Abstract
The new coronavirus (COVID-19) upsurge continues to grow all around the globe and had killed more than 60 lakh people. This infection can progress into pneumonia which can be identified through chest X-ray (CXR) image investigation. The present diagnostic process uses real-time reverse-transcription polymerase chain reaction (RT-PCR) based detection which is not very sensitive in detecting the virus at the early phase. Therefore, a more powerful and a substitute detection technique is much needed. In this paper, we introduce an automatic COVID-19 infection detection scheme using CXR images. Very few images of people with this infection are openly available due to which the dataset imbalancing and further the overfitting issues may arise. In this work, we used generative adversarial network (GAN) generated synthetic images for the COVID-19, Normal and Pneumonia categories to overcome this issue. We employ various convolutional neural networks (CNNs) such as Resnet50, Vgg-19, Mobilenet-v2, Inception-v3 and Densenet-201 based transfer learning for the purpose of feature extraction from input X-ray images and then these CNNs are combined with machine learning techniques SVM for the COVID-19 infection detection. We exploit the Contrast Limited Adaptive Histogram Equalization(CLAHE) to enhance the contrast-levels of input CXR images. The results demonstrate that the blend of fine-tuned Inception-v3 and Vgg-19 features when fed into the support vector machine (SVM) classifier provides superior results than many other reported techniques for COVID-19 diagnosis. Our technique was able to attain an accuracy of 99.47% in a 3-category classification system, which makes it a promising scheme for diagnosis of COVID-19.
Similar content being viewed by others
Data availability
Data available on request from the authors.
References
Abraham B, Nair SM. Computer-aided detection of Covid-19 from X-ray images using multi-CNN and Bayesnet classifier. Biocybern Biomed Eng. 2020;40:1436–45. https://doi.org/10.1016/j.bbe.2020.08.005.
Aggarwal P, Mishra NK, Fatimah B, et al. Covid-19 image classification using deep learning: advances, challenges and opportunities. Comput Biol Med. 2022;144:105350.
Aggarwal S, Gupta S, Alhudhaif A, et al. Automated Covid-19 detection in chest X-ray images using fine-tuned deep learning architectures. Expert Syst. 2022;39:e12749. https://doi.org/10.1111/exsy.12749.
Ahmadian S, Jalali SMJ, Islam SMS, et al. A novel deep neuroevolution-based image classification method to diagnose coronavirus disease (covid-19). Comput Biol Med. 2021;139(104):994.
Al-falluji RA, Katheeth ZD, Alathari B. Automatic detection of covid-19 using chest X-ray images and modified resnet18-based convolution neural networks. Comput Mater Continua. 2021;66(2):1301–1313.
Albu F, Mateescu A, Dumitriu N. Architecture selection for a multilayer feedforward network. In: International conference on microelectronics and computer science, 1997. p. 131–134.
Albu F, Vertan C, Florea C, et al. One scan shadow compensation and visual enhancement of color images. In: 16th IEEE international conference on image processing (ICIP). Cairo: Egypt; 2009. p. 3133–6.
Barshooi A, Amirkhani A. A novel data augmentation based on gabor filter and convolutional deep learning for improving the classification of covid-19 chest X-ray images. Biomed Signal Process Control. 2021;72(103):326. https://doi.org/10.1016/j.bspc.2021.103326.
Dhiman G, Chang V, Singh KK, et al. Adopt: Automatic deep learning and optimization-based approach for detection of novel coronavirus covid-19 disease using X-ray images. J Biomolecular Struct Dyn. 2021. https://doi.org/10.1080/07391102.2021.1875049.
El Asnaoui K. Design ensemble deep learning model for pneumonia disease classification. Int J Multimed Inf Retrieval. 2021;10(1):55–68.
Gayathri JL, Abraham B, SujaraniM S, et al. A computer-aided diagnosis system for the classification of covid-19 and non-covid-19 pneumonia on chest X-ray images by integrating CNN with sparse autoencoder and feed forward neural network. Comput Biol Med. 2021;141: 105134.
Goel T, Murugan R, Mirjalili S., et al. Automatic screening of covid-19 using an optimized generative adversarial network. Cognitive Comput 2021;1–16.
Gopatoti A, Vijayalakshmi P. X-ray image classification for covid-19 diagnosis using deep CNN with enhanced grey-wolf optimizer. Biomed Signal Process Control. 2022. https://doi.org/10.1016/j.bspc.2022.103860.
Hu C, Sun X, Yuan Z, et al. Classification of breast cancer histopathological image with deep residual learning. Int J Imaging Syst Technol. 2021;31(3):1583–94.
Jain R, Gupta M, Taneja S, et al. Deep learning based detection and analysis of Covid-19 on chest X-ray images. Appl Intell. 2021;51(3):1690–700.
Khalifa NE, Loey M, Mirjalili S. A comprehensive survey of recent trends in deep learning for digital images augmentation. Artif Intell Rev 2021;55:1–27.
Khan AI, Shah JL, Bhat MM. Coronet: a deep neural network for detection and diagnosis of Covid-19 from chest X-ray images. Comput Methods Programs Biomed. 2020;196(105):581.
Kong L, Cheng J. Classification and detection of Covid-19 X-ray images based on densenet and vgg16 feature fusion. Biomed Signal Process Control. 2022;77(103):772.
