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Flail Mitral Valve Associated with Iliac Artery Aneurysm: Diagnostic Challenges of a Potential Syndromic Pattern. Case Report

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Abstract

Severe mitral valve regurgitation can be caused by a spectrum of disorders that can influence the management of this entity. Here we describe the diagnostic work-up in the case of a patient presenting with flail mitral valve secondary to Barlow’s disease and concomitant fever, underscoring the difficulty in providing differential diagnosis of the underlying causative etiology and to plan subsequent appropriate treatment. Diagnostic tests leaded to the incidental discovery of concomitant iliac artery aneurysm; hence, we discuss the association between Barlow’s disease and arterial abnormalities, possibly pointing towards a syndromic pattern related to common pathogenic background affecting connective tissue.

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Authors and Affiliations

  1. Internal Medicine Unit, Residency Training Program in Internal Medicine, Sapienza University of Rome, Rome, Italy

    Michelangelo Luciani, Piera Amoriello Lamberti, Ludovica Guerritore, Maria Letizia Speranza, Valerio Spuntarelli & Enrico Bentivegna

  2. Sant’Andrea Hospital, Via di Grottarossa, 1035, Rome, Italy

    Michelangelo Luciani

  3. Cardiology, Clinical and Molecular Medicine Department, Faculty of Medicine and Psychology, Sapienza University of Rome, Rome, Italy

    Luca Arcari & Giuseppino Massimo Ciavarella

  4. Emergency Medicine Unit, Azienda Ospedaliera Sant’Andrea, Via di Grottarossa, 1035, Rome, Italy

    Alberto Sentimentale

  5. Department of Clinical and Molecular Medicine, Sapienza University of Rome, Rome, Italy

    Paolo Martelletti

Authors
  1. Michelangelo Luciani
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  2. Luca Arcari
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  3. Piera Amoriello Lamberti
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  4. Ludovica Guerritore
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  5. Maria Letizia Speranza
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  6. Valerio Spuntarelli
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  7. Enrico Bentivegna
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  8. Alberto Sentimentale
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  9. Giuseppino Massimo Ciavarella
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  10. Paolo Martelletti
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Contributions

All authors materially participated in the research. ML, LA, AS, ALP, LG, MLS, and VS participated in data collection, study design, and in article preparation. PM and GMC participated in the conception and final discussion of the manuscript.

All authors have approved the final article.

Paolo Martelletti is the guarantor.

Corresponding author

Correspondence to Michelangelo Luciani.

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The authors declare that they have no conflict of interest.

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Written informed consent was obtained from the patient for publication of this case report and accompanying images.

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Luciani, M., Arcari, L., Lamberti, P.A. et al. Flail Mitral Valve Associated with Iliac Artery Aneurysm: Diagnostic Challenges of a Potential Syndromic Pattern. Case Report. SN Compr. Clin. Med. 2, 481–484 (2020). https://doi.org/10.1007/s42399-020-00254-8

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  • DOI: https://doi.org/10.1007/s42399-020-00254-8

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