Skip to main content
SpringerLink
Log in

Extractions Without Organic Solvents: Advantages and Disadvantages

  • Case Report
  • Published:
Chemistry Africa Aims and scope Submit manuscript

Abstract

The process of extraction is well-known and widely used in numerous fields. Until recently, it has been performed in its basic level both in laboratory and industry. However, increased environmental concerns, development of environmental chemistry and wish to get safe products imposed new trends in extract production. The basic goals which have to be achieved are elimination of harmful solvents and increase of extraction yield. Different modern techniques can be used in order to accomplish these aims, but the special focus has been put on these one which rely on “green” solvents, such as subcritical water or supercritical carbon-dioxide. These techniques could be great alternative for the extraction of compounds of different polarity by setting operational parameters i.e. by varying solvent polarity. Obtained extracts do not contain residue of organic/toxic solvents and there is no need for their further purification. This makes such techniques economically acceptable from the industrial point of view. Yet, there is a question, which are the limitation of these techniques? Are they really so good? This review tends to show all advantages and disadvantages of novel extraction techniques and to give the comprehensive overview of all challenges in the process of developing of new environmentally-friendly techniques.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Log in via an institution

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Institutional subscriptions

Fig. 1
Fig. 2
Fig. 3

Similar content being viewed by others

References

  1. Mutalib LY (2015) Comparison between conventional and modern methods for extraction of Rosmarinus officinalis leaves. Zanco J Med Sci 19:1029–1034

    Article  Google Scholar 

  2. Chemat F, Huma Z, Kamran Khan M (2011) Applications of ultrasound in food technology: processing, preservation and extraction. Ultrason Sonochemistry 18:813–835

    Article  CAS  Google Scholar 

  3. Wang L, Weller CL (2006) Recent advances in extraction of nutraceuticals from plants. Trends Food Sci Technol 17:300–3012

    Article  CAS  Google Scholar 

  4. Buszewski B, Rafinska K, Cvetanović A, Walcyak J, Krakowska A, Rundicka J, Zeković Z (2019) Phytochemical analysis and biological activity of Lupinus luteus seeds extracts obtained by supercritical fluid extraction. Phytochem Lett 30:338–348

    Article  CAS  Google Scholar 

  5. Prakash B, Kujur A, Pratap Singh P, Kumar A, Yadav A (2017) Plants-derived bioactive compounds as functional food ingredients and food preservative. J Nutr Food Sci 2:1–7

    Google Scholar 

  6. Ribeiro A, Caleja C, Barros L, Santos-Buelga C, Barreiro MF, Ferreira IC (2016) Rosemary extracts in functional foods: extraction, chemical characterization and incorporation of free and microencapsulated forms in cottage cheese. Food Funct 18:2185–2196

    Article  CAS  Google Scholar 

  7. Cvjetko Bubalo M, Vidović S, Radojčić Redenković I, Jokić S (2018) New perspective in extraction of plant biologically active compounds by green solvents. Food Bioprod Process 109:52–73

    Article  CAS  Google Scholar 

  8. Švarc-Gajić J (2011) Samples and sample preparation in analytical chemistry. Nova-Publishers, New York

    Google Scholar 

  9. Nikolovski B (2009) Kinetics and modeling of extraction of oil from Junipers (Juniperus communis L.) and pumpkin seeds (Cucurbita pepo L.) by supercritical carbon-dioxide. Doctoral thesis, University of Novi Sad

  10. Cvetanović A, Švarc-Gajić J, Zeković Z, Jerković J, Zengin G, Gašić U, Tešić Ž, Mašković P, Soares C, Fatima Barroso M, Delerue-Matos C, Đurović S (2019) The influence of the extraction temperature on polyphenolic profiles and bioactivity of chamomile (Matricaria chamomilla L.) subcritical water extracts. Food Chem 271:328–337