Loey M, El-Sappagh S, Mirjalili S. Bayesian-based optimized deep learning model to detect covid-19 patients using chest X-ray image data. Comput Biol Med. 2022;142(105):213.
Luz E, Silva P, Pedrosa Silva R, et al. Towards an effective and efficient deep learning model for covid-19 patterns detection in X-ray images. Res Biomed Eng. 2021. https://doi.org/10.1007/s42600-021-00151-6.
Montalbo FJ. Diagnosing Covid-19 chest X-rays with a lightweight truncated densenet with partial layer freezing and feature fusion. Biomed Signal Process Control. 2021;68: 102583. https://doi.org/10.1016/j.bspc.2021.102583.
Narin A, Kaya C, Pamuk Z. Automatic detection of coronavirus disease (covid-19) using X-ray images and deep convolutional neural networks. Pattern Anal Appl. 2021;24(3):1207–20.
Ozturk T, Talo M, Yildirim EA, et al. Automated detection of Covid-19 cases using deep neural networks with x-ray images. Comput Biol Med. 2020;121(103):792.
Panwar H, Gupta P, Siddiqui MK, et al. Application of deep learning for fast detection of Covid-19 in X-rays using ncovnet. Chaos Solitons Fractals. 2020;138(109):944.
Rajpal S, Lakhyani N, Singh A, et al. Using handpicked features in conjunction with resnet-50 for improved detection of Covid-19 from chest X-ray images. Chaos Solitons Fractals. 2021;145(110):749. https://doi.org/10.1016/j.chaos.2021.110749.
Rehman A, Khan S, Harouni M, et al. Brain tumor segmentation using k-means clustering and deep learning with synthetic data augmentation for classification. Microsc Res Tech. 2021;84:1389–99. https://doi.org/10.1002/jemt.23694.
Sait U, Lal KV G, Prakash Prajapati S, Bhaumik R, Kumar T, Shivakumar S, Bhalla K. Curated dataset for COVID-19 posterior–anterior chest radiography images (X-rays). Mendeley Data, V1, 2020.
Salama WM, Aly MH. Framework for Covid-19 segmentation and classification based on deep learning of computed tomography lung images. J Electron Sci Technol. 2022;20(3):100–61.
Shamila Ebenezer A, Deepa Kanmani S, Sivakumar M, et al. Effect of image transformation on efficientnet model for Covid-19 CT image classification. Mater Today Proc. 2022;51:2512–9. https://doi.org/10.1016/j.matpr.2021.12.121.
Sharma A, Singh K, Koundal D. A novel fusion based convolutional neural network approach for classification of Covid-19 from chest X-ray images. Biomed Signal Process Control. 2022;77(103):778. https://doi.org/10.1016/j.bspc.2022.103778.
Sitaula C, Hossain M. Attention-based vgg-16 model for Covid-19 chest X-ray image classification. Appl Intell. 2021;51:1–14. https://doi.org/10.1007/s10489-020-02055-x.
Srivastava G, Chauhan A, Jangid M, et al. Covixnet: a novel and efficient deep learning model for detection of Covid-19 using chest X-ray images. Biomed Signal Process Control. 2022;78(103):848. https://doi.org/10.1016/j.bspc.2022.103848.
Thakur S, Kumar A. X-ray and CT-scan-based automated detection and classification of Covid-19 using convolutional neural networks (CNN). Biomed Signal Process Control. 2021;69(102):920. https://doi.org/10.1016/j.bspc.2021.102920.
Turkoglu M. Covidetectionet: Covid-19 diagnosis system based on X-ray images using features selected from pre-learned deep features ensemble. Appl Intell. 2021;51:1213–26. https://doi.org/10.1007/s10489-020-01888-w.
Yan Q, Wang B, Gong D, et al. Covid-19 chest CT image segmentation network by multi-scale fusion and enhancement operations. IEEE Trans Big Data. 2021;7(1):13–24. https://doi.org/10.1109/TBDATA.2021.3056564.
Acknowledgements
This work was supported by All India Council for Technical Education (AICTE), Govt. of India, through ADF scheme.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Conflict of interest
We have no conflicts of interest to disclose.
Additional information
Publisher's Note
Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.
This article is part of the topical collection “Enabling Innovative Computational Intelligence Technologies for IOT” guest edited by Omer Rana, Rajiv Misra, Alexander Pfeiffer, Luigi Troiano and Nishtha Kesswani.
Rights and permissions
Springer Nature or its licensor (e.g. a society or other partner) holds exclusive rights to this article under a publishing agreement with the author(s) or other rightsholder(s); author self-archiving of the accepted manuscript version of this article is solely governed by the terms of such publishing agreement and applicable law.
About this article
Cite this article
Mahanta, D., Hazarika, D. & Nath, V.K. Automated Diagnosis of COVID-19 Using Synthetic Chest X-Ray Images from Generative Adversarial Networks and Blend of Inception-v3 and Vgg-19 Features. SN COMPUT. SCI. 4, 558 (2023). https://doi.org/10.1007/s42979-023-02002-w
Received:
Accepted:
Published:
DOI: https://doi.org/10.1007/s42979-023-02002-w