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Screening of In Vitro Antibacterial Property of Hematite (α-Fe2O3) Nanoparticles: A Green Approach

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Abstract

This study explores the fabrication of hematite (α-Fe2O3) nanoparticles utilizing aqueous extracts of Plectranthus amboinicus, which act as reducing and stabilizing agents. The prepared hematite (α-Fe2O3) nanoparticles have been characterized by TGA, PXRD, FT-IR, Raman, DRS UV–visible, Photoluminescence, SEM, Particle size distribution, and zeta potential measurements (DLS), respectively. According to the XRD reports, hematite (α-Fe2O3) nanoparticles are rhombohedral with a crystallite size of 7.0 nm. As of the FT-IR spectrum, the peaks attained at 544 and 447 cm−1 are attributes of Fe–O stretching in α-Fe2O3. As a result of Raman analysis, the existence of vibration modes of hematite (α-Fe2O3) nanoparticles was confirmed. Through the DRS UV–visible reflectance, the bandgap energy of hematite (α-Fe2O3) nanoparticles was detected to be 2.0 eV. The photoluminescence spectrum shows band edge emission at 552 nm. The morphology of hematite (α-Fe2O3) nanoparticles was aggregated with dense irregular shape and highly porous. Particle size distribution and zeta potential value of hematite (α-Fe2O3) nanoparticles were reported at 40 nm and − 35 mV, respectively. These nanoparticles exhibit strong antibacterial activity at a concentration of 30 μg/mL and also exhibit substantial minimum inhibition concentration value for gram-positive and gram-negative bacteria. The proposed strategy is therefore rapid, simple, cost-effective, and environmentally friendly which can be employed for the fabrication of hematite (α-Fe2O3) nanoparticles and can be used as a potent antibacterial agent.

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Funding

The author, Dr. K. Venkatachalam gratefully acknowledges the financial assistance from the Department of Science and Technology, India for the DST-SERB Project (Ref. No. EEQ/2016/000559, date.: 06.02.2017).

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Correspondence to Venkatachalam Kandan.

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Prashanna Suvaitha Sundara Selvam – Conceptualization; Methodology; Formal analysis; Investigation; Resources; Data Curation; Writing original draft preparation; Writing-review and editing. Sangeetha Govindan – Methodology. Bhavani Perumal – Visualization. Venkatachalam Kandan – Writing-review, Funding acquisition; Visualization; Supervision; Project administration.

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Sundara Selvam, P.S., Govindan, S., Perumal, B. et al. Screening of In Vitro Antibacterial Property of Hematite (α-Fe2O3) Nanoparticles: A Green Approach. Iran J Sci Technol Trans Sci 45, 177–187 (2021). https://doi.org/10.1007/s40995-020-00995-0

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  • DOI: https://doi.org/10.1007/s40995-020-00995-0

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