Abstract
Background
Neonatal hydrops of the gall bladder is a rare entity, resolving conservatively most of the times, with requirement of surgery only in few cases. It is usually seen in association with septicemia, jaundice, and inborn errors of metabolism. Diagnostic laparoscopy happens to be a useful tool in guiding the management of these babies.
Clinical description
Case 1: A 12-day-old neonate presented with refusal to feeds, jaundice, and right upper abdominal mass. Serum ferritin was markedly raised. Radiological work-up revealed a distended gall bladder and on MRI, there were diffuse hypo-intensities in the liver suggestive of iron deposition. A diagnostic laparoscopy was performed which was suggestive of an over-distended, tense, and shiny gall bladder with normal biliary tree and hepatomegaly. In view of clinical deterioration and large liver, an exploratory laparotomy with cholecystectomy and liver biopsy was performed. Histopathology revealed non-inflamed gall bladder and showed iron overload in the liver biopsy. Case 2: A 2-month-old baby presented with jaundice, clay-colored stool, abdominal distension, and a palpable mass. Sonography and MRCP were suggestive of distended gall bladder with patent distal CBD and dilated IHBR. Serum GGT was raised. USG-guided aspiration revealed white clear transparent fluid. A diagnostic laparoscopy was performed and showed atretic biliary tree with cirrhotic liver and massively distended gall bladder. As the laparoscopic findings were consistent with the biliary atresia, an exploratory laparotomy and Kasai’s portoenterostomy were performed.
Conclusion
Neonatal hydrops usually is secondary to underlying medical or surgical conditions. Apart from medical conditions, rarely it can also occur secondary to neonatal hemosiderosis as seen in gestational alloimmune liver disease and biliary atresia. We thought of proceeding for diagnostic laparoscopy to confirm the rare association before embarking upon the definitive repair.
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References
McEachern CG, Sullivan RE, Arata JE (1955) Massive hydrops of the gallbladder in a five-year-old girl. Ann Surg 142:1038
Bowen A (1984) Acute gallbladder dilatation in a neonate: emphasis on ultrasonography. J Pediatr Gastroenterol Nutr 3:304–308
Appleby GA, Forestier E, Starck CJ (1981) Hydrops of the gallbladder in the neonatal period. Acta Paediatr 70:117–120
Whitington PF (2012) Gestational alloimmune liver disease and neonatal hemochromatosis. Sem Liver Dis 32:325–332
Scobie WG, Bentley JF (1969) Hydrops of the gallbladder in a newborn infant. J Pediatr Surg 4:457–459
Crankson S, Nazer H, Jacobsson B (1992) Acute hydrops of the gallbladder in childhood. Eur J Pediatr 151:318–320
Milch H (1926) Hydrops of the gall-bladder in an infant. Ann Surg 84:415
Bloom RA, Swain VA (1966) Non-calculous distension of the gall-bladder in childhood. Arch Dis Child 41:503
Narat JD (1940) Hydrops of the gallbladder in a 4- year-old child. Am J Surg 49:513
Yoo JH, Kwak HJ, Lee MJ, Suh JS, Rhee CS (2003) Sonographic measurements of normal gallbladder sizes in children. J Clin Ultrasound 31:80–84
Darouich S, Boujelbène N, Amraoui J, Amraoui N, Masmoudi A (2019) Hemochromatosis associated with cholelithiasis as a cause of hydrops fetalis and stillbirth: prenatal diagnosis. J Clin Ultrasound 47:47–50
Shirota C, Hinoki A, Tainaka T, Sumida W, Kinoshita F, Yokota K, Makita S, Amano H, Nakagawa Y, Uchida H (2022) Laparoscopic Kasai portoenterostomy can be a standard surgical procedure for treatment of biliary atresia. World J Gastrointest Surg 14:56
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Prajapati, S., Mittal, P., Ramrakhiani, D. et al. Role of diagnostic laparoscopy in the management of neonatal hydrops of the gall bladder: a report on two rare cases. J Ped Endosc Surg 5, 159–163 (2023). https://doi.org/10.1007/s42804-023-00195-8
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DOI: https://doi.org/10.1007/s42804-023-00195-8