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Typical Scurvy in an Atypical Patient: Case Report

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Abstract

Vitamin C deficiency, also known as scurvy, is oftentimes considered a disease of only historic relevance. Our case report demonstrates that scurvy is still prevalent, and can arise in unexpected populations, such as college-aged individuals with imbalanced diets. This case study aims to report the clinical findings and treatment of a 19 year-old male college student diagnosed with scurvy. A thorough history was obtained from the patient, followed by a physical exam. The diagnosis of scurvy was made clinically and confirmed by additional laboratory testing of vitamin C levels. Treatment consisted of a daily over-the-counter vitamin C supplement and multivitamin, as well as nutritional counseling on consumption of adequate fruits and vegetables. The patient presented with scattered erythematous to light-brown eczematous patches, papules, and plaques on the trunk; perifollicular, erythematous, non-blanchable macules on bilateral lower extremities; and bilateral pedal edema. Serology for human immunodeficiency virus, syphilis, cytomegalovirus, Epstein-Barr virus, and Lyme disease was negative. Complete blood counts and a comprehensive metabolic panel were within normal limits except for mild leukopenia. Vitamin C level was < 0.1 mg/dL, with a reference range of 0.2–0.4 mg/dL. The patient began supplementing 1000 mg of vitamin C daily and introducing fruits and vegetables into his diet. Within 2 weeks, he reported remission of most major symptoms. Results are from one individual alone; therefore, there is a lack of generalizability, and caution should be taken with interpretation of these findings. This case exemplifies the importance of maintaining a high clinical suspicion of nutritional deficiencies, such as scurvy, even when a patient’s demographics are not typical for such conditions.

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Abbreviations

AD:

Atopic dermatitis

CMV:

Cytomegalovirus

EBV:

Epstein-Barr virus

HIV:

Human immunodeficiency virus

US:

United States

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Authors

Contributions

All authors contributed equally to the drafting and revision of this manuscript.

Corresponding author

Correspondence to Rima I. Ghamrawi.

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Informed consent was obtained from the patient for publication of the article, including publication of clinical photographs.

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Not applicable.

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Informed consent was obtained from the patient for publication of the article, including publication of clinical photographs.

Competing Interests

Dr. Steven Feldman has received research, speaking, and/or consulting support from a variety of companies including Galderma, GSK/Stiefel, Almirall, Leo Pharma, Boehringer Ingelheim, Mylan, Celgene, Pfizer, Valeant, Abbvie, Samsung, Janssen, Lilly, Menlo, Merck, Novartis, Regeneron, Sanofi, Novan, Qurient, National Biological Corporation, Caremark, Advance Medical, Sun Pharma, Suncare Research, Informa, UpToDate, and National Psoriasis Foundation. He is founder and majority owner of www.DrScore.com and founder and part owner of Causa Research, a company dedicated to enhancing patients’ adherence to treatment. The remaining authors declare no competing interests.

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This case report has not been published previously and is not under consideration for publication elsewhere. A version of this case report was presented as a poster at the 2020 North Carolina Dermatology Association Conference in Raleigh, NC

This article is part of the Topical Collection on Medicine

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Mendes, J.T., Levin, N.J., Ghamrawi, R.I. et al. Typical Scurvy in an Atypical Patient: Case Report. SN Compr. Clin. Med. 4, 80 (2022). https://doi.org/10.1007/s42399-022-01163-8

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  • DOI: https://doi.org/10.1007/s42399-022-01163-8

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