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Non-contrast-enhanced MR angiography of the foot with flow spoiled-fresh blood imaging (FS-FBI): feasibility study and comparison of different scanning parameters

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Abstract

Objectives

To evaluate the feasibility of foot arteries using flow-spoiled-fresh blood imaging (FS-FBI) and to investigate how the FS-FBI scanning parameters affect the flow sensitivity and impact the depiction of pedal arteries.

Methods

The study included 46 young healthy volunteers examined by FS-FBI using 1.5T MRI scanner. Additional FS-FBI examination with different flip angles (FA) of the radiofrequency refocusing pulse and echo time (TE) was performed on 36 volunteers. Two radiologists separately analyzed and graded the venous contamination, image quality, displaying rate, signal-to-noise ratio (SNR), and contrast-to-noise ratio (CNR) values of foot arteries. Multi-sample Friedman test and paired two-sided Student’s t test were used for statistical analysis (P < 0.05).

Results

Average image quality and venous contamination score of all arteries was good. The demonstration rate of distal anterior and posterior tibial artery, and lateral plantar artery was 100%. Dorsalis pedis artery, first dorsal metatarsal artery, medial plantar artery, and plantar arch were demonstrated at a rate above 90%. The demonstration rate of medial tarsal artery was 73.9%, whereas arcuate artery was detected with a rate of only 5.4%. Significant differences in image quality, SNR, and CNR of distal arterial area were observed between different FA and TE.

Conclusion

Non-contrast-enhanced MR angiography of foot using FS-FBI enables clear separation of veins from arteries, and yields reliable depiction of the foot arterial tree in healthy volunteers. Distal arterial branches of foot can be better depicted by appropriate adjustment of the flow-sensitivity parameters.

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References

  1. Dong L, Li F, Jiang J, Zhang G. Techniques for covering soft tissue defects resulting from plantar ulcers in leprosy: part II. First toe web and dorsal foot flaps. Indian J Lepr. 1999;71(3):297–309.

    CAS  PubMed  Google Scholar 

  2. Martinez Villen G, Garcia Julve G. The arterial system of the first intermetatarsal space and its influence in toe-to-hand transfer: a report of 53 long-pedicle transfers. J Hand Surg. 2002;27(1):73–7.

    Article  CAS  Google Scholar 

  3. Pomposelli FB Jr, Marcaccio EJ, Gibbons GW, Campbell DR, Freeman DV, Burgess AM, et al. Dorsalis pedis arterial bypass: durable limb salvage for foot ischemia in patients with diabetes mellitus. J Vasc Surg. 1995;21(3):375–84.

    Article  PubMed  Google Scholar 

  4. Pomposelli FB, Kansal N, Hamdan AD, Belfield A, Sheahan M, Campbell DR, et al. A decade of experience with dorsalis pedis artery bypass: analysis of outcome in more than 1000 cases. J Vasc Surg. 2003;37(2):307–15.

    Article  PubMed  Google Scholar 

  5. Zhu J, Hu B. Sonography of the first dorsal metatarsal artery of the foot. J Clin Ultrasound. 2006;34(1):1–4.

    Article  PubMed  Google Scholar 

  6. Calvin AD, Misra S, Pflueger A. Contrast-induced acute kidney injury and diabetic nephropathy. Nat Rev Nephrol. 2010;6(11):679–88.

    Article  PubMed  PubMed Central  Google Scholar 

  7. Sadowski EA, Bennett LK, Chan MR, Wentland AL, Garrett AL, Garrett RW, et al. Nephrogenic systemic fibrosis: risk factors and incidence estimation. Radiology. 2007;243(1):148–57.

    Article  PubMed  Google Scholar 

  8. Shellock FG, Spinazzi A. MRI safety update 2008: part 1, MRI contrast agents and nephrogenic systemic fibrosis. Am J Roentgenol. 2008;191(4):1129–39.

    Article  Google Scholar 

  9. Miyazaki M, Takai H, Sugiura S, Wada H, Kuwahara R, Urata J. Peripheral MR angiography: separation of arteries from veins with flow-spoiled gradient pulses in electrocardiography-triggered three-dimensional half-Fourier fast spin-echo imaging. Radiology. 2003;227(3):890–6.

    Article  PubMed  Google Scholar 

  10. Nakamura K, Miyazaki M, Kuroki K, Yamamoto A, Hiramine A, Admiraal-Behloul F. Noncontrast-enhanced peripheral MRA: technical optimization of flow-spoiled fresh blood imaging for screening peripheral arterial diseases. Magn Reson Med. 2011;65(2):595–602.

    Article  PubMed  Google Scholar 

  11. Hahn WY, Hecht EM, Friedman B, Babb JS, Jacobowitz GR, Lee VS. Distal lower extremity imaging: prospective comparison of 2-dimensional time of flight, 3-dimensional time-resolved contrast-enhanced magnetic resonance angiography, and 3-dimensional bolus chase contrast-enhanced magnetic resonance angiography. J Comput Assist Tomogr. 2007;31(1):29–36.

