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From Surprise to Suspicion: Ovarian Metastases

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Abstract

Purpose

From all ovarian tumors, the metastases to ovaries comprise just 3–10 %. However, rarely surgeons may suspect preoperatively the diagnosis. Thus, the surgeon’s point of view about three cases of this challenging entity is presented.

Cases

The first was a finding by our pathologist in a case with an apparently carcinoma of the ovary; it was a cervical carcinoma with metastasis to ovaries. The second case was another seemingly primary ovarian carcinoma. During her surgery, a synchronous sigmoidal mass and an ovarian tumor were detected, so the notion of a probable colorectal cancer with metastases to the ovary was done, and both lesions were extirpated; the suspicion was proved. In the third case, there were a synchronic breast cancer and an ovarian tumor, so a preoperative suspicion of a metastatic breast carcinoma to the ovary was done. A modified radical mastectomy and a cytoreductive ovarian cancer surgery were performed; the suspicion was verified.

Conclusion

Nowadays, a definitive preoperative diagnosis of the metastasis to ovaries is impossible. Only in a rare clinical scenario, this option could be suspected by surgeons.

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References

  1. Terzic M, Dotlic J, Brndusic N, Arsenovic N, Likic I, Ladjevic N, et al. Histopathological diagnoses of adnexal masses: which parameters are relevant in preoperative assessment? Ginekol Pol. 2013;84(8):700–8.

    Article  PubMed  Google Scholar 

  2. Young RH. From Krukenberg to today: the ever present problems posed by metastatic tumors in the ovary: Part I. Historical perspective, general principles, mucinous tumors including the Krukenberg tumor. Adv Anat Pathol. 2006;13(5):205–27.

    Article  PubMed  Google Scholar 

  3. Weiqi L, Lei Y, Xishi L, Sun-Wei G. Identification of prognostic factors for Krukenberg tumor. Gynecol Minim Invasive Ther. 2013;2(2):52–6.

    Article  Google Scholar 

  4. Guzel AB, Gulec UK, Paydas S, Khatib G, Gumurdulu D, Vardar MA, et al. Preoperative evaluation, clinical characteristics, and prognostic factors of nongenital metastatic ovarian tumors: review of 48 patients. Eur J Gynaecol Oncol. 2012;33(5):493–7.

    CAS  PubMed  Google Scholar 

  5. Mateş IN, Iosif C, Bănceanu G, Ionescu M, Peltecu G, Dinu D, et al. Features of Krukenberg-type tumors–clinical study and review. Chirurgia (Bucur). 2008;103(1):23–38.

    Google Scholar 

  6. Turan T, Aykan B, Koc S, Boran N, Tulunay G, Karacay O, et al. Analysis of metastatic ovarian tumors from extragenital primary sites. Tumori. 2006;92(6):491–5.

    PubMed  Google Scholar 

  7. Alvarado-Cabrero I, Rodríguez-Gómez A, Castelan-Pedraza J, Valencia-Cedillo R. Metastatic ovarian tumors: a clinicopathologic study of 150 cases. Anal Quant Cytopathol Histpathol. 2013;35(5):241–8.

    PubMed  Google Scholar 

  8. Yada-Hashimoto N, Yamamoto T, Kamiura S, Seino H, Ohira H, Sawai K, et al. Metastatic ovarian tumors: a review of 64 cases. Gynecol Oncol. 2003;89(2):314–7.

    Article  PubMed  Google Scholar 

  9. Jiang R, Tang J, Cheng X, Zang RY. Surgical treatment for patients with different origins of Krukenberg tumors: outcomes and prognostic factors. Eur J Surg Oncol. 2009;35(1):92–7.

    Article  CAS  PubMed  Google Scholar 

  10. Moore RG, Chung M, Granai CO, Gajewski W, Steinhoff MM. Incidence of metastasis to the ovaries from nongenital tract primary tumors. Gynecol Oncol. 2004;93(1):87–91.

    Article  PubMed  Google Scholar 

  11. Cho KC, Gold BM. Computed tomography of Krukenberg tumors. AJR. 1985;145(2):285–8.

    Article  CAS  PubMed  Google Scholar 

  12. Lewis MR, Euscher ED, Deavers MT, Silva EG, Malpica A. Metastatic colorectal adenocarcinoma involving the ovary with elevated serum CA125: a potential diagnostic pitfall. Gynecol Oncol. 2007;105(2):395–8.

    Article  CAS  PubMed  Google Scholar 

  13. Sakakura C, Hagiwara A, Yamazaki J, Takagi T, Hosokawa K, Shimomura K, et al. Management of postoperative follow-up and surgical treatment for Krukenberg tumor from colorectal cancers. Hepatogastroenterology. 2004;51(59):1350–3.

    PubMed  Google Scholar 

  14. Garrett CR, George B, Viswanathan C, Bhadkamkar NA, Wen S, Baladandayuthapani V, et al. Survival benefit associated with surgical oophorectomy in patients with colorectal cancer metastatic to the ovary. Clin Colorectal Cancer. 2012;11(3):191–4.

    Article  PubMed  Google Scholar 

  15. Ortiz-Mendoza CM, Catarino DA. A rare tumor resembling ovarian cysts: mucocele of the appendix. Int J Gynecol Obstet Res. 2013;1(1):1–3. doi:10.14205/2309-4400.2013.01.01.1.

    Google Scholar 

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Correspondence to Carlos Manuel Ortiz-Mendoza.

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Research Involving Human Participants and/or Animals

This article does not contain any experimental studies with human participants performed by any of the authors.

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Ortiz-Mendoza, C.M., Catarino-Dircio, A. From Surprise to Suspicion: Ovarian Metastases. Indian J Gynecol Oncolog 14, 42 (2016). https://doi.org/10.1007/s40944-016-0071-3

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  • DOI: https://doi.org/10.1007/s40944-016-0071-3

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