Abstract
Wasp stings are not uncommon, particularly in the warmer climates, as people tend to spend longer times outside. A 49-year-old healthy gentleman had suffered multiple wasp stings all over his body. At the primary health centre, he was documented to have had flaccid quadriparesis with serum potassium of 2.3 mEq/L. At our institute, we diagnosed distal renal tubular acidosis. With history and investigations, we have excluded the major causes of distal renal tubular acidosis. We concluded that the wasp sting was responsible for distal renal tubular acidosis. The bradykinin contained in the wasp venom inhibits the basolateral 40-pS K + channel activity in the distal convoluted tubules and stimulates potassium excretion.
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References
D’Cruz S, Chauhan S, Singh R, Sachdev A, Lehl S. Wasp sting associated with type 1 renal tubular acidosis. Nephrol Dial Transplant. 2008;23(5):1754–5.
Agarwal V, D’Cruz S, Sachdev A, et al. Quadriparesis following a wasp sting. Ind J Med Sci. 2005;59:118–9.
Kurtzman NA. Disorders of distal acidification. Kidney Int. 1990;38(4):720–7.
Moreno M, Giralt E. Three valuable peptides from bee and wasp venoms for therapeutic and biotechnological use: melittin, apamin and mastoparan. Toxins (Basel). 2015;7(4):1126–50.
Zhang DD, Gao ZX, Vio CP, Xiao Y, Wu P, Zhang H, Guo XW, Meng XX, Gu L, Wang JL, Duan XP, Lin DH, Wang WH, Gu R. Bradykinin stimulates renal Na+ and K+ excretion by inhibiting the K+ channel (Kir41) in the distal convoluted tubule. Hypertension. 2018;72(2):361–9.
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Krishna Priya N, Navya T, Srilakshmi G: primary care takers of the patient. Ram R: faculty treated this patient and main author of the article. Siva Kumar V: one of the authors.
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N, K.P., T, N., G, S. et al. Renal Tubular Acidosis Following Wasp Sting: a Case Report. SN Compr. Clin. Med. 5, 77 (2023). https://doi.org/10.1007/s42399-023-01411-5
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DOI: https://doi.org/10.1007/s42399-023-01411-5