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Mid-trimester isolated bilateral rocker bottom feet leading to prenatal diagnosis of 7q11.23 microdeletion: Williams syndrome

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Abstract

Prenatal sonographic depiction of congenital vertical talus (rocker bottom feet), describing a prominent calcaneus and rounded convex appearance of the ventral aspect of the foot, has been reported with fetal Trisomies 18, 13, 9 HOXD10 mutations and recently 2q13 microdeletion. We present a 24 year old in whom mid-trimester sonographic finding of isolated bilateral rocker bottom feet led to diagnosis of 7q11.23 microdeletion—Williams syndrome. This association has not been reported previously. This case emphasizes the critical assessment of detail microarray upon prenatal sonographic notation of abnormal structural fetal features.

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  1. The Division of Maternal-Fetal Medicine, The Department of Obstetrics and Gynecology, State University of New York (SUNY), Downstate Health Sciences University, 450 Clarkson Avenue, Box 24, Brooklyn, NY, USA

    David M. Sherer, Vicky Hsieh, Freeda Granderson, Hakeem Yusuf & Mudar Dalloul

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  1. David M. Sherer
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  2. Vicky Hsieh
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  3. Freeda Granderson
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  4. Hakeem Yusuf
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  5. Mudar Dalloul
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Correspondence to David M. Sherer.

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Sherer, D.M., Hsieh, V., Granderson, F. et al. Mid-trimester isolated bilateral rocker bottom feet leading to prenatal diagnosis of 7q11.23 microdeletion: Williams syndrome. J Ultrasound 25, 645–647 (2022). https://doi.org/10.1007/s40477-021-00638-z

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  • DOI: https://doi.org/10.1007/s40477-021-00638-z

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