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Synthesis, Magneto-structural Properties and Colloidal Stability Studies of Ni0.3Zn0.7Fe2O4 Nanoparticles Coated with Pluronic P123 Block Copolymer for Potential Biomedical Applications

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Abstract

Spinel Ni0.3Zn0.7Fe2O4 (NZFO) magnetic nanoparticles was prepared by the low temperature auto-combustion method using a glycine fuel-rich composition without any further heat treatment at high temperature. Subsequently, the synthesized MNPs were coated with Pluronic P123 (PP123) after its surface was functionalized with oleic acid (OA). The effect of the coatings on the morphology, structural and magnetic properties of NZFO nanoparticles was studied using powder X-ray diffraction (XRD), Fourier transform infrared, thermogravimetric analysis, field emission scanning electron microscopy (FE-SEM) and vibrating sample magnetometer (VSM). The colloidal behaviour of coated MNPs in physiological saline medium like water or phosphate buffer saline (PBS) was also studied by zeta potential measurements. XRD results showed the formation of cubic spinel crystalline phase with and without OA–PP123 coatings. Also, after OA–PP123 coating, the crystallite size (from Scherrer formula) decreases from 55 to 53 nm. However, an enlargement in the particle size and a reduction in agglomeration were observed from FE-SEM results when the nanoparticles were coated with OA–PP123. VSM measurements showed ferromagnetic behaviour at room temperature before and after coating. The colloidal stability study of the coated sample revealed a considerable high zeta potential value at physiological pH (7.4) highlighting its potential biomedical applications.

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Acknowledgements

This work would not have been possible without the visiting research grant given to Dr. Ehi-Eromosele C.O. by the International Centre for Materials Science, Jawaharlal Nehru Centre for Advanced Scientific Research, Bangalore, India.

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Authors and Affiliations

  1. Department of Chemistry, Covenant University, PMB 1023, Ota, Nigeria

    Cyril O. Ehi-Eromosele & Benedict I. Ita

  2. Department of Pure and Applied Chemistry, University of Calabar, Calabar, Nigeria

    Benedict I. Ita

  3. Department of Biological Sciences, Covenant University, PMB 1023, Ota, Nigeria

    Emeka E. J. Iweala

Authors
  1. Cyril O. Ehi-Eromosele
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  2. Benedict I. Ita
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  3. Emeka E. J. Iweala
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Correspondence to Cyril O. Ehi-Eromosele.

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Ehi-Eromosele, C.O., Ita, B.I. & Iweala, E.E.J. Synthesis, Magneto-structural Properties and Colloidal Stability Studies of Ni0.3Zn0.7Fe2O4 Nanoparticles Coated with Pluronic P123 Block Copolymer for Potential Biomedical Applications. Iran J Sci Technol Trans Sci 42, 209–217 (2018). https://doi.org/10.1007/s40995-018-0486-z

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  • DOI: https://doi.org/10.1007/s40995-018-0486-z

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