Abstract
Purpose of review
The objective of the present review is to give an update on newly available literature concerning positional therapy as a treatment in positional dependent OSA patients.
Methods
A systematic review
Recent Findings
Five prospective cohort studies, six randomized controlled trials and one retrospective study were included in this review. All studies published on new-generation devices for positional therapy (PT) have shown a significant reduction in the AHI and percentage of supine sleeping time in patients with obstructive sleep apnea (OSA). The effectiveness of sleep position trainer (SPT) compared to OAT was similar and the results of additional treatment with PT in patients with residual positional obstructive sleep apnea (POSA) after upper airway surgery seemed to be effective. No evidence was found that confirms a behavioural or training effect of PT. Overall, the effectiveness and compliance are high during short-time follow-up as well as in long-term studies.
Summary
PT with new-generation devices have shown to be effective in reducing total percentage of supine sleep time and total AHI. Additional treatment with PT in patients with residual POSA after upper airway surgery shows promising results and also combination therapy of SPT + MAD leads to a higher therapeutic efficacy when compared to one of the treatment modalities alone. Short-term and long-term compliance in SPT users is high, but due to high drop out during long-term follow-up, proper selection of PP to identify predictors of non-responders is important.
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References
Papers of particular interest, published recently, have been highlighted as: •Of importance •• Of major mportance
Heinzer R, Marti-Soler H, Haba-Rubio J. Prevalence of sleep apnoea syndrome in the middle to old age general population. Lancet Respir Med. 2016;4(2):e5–6. doi:10.1016/S2213-2600(16)00006-0.
Richard W, Kox D, den Herder C, Laman M, van Tinteren H, de Vries N. The role of sleep position in obstructive sleep apnea syndrome. Eur Arch Otorhinolaryngol. 2006;263(10):946–50. doi:10.1007/s00405-006-0090-2.
• van Maanen JP, Richard W, Van Kesteren ER, Ravesloot MJ, Laman DM, Hilgevoord AA, et al. Evaluation of a new simple treatment for positional sleep apnoea patients. J Sleep Res. 2012;21(3):322–9. doi:10.1111/j.1365-2869.2011.00974.x. The short-term follow-up study by van Maanen et al. was the basis for the long-term follow-up study on position therapy with the Sleep Position Trainer, a new-generation device which is currently used in POSA patients.
George CF, Smiley A. Sleep apnea & automobile crashes. Sleep. 1999;22(6):790–5.
Ravesloot MJ, de Vries N. One hundred consecutive patients undergoing drug-induced sleep endoscopy: results and evaluation. Laryngoscope. 2011;121(12):2710–6. doi:10.1002/lary.22369.
Oksenberg A, Khamaysi I, Silverberg DS, Tarasiuk A. Association of body position with severity of apneic events in patients with severe nonpositional obstructive sleep apnea. Chest. 2000;118(4):1018–24.
Saigusa H, Suzuki M, Higurashi N, Kodera K. Three-dimensional morphological analyses of positional dependence in patients with obstructive sleep apnea syndrome. Anesthesiology. 2009;110(4):885–90. doi:10.1097/ALN.0b013e31819b5d57.
Walsh JH, Leigh MS, Paduch A, Maddison KJ, Armstrong JJ, Sampson DD, et al. Effect of body posture on pharyngeal shape and size in adults with and without obstructive sleep apnea. Sleep. 2008;31(11):1543–9.
Cartwright RD. Effect of sleep position on sleep apnea severity. Sleep. 1984;7(2):110–4.
Marklund M, Persson M, Franklin KA. Treatment success with a mandibular advancement device is related to supine-dependent sleep apnea. Chest. 1998;114(6):1630–5.
Permut I, Diaz-Abad M, Chatila W, Crocetti J, Gaughan JP, D'Alonzo GE, et al. Comparison of positional therapy to CPAP in patients with positional obstructive sleep apnea. J Clin Sleep Med. 2010;6(3):238–43.
