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Evaluation of the feasibility and preference of Nox-A1 type 2 ambulatory device for unattended home sleep test: a randomized crossover study

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Abstract

There is an increasing need for portable sleep monitoring in clinical practice, but there is no comparative study that used the same device for home and in-laboratory sleep monitoring and device close to full polysomnography (PSG) to evaluate the feasibility and preference of home unattended sleep monitoring. Twenty male participants with high risk for moderate to severe OSA based on the STOP-BANG questionnaire were included. The participants were randomly assigned to group A (home unattended monitoring after in-laboratory monitoring) or group B (in-laboratory monitoring after home unattended monitoring). A 2-week washout period was implemented between the sleep tests. All hook-up procedures were performed in laboratory. Participants were asked to complete a questionnaire after finishing each sleep test. There was no difference in sleep efficiency, arousal index, or time spent in each sleep stage between the two monitoring modes using Nox-A1. Additionally, other respiratory parameters such as apnea–hypopnea index (AHI), supine AHI, and snoring time did not differ. A high and similar sensor quality for airflow, oxygen, and respiratory effort was observed in both monitoring groups. Patient’s feelings and satisfaction with the test were similar between in-laboratory and home monitoring, but preference rate for the in-laboratory test was higher than that for home monitoring (70% vs. 30%, respectively). These data suggest that home unattended monitoring with Nox-A1 type 2 ambulatory device is a feasible alternative diagnostic mode for high risk of moderate to severe OSA, yielding reliable quality recordings and high patient satisfaction.

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Acknowledgements

We thank Kwangwoo MeDix, Inc. for supplying the Nox-A1 portable devices, Cho-Hee Hong for conducting sleep analysis, and Min-Joo Jeon for performing all hook-up procedures for the in-laboratory and home sleep test. This randomized crossover trial was registered at Clinical Research Information Service (KCT0002914).

Funding

This work was supported by Grant no. 06-2017-2300 from the SNUH Research Fund and Kwangwoo Medix, Inc. D.W.Y received a scholarship from the BK21-plus education program provided by the National Research Foundation of Korea.

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Author notes

  1. Dae Wui Yoon, Il-Hee Hong and Inkyung Baik contributed equally to this work.

Authors and Affiliations

  1. Obstructive Upper airway Research (OUaR) Laboratory, Department of Pharmacology, Seoul National University College of Medicine, Seoul, South Korea

    Dae Wui Yoon & Hyun-Woo Shin

  2. Seoul Sleep Clinic, Seoul, South Korea

    Il-Hee Hong

  3. Department of Foods and Nutrition, College of Science and Technology, Kookmin University, Seoul, South Korea

    Inkyung Baik

  4. Department of Otorhinolaryngology-Head and Neck Surgery, Seoul National University Hospital, 103 Daehak-ro, Jongno-gu, Seoul, 110-799, South Korea

    Hyun-Woo Shin

  5. Ischemic/Hypoxic Disease Institute, Seoul National University College of Medicine, Seoul, South Korea

    Hyun-Woo Shin

  6. Cancer Research Institute, Seoul National University College of Medicine, Seoul, South Korea

    Hyun-Woo Shin

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  1. Dae Wui Yoon
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  2. Il-Hee Hong
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Contributions

Conception and design: DW and HW; data collection: DW and IH; analysis and interpretation of data: DW, IH, IK, and HW; drafting the manuscript: DW and IH; revision for important intellectual content: DW, IH, IK, and HW.

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Correspondence to Hyun-Woo Shin.

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The authors declare that they have no conflict of interest with the contents of this article.

Ethical approval

All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki Declaration. The Institutional Review Board at Seoul National University Hospital reviewed and approved the study protocol. The protocol was approved by the Institutional Review Board at the Seoul National University Hospital (No. 1706-041-858).

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Written informed consent was obtained from all individual participants included in the study.

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Yoon, D.W., Hong, IH., Baik, I. et al. Evaluation of the feasibility and preference of Nox-A1 type 2 ambulatory device for unattended home sleep test: a randomized crossover study. Sleep Biol. Rhythms 17, 297–304 (2019). https://doi.org/10.1007/s41105-019-00213-4

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  • DOI: https://doi.org/10.1007/s41105-019-00213-4

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