separated into 2 groups: H group (n = 34), were treated with high-viscosity bone cement and L group (n = 34), treated with low-viscosity bone cement during treatment. The operation time, number of fluoroscopy tests done, and amount of bone cement perfusion were recorded for both groups. Clinical outcomes were compared, by measuring their Visual Analog Scale (VAS), Oswestry Disability Index (ODI), Kyphosis Cobb’s angle, vertebral height compression rate, and other complications.

Results

High-viscosity group showed less operation time and reduced number of fluoroscopy tests than the low-viscosity group (P < 0.05). When compared to preoperative period, both groups’ VAS and ODI scores were significantly reduced at 1 day and 1 year postoperatively (P < 0.05). The vertebral height compression rate and Cobb’s angle were significantly lower (P < 0.05) in both groups after surgery compared with those before surgery (P < 0.05). The cement leakage rate in group H was 26.5%, which was significantly lower than that in group L, which was 61.8% (P < 0.05).

Conclusions

High-viscosity and low-viscosity bone cement in PVP have similar clinical efficacy in reducing pain in patients during the treatment, but in contrast, high-viscosity bone cement shortens the operative time, reduces number of fluoroscopy views and vertebral cement leakage and improves surgical safety.

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Data Availability

All information included in this review is documented by relevant references.

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Funding

This research received no external funding.

Author information

Authors and Affiliations

  1. Department of Spine Surgery, The Third Hospital of Hebei Medical University, 139 Ziqiang Road, Shijiazhuang, 050051, China

    Dong-Jie Kan, Lin-Feng Wang & Yong Shen

  2. Department of Spine Surgery, Affiliated Hospital of Hebei University of Engineering, 81 Congtai Road, Handan, 056000, China

    Dong-Jie Kan & Jing-Huai Wang

  3. Department of Urinary Surgery, Affiliated Hospital of Hebei University of Engineering, 81 Congtai Road, Handan, 056000, China

    Dong-Ping Han

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  1. Dong-Jie Kan
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  4. Lin-Feng Wang
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Contributions

Conceptualization, D-JK; Methodology, D-PH; Software, D-PH; Formal analysis, J-HW and L-FW; Investigation, J-HW; Resources, L-FW; Writing—original draft, D-JK; Writing—review and editing, YS; Supervision, YS.

Corresponding author

Correspondence to Yong Shen.

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Conflict of interest

The authors declare no conflict of interest.

Ethical Standard Statement

This article does not contain any studies with human or animal subjects performed by the any of the authors.

Informed Consent Statement

Written informed consent has been obtained from the patient(s) to publish this paper.

Institutional Review Board Statement

The study was conducted according to the guidelines of the Declaration of Helsinki and approved by the Institutional Review Board (or Ethics Committee) of Affiliated Hospital of Hebei University of Engineering (2022[K]038 and 2022-6-16).

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Kan, DJ., Han, DP., Wang, JH. et al. Efficacy and Safety of High-Viscosity Bone Cement in Percutaneous Vertebroplasty for Kummell’s Disease. JOIO 58, 575–586 (2024). https://doi.org/10.1007/s43465-024-01133-3

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  • DOI: https://doi.org/10.1007/s43465-024-01133-3

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