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Insights since FDA Approval of Hypoglossal Nerve Stimulation for the Treatment of Obstructive Sleep Apnea

  • Sleep and Otolaryngology (H Gouveris, Section Editor)
  • Published:
Current Sleep Medicine Reports Aims and scope Submit manuscript

An Erratum to this article was published on 31 August 2017

This article has been updated

Abstract

Purpose of Review

The literature on hypoglossal nerve stimulation (HNS) for the treatment of moderate-to-severe obstructive sleep apnea (OSA) was reviewed from 2014, the time of FDA approval for the Inspire Systems device, to 2017 for themes that might be useful conceptually and practically in the consideration of this new non-anatomic surgical therapy.

Recent Findings

There are now further follow-up articles since the 12-month results for apnea reduction (Stimulation Therapy for Apnea Reduction (STAR)) trial of the Inspire device and post-approval publications which report similar and/or improved apnea-hypopnea index outcomes. Other emerging themes include drug-induced sedation endoscopy (DISE) as a tool in assessment of eligibility and a more detailed understanding of mechanisms for an HNS effects.

Summary

The post-STAR literature provides guidelines for an integrated coordination of medicine and surgery to appropriately screen and manage patients.

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Change history

  • 31 August 2017

    An erratum to this article has been published.

References

Papers of particular interest, published recently, have been highlighted as: •Of importance ••Of major importance

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Author information

Authors and Affiliations

  1. Department of Otolaryngology, University of California, 2233 Post Street, San Francisco, CA, 94115, USA

    Madeleine P. Strohl

  2. Second Department of Internal Medicine (Department of Respiratory Medicine), Nara Medical University, 840 Shijo-cho, Kashihara, Nara, 634-8522, Japan

    Motoo Yamauchi

  3. Department of Surgery, Peking University People’s Hospital, 11 Xizhimennan Street, Xicheng District, Beijing, 100044, China

    Zhe Peng

  4. Department of Medicine, Division of Pulmonary, Critical Care and Sleep Medicine, Case School of Medicine, Cleveland, OH, USA

    Kingman P. Strohl

  5. Veterans Affairs Cleveland DVA Medical Center, 111j(w), 10701 East Blvd, Cleveland, OH, 44106, USA

    Kingman P. Strohl

Authors
  1. Madeleine P. Strohl
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  2. Motoo Yamauchi
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  3. Zhe Peng
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  4. Kingman P. Strohl
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Corresponding author

Correspondence to Kingman P. Strohl.

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Conflict of Interest

Madeleine M. Strohl, Motoo Yamauchi, and Zhe Peng declare no conflicts of interest. Kingman P. Strohl reports a grant from Inspire Medical Systems for STAR trial site PI and post-approval study PI.

Human and Animal Rights and Informed Consent

This article does not contain any studies with human or animal subjects performed by any of the authors.

Additional information

The original version of this article was revised: The middle initial of the first author listed in the title was incorrect, and the correct name is Madeleine P. Strohl, as noted in the addresses. Her name is now corrected in the author group of this article.

This article is part of the Topical Collection on Sleep and Otolaryngology

An erratum to this article is available at https://doi.org/10.1007/s40675-017-0089-9.

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Strohl, M.P., Yamauchi, M., Peng, Z. et al. Insights since FDA Approval of Hypoglossal Nerve Stimulation for the Treatment of Obstructive Sleep Apnea. Curr Sleep Medicine Rep 3, 133–141 (2017). https://doi.org/10.1007/s40675-017-0088-x

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