Mador MJ, Kufel TJ, Magalang UJ, Rajesh SK, Watwe V, Grant BJ. Prevalence of positional sleep apnea in patients undergoing polysomnography. Chest. 2005;128(4):2130–7. doi:10.1378/chest.128.4.2130.
Bignold JJ, Mercer JD, Antic NA, McEvoy RD, Catcheside PG. Accurate position monitoring and improved supine-dependent obstructive sleep apnea with a new position recording and supine avoidance device. J Clin Sleep Med. 2011;7(4):376–83. doi:10.5664/JCSM.1194.
Oksenberg A, Silverberg DS, Arons E, Radwan H. Positional vs nonpositional obstructive sleep apnea patients: anthropomorphic, nocturnal polysomnographic, and multiple sleep latency test data. Chest. 1997;112(3):629–39.
Ravesloot MJ, Frank MH, van Maanen JP, Verhagen EA, de Lange J, de Vries N. Positional OSA part 2: retrospective cohort analysis with a new classification system (APOC). Sleep Breath. 2016;20(2):881–8. doi:10.1007/s11325-015-1206-y.
Wenzel S, Smith E, Leiacker R, Fischer Y. Efficacy and longterm compliance of the vest preventing the supine position in patients with obstructive sleep apnea. Laryngorhinootologie. 2007;86(8):579–83. doi:10.1055/s-2007-966179.
Bignold JJ, Deans-Costi G, Goldsworthy MR, Robertson CA, McEvoy D, Catcheside PG, et al. Poor long-term patient compliance with the tennis ball technique for treating positional obstructive sleep apnea. J Clin Sleep Med. 2009;5(5):428–30.
Eijsvogel MM, Ubbink R, Dekker J, Oppersma E, de Jongh FH, van der Palen J, et al. Sleep position trainer versus tennis ball technique in positional obstructive sleep apnea syndrome. J Clin Sleep Med. 2015;11(2):139–47. doi:10.5664/jcsm.4460.
Vanderveken OM, Dieltjens M, Wouters K, De Backer WA, Van de Heyning PH, Braem MJ. Objective measurement of compliance during oral appliance therapy for sleep-disordered breathing. Thorax. 2013;68(1):91–6. doi:10.1136/thoraxjnl-2012-201900.
Ravesloot MJ, de Vries N, Stuck BA. Treatment adherence should be taken into account when reporting treatment outcomes in obstructive sleep apnea. Laryngoscope. 2014;124(1):344–5. doi:10.1002/lary.24302.
• van Maanen JP, de Vries N. Long-term effectiveness and compliance of positional therapy with the sleep position trainer in the treatment of positional obstructive sleep apnea syndrome. Sleep. 2014;37(7):1209–15. doi:10.5665/sleep.3840. The study by van Maanen et al. is the first study which evaluated the long-term effectiveness and compliance of positional therapy with the sleep position trainer and therefore fundamental for treatment with position therapy in POSA patients.
•• Ravesloot MJ, White D, Heinzer R, Oksenberg A, Pepin JL. Efficacy of the new generation of devices for positional therapy for patients with positional obstructive sleep apnea: a systematic review of the literature and meta-analysis. J Clin Sleep Med. 2017;13(6):813–24. The study by Ravesloot et al. is the most recent systematic review and meta-analysis on new-generation devices.
Benoist LB, Verhagen M, Torensma B, van Maanen JP, de Vries N. Positional therapy in patients with residual positional obstructive sleep apnea after upper airway surgery. Sleep Breath. 2016; doi:10.1007/s11325-016-1397-x.
Scarlata S, Rossi Bartoli I, Santangelo S, Giannunzio G, Pedone C, Antonelli IR. Short-term effects of a vibrotactile neck-based treatment device for positional obstructive sleep apnea: preliminary data on tolerability and efficacy. J Thorac Dis. 2016;8(7):1820–4. doi:10.21037/jtd.2016.04.69.