    Article  PubMed  Google Scholar 

  12. Kaufman JA, McCarter D, Geller SC, Waltman AC. Two-dimensional time-of-flight MR angiography of the lower extremities: artifacts and pitfalls. Am J Roentgenol. 1998;171(1):129–35.

    Article  CAS  Google Scholar 

  13. Edelman RR, Sheehan JJ, Dunkle E, Schindler N, Carr J, Koktzoglou I. Quiescent-interval single-shot unenhanced magnetic resonance angiography of peripheral vascular disease: technical considerations and clinical feasibility. Magn Reson Med. 2010;63(4):951–8.

    Article  PubMed  PubMed Central  Google Scholar 

  14. Storey P, Atanasova IP, Lim RP, Xu J, Kim D, Chen Q, et al. Tailoring the flow sensitivity of fast spin-echo sequences for noncontrast peripheral MR angiography. Magn Reson Med. 2010;64(4):1098–108.

    Article  PubMed  PubMed Central  Google Scholar 

  15. Fan Z, Sheehan J, Bi X, Liu X, Carr J, Li D. 3D noncontrast MR angiography of the distal lower extremities using flow-sensitive dephasing (FSD)-prepared balanced SSFP. Magn Reson Med. 2009;62(6):1523–32.

    Article  PubMed  PubMed Central  Google Scholar 

  16. Schubert T, Takes M, Aschwanden M, Klarhoefer M, Haas T, Jacob AL, et al. Non-enhanced, ECG-gated MR angiography of the pedal vasculature: comparison with contrast-enhanced MR angiography and digital subtraction angiography in peripheral arterial occlusive disease. Eur Radiol. 2016;26(8):2705–13.

    Article  PubMed  Google Scholar 

  17. Fan Z, Zhou X, Bi X, Dharmakumar R, Carr JC, Li D. Determination of the optimal first-order gradient moment for flow-sensitive dephasing magnetization-prepared 3D noncontrast MR angiography. Magn Reson Med. 2011;65(4):964–72.

    Article  PubMed  PubMed Central  Google Scholar 

  18. Ruhl KM, Katoh M, Langer S, Mommertz G, Guenther RW, Niendorf T, et al. Time-resolved 3D MR angiography of the foot at 3 T in patients with peripheral arterial disease. Am J Roentgenol. 2008;190(6):W360–4.

    Article  Google Scholar 

  19. Kim JW, Choi YJ, Lee HJ, Yi KH, Kim HJ, Hu KS. Anatomic study of the dorsalis pedis artery, first metatarsal artery, and second metatarsal bone for mandibular reconstruction. J Oral Maxillofac Surg. 2015;73(8):1627–36.

    Article  PubMed  Google Scholar 

  20. DiLandro AC, Lilja EC, Lepore FL, Viscovich JB, Campion N, Datta UK, et al. The prevalence of the arcuate artery: a cadaveric study of 72 feet. J Am Podiatr Med Assoc. 2001;91(6):300–5.

    Article  CAS  PubMed  Google Scholar 

  21. Hamada N, Ikuta Y, Ikeda A. Arteriographic study of the arterial supply of the foot in one hundred cadaver feet. Acta Anat. 1994;151(3):198–206.

    Article  CAS  PubMed  Google Scholar 

  22. Miyazaki M, Sugiura S, Tateishi F, Wada H, Kassai Y, Abe H. Non-contrast-enhanced MR angiography using 3D ECG-synchronized half-Fourier fast spin echo. J Magn Reson Imaging. 2000;12(5):776–83.

    Article  CAS  PubMed  Google Scholar 

  23. Busse RF, Brau AC, Vu A, Michelich CR, Bayram E, Kijowski R, et al. Effects of refocusing flip angle modulation and view ordering in 3D fast spin echo. Magn Reson Med. 2008;60(3):640–9.

    Article  PubMed  PubMed Central  Google Scholar 

  24. Alsop DC. The sensitivity of low flip angle RARE imaging. Magn Reson Med. 1997;37(2):176–84.

    Article  CAS  PubMed  Google Scholar 

  25. Hinks RS, Constable RT. Gradient moment nulling in fast spin echo. Magn Reson Med. 1994;32(6):698–706.

    Article  CAS  PubMed  Google Scholar 

Download references

Acknowledgements

This project supported by the Foundation for Young Scholars of Fujian Provincial Health Commission, China (Grant No. 2017-1-49).

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Authors and Affiliations

  1. Department of Radiology, First Affiliated Hospital of Fujian Medical University, 20 Cha-Zhong Road, Fuzhou, 350005, Fujian, People’s Republic of China

    Yuyang Zhang, Shuai Yu, Dejun She, Dehua Chen & Dairong Cao

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  1. Yuyang Zhang
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  2. Shuai Yu
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  3. Dejun She
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  5. Dairong Cao
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Correspondence to Dairong Cao.

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Zhang, Y., Yu, S., She, D. et al. Non-contrast-enhanced MR angiography of the foot with flow spoiled-fresh blood imaging (FS-FBI): feasibility study and comparison of different scanning parameters. Chin J Acad Radiol 1, 85–93 (2019). https://doi.org/10.1007/s42058-019-00014-1

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  • DOI: https://doi.org/10.1007/s42058-019-00014-1

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