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Erythema Gyratum Repens and Thyroid Cancer: a Case Report

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Abstract

Erythema gyratum repens (EGR) is a paraneoplastic serpiginous dermatosis that is associated with internal malignancy in approximately 80% of patients. Bronchial cancer is the most frequently associated malignancy. Papillary thyroid cancer accounts for 80% of all thyroid cancers. Metastatic thyroid carcinoma usually spreads to local lymph nodes and distant metastases, especially to the skin, are rare. A paraneoplastic syndrome such as dermatomyositis has been described in association with papillary thyroid cancer. We present a 56-year-old woman with a 2-week history of rash on her armpits. With the suspicion of EGR, a skin biopsy was performed, and together with the clinical correlation, a diagnosis of EGR was made. Complementary tests such as blood test, thoracoabdominal radiography, and CT-PET were performed with no alterations in the results. Thyroid ultrasound showed a 2-cm solid nodule and the puncture aspiration result was significant for papillary thyroid cancer. We describe the first case of EGR in a woman that preceded the diagnosis of papillary thyroid cancer. EGR can be mimicked by other dermatoses, so clinicopathologic correlation is essential for a proper diagnosis and treatment.

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Ana Julia García Malinis, Maria Eugenia Lopez, Pilar Puertolas, and Pedro Jesus Agón Banzo have contributed equally to this work, creating all or substantive part of the scientific research and writing. Yolanda Gilaberte, Francisco Queipo, and Dolores Planas have contributed in the image processing, field work, and providing approval of the final version to be published.

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Correspondence to Ana Julia García-Malinis.

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García-Malinis, A.J., Valverde, M.E.L., Queipo, F. et al. Erythema Gyratum Repens and Thyroid Cancer: a Case Report. SN Compr. Clin. Med. 5, 32 (2023). https://doi.org/10.1007/s42399-022-01372-1

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