Laub RR, Tonnesen P, Jennum PJ. A sleep position trainer for positional sleep apnea: a randomized, controlled trial. J Sleep Res. 2017; doi:10.1111/jsr.12530.
Benoist L, de Ruiter M, de Lange J, de Vries N. A randomized, controlled trial of positional therapy versus oral appliance therapy for position-dependent sleep apnea. Sleep Med. 2017;34:109–17.
Levendowski D, Cunnington D, Swieca J, Westbrook P. User compliance and behavioral adaptation associated with supine avoidance therapy. Behav Sleep Med. 2016:1–11. doi:10.1080/15402002.2016.1163704.
Dieltjens M, Braem MJ, Van de Heyning PH, Wouters K, Vanderveken OM. Prevalence and clinical significance of supine-dependent obstructive sleep apnea in patients using oral appliance therapy. J Clin Sleep Med. 2014;10(9):959–64. doi:10.5664/jcsm.4024.
van Maanen JP, Ravesloot MJ, Witte BI, Grijseels M, de Vries N. Exploration of the relationship between sleep position and isolated tongue base or multilevel surgery in obstructive sleep apnea. Eur Arch Otorhinolaryngol. 2012;269(9):2129–36. doi:10.1007/s00405-012-1995-6.
van Maanen JP, Witte BI, de Vries N. Theoretical approach towards increasing effectiveness of palatal surgery in obstructive sleep apnea: role for concomitant positional therapy? Sleep Breath. 2014;18(2):341–9. doi:10.1007/s11325-013-0891-7.
Benoist LB, de Ruiter MH, de Lange J, de Vries N. Residual POSA after maxillomandibular advancement in patients with severe OSA. Positional Therapy in Obstructive Sleep Apnea. Springer; 2015. p. 321–9.
van Kesteren ER, van Maanen JP, Hilgevoord AA, Laman DM, de Vries N. Quantitative effects of trunk and head position on the apnea hypopnea index in obstructive sleep apnea. Sleep. 2011;34(8):1075–81. doi:10.5665/SLEEP.1164.
Dieltjens M, Braem MJ, Vroegop AV, Wouters K, Verbraecken JA, De Backer WA, et al. Objectively measured vs self-reported compliance during oral appliance therapy for sleep-disordered breathing. Chest. 2013;144(5):1495–502. doi:10.1378/chest.13-0613.
Dieltjens M, Verbruggen AE, Braem MJ, Wouters K, Verbraecken JA, De Backer WA, et al. Determinants of objective compliance during oral appliance therapy in patients with sleep-disordered breathing: a prospective clinical trial. JAMA Otolaryngol Head Neck Surg. 2015;141(10):894–900. doi:10.1001/jamaoto.2015.1756.
Richard W, Venker J, den Herder C, Kox D, van den Berg B, Laman M, et al. Acceptance and long-term compliance of nCPAP in obstructive sleep apnea. Eur Arch Otorhinolaryngol. 2007;264(9):1081–6. doi:10.1007/s00405-007-0311-3.
Weaver TE, Grunstein RR. Adherence to continuous positive airway pressure therapy: the challenge to effective treatment. Proc Am Thorac Soc. 2008;5(2):173–8. doi:10.1513/pats.200708-119MG.
Frank MH, Ravesloot MJ, van Maanen JP, Verhagen E, de Lange J, de Vries N. Positional OSA part 1: towards a clinical classification system for position-dependent obstructive sleep apnoea. Sleep Breath. 2015;19(2):473–80. doi:10.1007/s11325-014-1022-9.
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Patty E. Vonk and Madeline J.L. Ravesloot each declare no potential conflicts of interest.
Nicolaas de Vries reports personal fees from Philips and MSD.
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Vonk, P., Ravesloot, M. & de Vries, N. Positional Therapy for Positional Obstructive Sleep Apnea: What Is New?. Curr Sleep Medicine Rep 3, 113–121 (2017). https://doi.org/10.1007/s40675-017-0081-4
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DOI: https://doi.org/10.1007/s40675-017-0081-4