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Two cases of IgA nephropathy after splenectomy: spleen as a silent culprit in the pathogenesis of IgA nephropathy

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References

  1. Wyatt RJ, Julian BA (2013) IgA nephropathy. N Engl J Med 368:2402

    Article  CAS  PubMed  Google Scholar 

  2. Song Y, Huang X, Yu G, Qiao J, Cheng J, Wu J, Chen J (2021) Pathogenesis of IgA vasculitis: an up-to-date review. Front Immunol 12:771619. https://doi.org/10.3389/fimmu.2021.771619

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  3. Morino M, Inami K, Shibuya A, Sasaki N (1994) IgA nephropathy and idiopathic thrombocytopenic purpura with splenectomy: a case report. Pediatr Nephrol 8(3):345–346. https://doi.org/10.1007/BF00866358

    Article  CAS  PubMed  Google Scholar 

  4. Stojanović V, Mitić I, Jokić R, Vucković N, Doronjski A, Vijatov G, Milosević B, Djapić M (2007) Splenic peliosis in the course of IgA nephropathy. Pediatr Nephrol 22(12):2137–2140. https://doi.org/10.1007/s00467-007-0598-8. (Epub 2007 Sep 21)

    Article  PubMed  Google Scholar 

  5. Biyikli NK, Gokce I, Cakalagaoglu F, Turkkan E, Alpay H (2010) Hereditary spherocytosis with immunoglobulin A nephropathy. Iran J Kidney Dis 4(1):78–81

    PubMed  Google Scholar 

  6. Shimamura Y, Akimoto T, Moniwa N, Hasegawa K, Ogawa Y, Takizawa H (2016) Hereditary spherocytosis presenting with immunoglobulin A nephropathy in post-splenectomy. J Gen Fam Med 17:307–310. https://doi.org/10.14442/jgfm.17.4_307

    Article  Google Scholar 

  7. Knoppova B, Reily C, Maillard N, Rizk DV, Moldoveanu Z, Mestecky J, Raska M, Renfrow MB, Julian BA, Novak J (2016) The origin and activities of IgA1-containing immune complexes in IgA nephropathy. Front Immunol 12(7):117. https://doi.org/10.3389/fimmu.2016.00117

    Article  CAS  Google Scholar 

  8. Haakenstad AO, Striker GE, Mannik M (1976) The glomerular deposition of soluble immune complexes prepared with reduced and alkylated antibodies and with intact antibodies in mice. Lab Invest 35(3):293–301

    CAS  PubMed  Google Scholar 

  9. Si M, Li L, Fang M, Ye Z, Zhang XC, Yang W, Nie L, Yu X (2023) Anomalous kinetics of galactose-deficient IgA incurring nephropathy revealed by cross-scale optical imaging. Kidney Int 103(2):320–330. https://doi.org/10.1016/j.kint.2022.08.038. (Epub 2022 Oct 28)

    Article  CAS  PubMed  Google Scholar 

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Correspondence to Ahmet Burak Dirim.

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No ethics approval was required for the case reports in our facility (Istanbul University Istanbul Faculty of Medicine Ethical Committee). The procedures followed were in accordance with the Declaration of Helsinki 1975.

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The present study complies with the guidelines for human studies.

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Informed consent was obtained from both of these patients.

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Dirim, A.B., Agargun, B.F., Hurdogan, O. et al. Two cases of IgA nephropathy after splenectomy: spleen as a silent culprit in the pathogenesis of IgA nephropathy. J Nephrol 36, 2381–2385 (2023). https://doi.org/10.1007/s40620-023-01764-z

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  • DOI: https://doi.org/10.1007/s40620-023-01764-z

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