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Heavy Metal Accumulation and Health Risk Assessment in Moringa Oleifera from Awi Zone, Ethiopia

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Abstract

Moringa oleifera is rich in minerals and medicinally important tree species of family Moringaceae. In this study the concentration of selected heavy metals (cadmium, copper, chromium, lead and zinc) in Moringa oleifera leaves collected from Guangua and Zigem woredas in Awi Zone, Ethiopia using ICP-OES. The concentrations of metals in Moringa oleifera at Guangua and Zigem were found to be 9.0 and 4.35 mg/kg for Cr, 8.7 and 7.1 mg/kg for Cu and 56.7 and 28.8 mg/kg for Zn, respectively. However, the concentrations of Pb and Cd in all samples were below the detection limit. The concentration of Cu in Guangua and Zigem; and Zn in Zigem were below the permissible limit recommended by WHO. However, the concentration of Cr in both Guangua and Zigem; and Zn in Guangua were found above the permissible limit set by WHO. The validity of the optimized digested procedure was evaluated by spiking the digested samples with standard solution of metals and the percentage recoveries were found in the range 95.8 to 110.0%. The THQ values of Cr were found > 1, indicating that the consumption of Moringa oleifera may cause possible non-carcinogenic health risk. The values health index (HI) were of 9.866 and 4.882 at Guangua and Zigem, respectively, clearly suggests the possible adverse health effect to adult population from the consumption of Moringa oleifera the study areas.

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References

  1. Upta S, Jain R, Kachhwaha S, Kothari L (2018) Nutritional and medicinal applications of Moringa oleifera Lam.-Review of current status and future possibilities. J Herbal Med 11:1–11

    Article  Google Scholar 

  2. Gopalakrishnan L, Doriya K, Kuma D (2016) Moringa oleifera: a review on nutritive importance and its medicinal application. Food Sci Human Wellness 5:49–56

    Article  Google Scholar 

  3. Kassay B, Hailay K (2014) Determination of trace metals (Mn, Cu and Ni) content in Moringa Oliefera using atomic absorption spectroscopy. J Bio Agri Healthcare 4:52–55

    Google Scholar 

  4. Garima M, Pradeep S, Ramesh V, Sunil K, Saurabh S (2011) Traditional uses, phytochemistry and pharmacological properties of Moringa oleifera plant: An overview. Der Pharmacia Lett 3:141–164

    Google Scholar 

  5. Kanitta J, Wannee J (2016) Moringa oleifera a new challenge reducing heavy metal toxicity. Indian J Agri Res 50:199–205

    Google Scholar 

  6. Calderon P, Saguilán A, Cruz A, Carrillo-Ahumad J, Hernandez-Uribe J, Acevedo-Tello S, Torruco-Uco J (2019) Tortilla added with Moringa oleífera flour: physicochemical, texture properties and antioxidant capacity. LWT - Food Sci Techno 100:409–415

    Article  Google Scholar 

  7. Agboola O, Orji D, Olatunji A, Olowoyo J (2016) Bioaccumulation of heavy metals by Moringa Oleifera in automobile workshops from three selected local governments area, Ibadan, Nigeria. West Afr J App Ecol 24:9–18

    Google Scholar 

  8. Tiloke C, Anand K, Gengan R, Chuturgoon A (2018) Moringa oleifera and their phytonanoparticles: Potential antiproliferative agents against cancer. Biomed Pharmacother 108:457–466

    Article  CAS  Google Scholar 

  9. Birendra K, Hemant K, Dhongade B (2017) Phytochemistry and pharmacology of Moringa oleifera lami. J Pharmacopuncture 20:194–200

    Article  Google Scholar 

  10. Ganatra T, Joshi U, Bhalodia P, Desai T, Tirgar P (2012) A panoramic view on pharmacognostic, pharmacological, nutritional, therapeutic and prophylactic values of Moringa oleifera Lam. Int Res J Pharm 3:1–7

    Google Scholar 

  11. Farjana N, Zahangir A, Habibur R, Ekramul H (2003) In vitro antimicrobial activity of the compound isolated from chloroform Extract of Moringa oleifera lam. Pak J Biol Sci 66:1888–1890

    Google Scholar 

  12. Fozia F, Meenu R, Avinash T, Abdul A, Shaila F (2012) Medicinal properties of Moringa oleifera an overview of promising healer. J Med Plants Res 6:4368–4374

    Google Scholar 

  13. Charoensin S (2014) Antioxidant and anticancer activities of Moringa oleifera leaves. J Med Plant Res 8:318–325

    Article  Google Scholar 

  14. Vikashni N, Matakite M, Kanayathu K, Subramanium S (2012) Water purification using Moringa oleifera and other locally available seeds in fiji for heavy metal removal. Int J Appl Sci Technol 2:125–129

    Google Scholar 

  15. Umeh C, Asegbeloyin J, Akpomie K, Oyeka E, Ochonogor A (2020) Adsorption properties of tropical soils from Awka north Anambra Nigeria for lead and cadmium ions from aqueous media. Chem Afr 3:199–210

    Article  CAS  Google Scholar 

  16. Ogunfowokan A, Adekunle A, Oyebode B, Oyekunle J, Komolafe A, Omoniyi-Esan G (2019) Determination of heavy metals in urine of patients and tissue of corpses by atomic absorption spectroscopy. Chem Africa 2:699–712

    Article  CAS  Google Scholar 

  17. Jaya G, Amit G, Gupta A (2014) Determination of trace metals in the stem bark of Moringa oleifera Lam. Int J Chem Stud 2:39–42

    Google Scholar 

  18. Patel A, Prasavna S, Shastry C (2012) Aulcergonic activity of Moringa oleifera root extracts agains ethaool gastric ulcer rats. Int J Pharmaceutical Chem Sci 1:243–249

