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Pedunculated Cutaneous Neurofibroma: a Case Report and Literature Review

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Abstract

Pedunculated skin lesions frequently appear as peculiar morphologies of varying sizes and locations. These lesions are rare but have many forms. Some lesions have not been fully described and can be confusing. The pedunculated lesion pattern is a subcategory of all cutaneous neurofibroma types. Sporadic pedunculated lesions are often the result of mutations in the neurofibromin 1 of certain cells. We report a case of pedunculated neurofibroma of the left thigh in an adult woman. The lesion was treated surgically without complications. The issue of diagnosis and management of cutaneous neurofibroma is under active research. Through this case, we also update the literature on issues related to cutaneous neurofibroma. Current research directions include planning to establish new classification systems, devising suitable diagnostic methods, and developing optimal therapeutics based on molecular biology, gene therapy, and stem cells.

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Authors and Affiliations

  1. Department of Radiology, Thien Hanh Hospital, 17 Nguyen Chi Thanh Street, Buon Ma Thuot, 630000, Vietnam

    Van Trung Hoang, The Huan Hoang & Hoang Anh Thi Van

  2. Department of Radiology, Nguyen Tri Phuong Hospital, Ho Chi Minh City, Vietnam

    Ny Ny Thi Le

  3. Department of Pathology, University Medical Center at Ho Chi Minh City, Ho Chi Minh City, Vietnam

    Minh Huy Le

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  1. Van Trung Hoang
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  2. The Huan Hoang
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Contributions

VTH, THH, and MHL collected the data and wrote the manuscript. HATV and NNTL reviewed and revised the manuscript. All authors have read and approved the final manuscript.

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Correspondence to Van Trung Hoang.

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Hoang, V.T., Hoang, T.H., Van, H.A.T. et al. Pedunculated Cutaneous Neurofibroma: a Case Report and Literature Review. SN Compr. Clin. Med. 5, 153 (2023). https://doi.org/10.1007/s42399-023-01494-0

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