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Biosensing Technologies for Medical Applications, Manufacturing, and Regenerative Medicine

  • Artificial Tissues (A Atala and JG Hunsberger, Section Editors)
  • Published:
Current Stem Cell Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

The review covers biosensing technologies, their impact on healthcare, and future applications.

Recent Findings

Advancements in biosensing technologies that can detect a wide range of bioanalytes at reduced costs are described.

Summary

Biosensing technologies are becoming essential for advancing human healthcare. A biosensor detects a specific biological analyte and monitors its function within a biological milieu; this technology has gained the attention of many researchers worldwide owing to its importance in medical applications. Noninvasive, cost-effective, high-resolution, and portable biosensors can be extensively utilized; however, there remain numerous challenges to overcome, including real-time, in vivo monitoring of organ functionality in high-risk patients. Herein, we review biosensors, their fabrication, and their various uses. Additionally, we provide an overview of their role in medical applications such as cardiovascular disease, diabetes, wound healing, cancer diagnosis, and prosthesis fabrication. Furthermore, the applications of biosensing technologies in regenerative medicine such as biomanufacturing procedures, organ-on-a-chip technologies, and indicators of therapeutic efficacy are discussed. Finally, an overall perspective of the field and its potential future directions are considered.

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Author notes

  1. Elham Ghadiri and Jareer Kassis contributed equally to this work.

Authors and Affiliations

  1. Wake Forest Institute for Regenerative Medicine, Wake Forest School of Medicine, Winston-Salem, NC, USA

    Ashkan Shafiee, Jareer Kassis, Nima Pourhabibi Zarandi & Anthony Atala

  2. Department of Chemistry, Duke University, Durham, NC, USA

    Elham Ghadiri

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  1. Ashkan Shafiee
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  2. Elham Ghadiri
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Correspondence to Ashkan Shafiee.

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Ashkan Shafiee, Elham Ghadiri, Jareer Kassis, Nima Pourhabibi Zarandi, and Anthony Atala declare that they have no conflict of interest.

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Shafiee, A., Ghadiri, E., Kassis, J. et al. Biosensing Technologies for Medical Applications, Manufacturing, and Regenerative Medicine. Curr Stem Cell Rep 4, 105–115 (2018). https://doi.org/10.1007/s40778-018-0123-y

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