    Google Scholar 

  19. Fowotade S, Abdallah S (2012) Determination of trace metals in Moringa oleifera (Drumstick) in kazaure Township, Jigawa State of Nigeria. J Phys Sci Inno 4:1–4

    Google Scholar 

  20. Fakankun O, Babayemi J, Utiaruk J (2013) Variations in the mineral composition and heavy metals content of Moringa oleifera. Afr J Environ Sci Technol 7:372–379

    Article  Google Scholar 

  21. Ghosh S, Prasanna L, Sowjanya B, Srivani P, Alagaraja M, Banji D (2013) Inductively coupled plasma: optical emission spectroscopy. Asian J Pharm Ana 3:24–33

    Google Scholar 

  22. Kumaravel S, Alagusundaram K (2014) Determination of mineral content in indian spices by ICP-OES. Ori J Chem 30:631–636

    Article  CAS  Google Scholar 

  23. Griepink B, Tolg G (1998) Sample digestion for the determination of elemental traces in matrices of environmental concerns. Pure Appl Chem 61:1139–1146

    Article  Google Scholar 

  24. Urga K, Narasimha H (1997) Effect of Natural fermentation on the HCl extractability of minerals from tef (Eragrostis tef). Bull Chem Soci Ethiop 11:3–10

    CAS  Google Scholar 

  25. Sharafi K, Nodehi R, Mahvi A, Pirsaheb M, Nazmara S, Mahmoudi B, Yunesian M (2019) Bioaccessibility analysis of toxic metals in consumed rice through an in vitro human digestion model: comparison of calculated human health risk from raw, cooked and digested rice. Food Chem 299:125–136

    Article  Google Scholar 

  26. Miller J (2000) Statistics and chemo metrics for analytical chemistry, 4th edn. Prentice Hall, Harlow, England, pp 60–122

  27. Woldetsadik D, Drechsel P, Keraita B, Itanna F, Gebrekidan H (2017) Heavy metal accumulation and health risk assessment in wastewater-irrigated urban vegetable farming sites of Addis Ababa, Ethiopia. Int J Food Contam 4:1–13

    Article  Google Scholar 

  28. USEPA IRIS (2006) United States. Environmental Protection Agency, Integrated Risk Information System

    Google Scholar 

  29. Kamunda C, Mathuthu M, Madhuku M (2016) Health risk assessment of heavy metals in soils from witwatersrand gold mining basin, South Africa. Int J Environ Res Public Health 13:1–11

    Google Scholar 

  30. Khan S, Farooq R, Shahbaz S, Khan M, Sadique M (2009) Health risk assessment of heavy metals for population via consumption of vegetables. World Appl Sci J 6:1602–1606

    CAS  Google Scholar 

  31. Wioletta B, Anna J, Ewelina Ł (2017) Nutritional quality and safety of Moringa (Moringa oleifera lam., 1785) leaves as an alternative source of protein and minerals. J Elem 22:569–579

    Google Scholar 

  32. Abdulkadir A, Abdu D, Ibrahim H, Abdullahi A (2016) Assessment of heavy metals from the roots, barks and leaves of some selected medicinal plants (Moringa oleifera and Azadirachta indica) grown in kashere metropolis. Int J Sci Eng Appl Sci 2:124–136

    Google Scholar 

  33. Valdez-Solana M, Mejia-Garcia V, Tellez-Valencia A, Garcia-Arenas G, Salas-Pacheco J, Alba-Romero J (2015) Nutritional content and elemental and phytochemical analyses of Moringa oleifera grown in Mexico. J Chem 2015:1–9

    Article  Google Scholar 

  34. Leone A, Fiorillo G, Criscuoli F, Ravasenghi S, Santagostini L, Fico G (2015) Nutritional characterization and phenolic profiling of Moringa oleifera leaves grown in Chad, Sahrawi Refugee Camps, and Haiti. Int J Mol Sci 16:18923–18937

    Article  CAS  Google Scholar 

  35. Gowrishankar R, Kumar M, Menon V, Divi S, Saravanan M, Magudapathy P, Panigrahi B, Nair K, Venkataramaniah K (2010) Trace element studies on Tinospora Cordifolia (Menispermaceae), Ocimum sanctum (Lamiaceae), Moringa oleifera (Moringaceae), and Phyllanthus niruri (Euphorbiaceae) Using PIXE. Biol Trace Elem Res 133:357–363

    Article  CAS  Google Scholar 

  36. Limmatvapirat C, Limmatvapirat S, Charoenteeraboon J, Phaechamud T (2015) Eleven heavy metals in Moringa Oleifera. Indian J Pharm Sci 77:485–490

    Article  CAS  Google Scholar 

  37. Melesse A, Steingass H, Boguhn J, Schollenberger M, Rodehutscord M (2012) Effects of elevation and sea-son on nutrient composition of leaves and green pods of Moringa stenopetala and Moringa oleifera. Agrofor Syst 86:505–518

    Article  Google Scholar 

  38. Kumssa D, Joy E, Young S, Odee D, Ander E, Broadley M (2017) Variation in the Mineral Element Concentration of Moringa oleifera Lam. and M. stenopetala Role in human nutrition. PLoS ONE 12:2–26

    Google Scholar 

  39. WHO (2005) Quality control methods for medicinal plant materials. World health organization, Geneva, Switzerland

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Correspondence to Molla Tefera.

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Adefa, T., Tefera, M. Heavy Metal Accumulation and Health Risk Assessment in Moringa Oleifera from Awi Zone, Ethiopia. Chemistry Africa 3, 1073–1079 (2020). https://doi.org/10.1007/s42250-020-00181-0

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