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Focal Liver Lesions in a Child with Idiopathic Hypereosinophilic Syndrome: an Unusual Finding

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Abstract

Idiopathic hypereosinophilic syndrome (IHES) is characterized by the triad of peripheral blood eosinophilia (> 1500 cells/μl) for more than 6 months, without any other discernible cause of eosinophilia in association with signs and symptoms of organ infiltration related to eosinophilia. IHES is usually seen in the middle age group of 20–50 years and is uncommon in the pediatric population. Herein, we report a case of a 12-year-old male child with IHES who had multi-system involvement (hepatic, pulmonary, and cardiac). The child showed symptomatic, biochemical, and radiological improvement with steroid therapy on follow-up.

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The datasets used and/or analyzed during the current study are available from the corresponding author upon reasonable request.

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References

  1. Leru PM. Eosinophilic disorders: evaluation of current classification and diagnostic criteria, the proposal of a practical diagnostic algorithm. Clin Transl Allergy. 2019;9(1):1–9.

    Article  Google Scholar 

  2. Nam KJ, Jung WJ, Choi JC, Koo BS, Park BH, Lee KN, Han SY, Shin WW, Han SS. Hepatic involvement in hypereosinophilia: sonographic findings. J Ultrasound Med. 1999;18(7):475–9.

    Article  CAS  PubMed  Google Scholar 

  3. Inayat F, Hurairah A. Gastrointestinal and hepatic involvement in hypereosinophilic syndrome. Cureus. 2016;8(8).

  4. Dulohery MM, Patel RR, Schneider F, Ryu JH. Lung involvement in hypereosinophilic syndromes. Respir Med. 2011;105(1):114–21.

    Article  PubMed  Google Scholar 

  5. Shatery K, Sayyah A. Idiopathic hypereosinophilic syndrome presenting with liver mass: report of two cases: idiopathic hypereosinophilic syndrome and liver mass. Hepat Mon. 2011;11(2):123–5.

    PubMed  PubMed Central  Google Scholar 

  6. Ran Jung M, Woo Goo H, Sook Hong S, Hyun Yoon C. A Case Report hypereosinophilic syndrome with hepatic involvement in a young child. J Korean Radiol Soc. 2003;49.

  7. Kim GB, Kwon JH, Kang DS. Hypereosinophilic syndrome: imaging findings in patients with hepatic involvement. AJR Am J Roentgenol. 1993;161(3):577–80.

    Article  CAS  PubMed  Google Scholar 

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Acknowledgements

To Pediatric and Pediatric Surgery Department.

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PSH – conception and design of the work, drafting the article, critical revision of the article. SS – literature search, writing the initial draft, and figures. VS – clinical inputs, data collection. PSV – clinical inputs, drafting the article.

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Correspondence to Poonam Sherwani.

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Sherwani, P., Singhal, S., Sharma, V. et al. Focal Liver Lesions in a Child with Idiopathic Hypereosinophilic Syndrome: an Unusual Finding. SN Compr. Clin. Med. 5, 134 (2023). https://doi.org/10.1007/s42399-023-01464-6

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