    Article  CAS  PubMed  Google Scholar 

  11. Cvetanović A, Švarc-Gajić J, Gašić U, Tešić Ž, Zengin G, Zeković Z, Đurović S (2017) Isolation of apigenin from subcritical water extracts: optimization of the process. J Supercrit Fluids 120:32–42

    Article  CAS  Google Scholar 

  12. Yan Z, Luo X, Cong J, Zhang H, Ma H, Duan Y (2019) Subcritical water extraction, identification and antiproliferation ability on HepG2 of polyphenols from lotus seed epicarp. Ind Crops Prod 129:472–479

    Article  CAS  Google Scholar 

  13. Cvetanović A, Švarc-Gajić J, Zeković Z, Gašić U, Tešić Ž, Zengin G, Mašković P, Mahomoodally MF, Đurović S (2018) Subcritical water extraction as a cutting edge technology for the extraction of bioactive compounds from chamomile: influence of pressure on chemical composition and bioactivity of extracts. Food Chem 266:389–396

    Article  CAS  PubMed  Google Scholar 

  14. Cvetanović A, Švarc-Gajić J, Zeković Z, Mašković P, Đurović S, Zengin G, Delerue-Matos C, Lozano-Sánchez J, Jakšić A (2017) Chemical and biological insights on aronia stems extracts obtained by different extraction techniques: from wastes to functional products. J Supercrit Fluids 128:173–181

    Article  CAS  Google Scholar 

  15. Mašković P, Veličković V, Mitić M, Đurović S, Zeković Z, Radojković M, Cvetanović A, Švarc-Gajić J, Vujić J (2017) Summer savory extracts prepared by novel extraction methods resulted in enhanced biological activity. Ind Crops Prod 109:875–881

    Article  CAS  Google Scholar 

  16. Mašković P, Veličković V, Đurović S, Zeković Z, Radojković M, Cvetanović A, Švarc-Gajić J, Mitić M (2018) Biological activity and chemical profile of Lavatera thuringiaca L., extracts obtained by different extraction approaches. Phytomedicine 38:118–124

    Article  CAS  PubMed  Google Scholar 

  17. Cvetanović A, Švarc-Gajić J, Mašković P, Savić S, Lj Nikolić (2015) Antioxidant and biological activity of chamomile extracts obtained by different techniques: perspective of using superheated water for isolation of biologically active compounds. Ind Crops Prod 65:582–591

    Article  CAS  Google Scholar 

  18. Zeković Z, Cvetanović A, Švarc-Gajić J, Gorjanović S, Sužnjević D, Mašković P, Savić S, Radojković M, Đurović S (2017) Chemical and biological screening of stinging nettle leaves extracts obtained by modern extraction techniques. Ind Crops Prod 108:423–430

    Article  CAS  Google Scholar 

  19. Pavlic B, Vidovic S, Vladic J, Radosavljevic R, Zekovic Z (2015) Isolation of coriander (Coriandrum sativum L.) essential oil by green extractions versus traditional techniques. J Supercrit Fluids 99:23–28

    Article  CAS  Google Scholar 

Download references

Acknowledgements

The author would like to acknowledge the Serbian Ministry of Education, Science and Technological Development (Project no. TR31013) for the funding support of the research project.

Author information

Authors and Affiliations

  1. Department of Biotechnology and Pharmaceutical Engineering, Faculty of Technology, University of Novi Sad, Bulevar cara Lazara 1, Novi Sad, 21000, Serbia

    Aleksandra Cvetanović

Authors
  1. Aleksandra Cvetanović
    View author publications

    You can also search for this author in PubMed Google Scholar

Corresponding author

Correspondence to Aleksandra Cvetanović.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Cvetanović, A. Extractions Without Organic Solvents: Advantages and Disadvantages. Chemistry Africa 2, 343–349 (2019). https://doi.org/10.1007/s42250-019-00070-1

Download citation

  • Received:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s42250-019-00070-1

Keywords

Search

Navigation