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Regenerative endodontic therapy: a follow-up of 47 anterior traumatised teeth

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European Archives of Paediatric Dentistry Aims and scope Submit manuscript

Abstract

Purpose

To collect long-term survival data in anterior traumatised teeth on the outcome of Regenerative Endodontic Treatments (RET) with a network of dentists working in different clinics to overcome the problem of anecdotical evidence.

Methods

The seven dentists from Paediatric REsearch Project (PREP) performed RET treatments following the same protocol in five different secondary dental care clinics in the Netherlands. Treatment resulting in pain, apical problems, sinus tracts, resorption or fracture were considered as failure of treatment.

Results

47 teeth in 38 children were treated between January 2009 and September 2017 and had at least 6 month follow-up (mean 35 months). Apical closure was seen in 27 teeth (25 cases) and root length growth in 6 teeth (6 cases). Thickening of the root walls was seen in 20 teeth (20 cases) and obliteration of the root canal in 30 teeth (25 cases).

Of 38 teeth with apical inflammation at the start of treatment, no radiographic sign of apical inflammation was visible at 3 months in 13 of 28 teeth; taking up to 42 months for radiographic signs of apical inflammation to be not visible. Nineteen of 35 teeth showed discoloration at the beginning of treatment.

After 18 months two teeth showed signs of ankylosis, but were still functional. After 36 months one more tooth showed signs of new apical inflammation and 2 months later it was extracted.

Conclusions

With three failures in 47 treated teeth, RET seems to be a promising treatment for difficult to treat anterior traumatised teeth with an open apex.

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Acknowledgements

The authors thank Prof. DJ Manton for his critical reading and support.

Author information

Authors and Affiliations

  1. Paediatric REsearch Project (PREP), Barneveld, Nederland

    M. E. C. Elfrink, J. S. C. Heijdra, J. B. Krikken, W. H. Kouwenberg-Bruring, H. Kouwenberg, K. L. Weerheijm & J. S. J. Veerkamp

  2. Mondzorgcentrum Nijverdal, Nijverdal, The Netherlands

    M. E. C. Elfrink

  3. Tandartspraktijk Puntgaaf, Barneveld, The Netherlands

    J. S. C. Heijdra

  4. Kindermondzorgcentrum Snoet, Amsterdam, The Netherlands

    J. B. Krikken

  5. Tandartsenpraktijk Kouwenberg-Bruring, Doetinchem, The Netherlands

    W. H. Kouwenberg-Bruring & H. Kouwenberg

  6. Kindertand, Amsterdam, The Netherlands

    K. L. Weerheijm & J. S. J. Veerkamp

Authors
  1. M. E. C. Elfrink
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  2. J. S. C. Heijdra
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  3. J. B. Krikken
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  4. W. H. Kouwenberg-Bruring
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  5. H. Kouwenberg
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  6. K. L. Weerheijm
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  7. J. S. J. Veerkamp
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Contributions

All authors contributed to the study conception and design. Material preparation, data collection and analysis were performed by all authors. The first draft of the manuscript was written by MEC Elfrink and all authors commented on previous versions of the manuscript. All authors read and approved the final manuscript.

Corresponding author

Correspondence to M. E. C. Elfrink.

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Conflict of interest

There was no funding received for this study. The authors do not have a conflict of interest. All patients gave permission for the treatment and the use of their pictures.

All procedures performed in this study were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards. As our research is based on patient records and patients are not identified and do not need to do anything or anything extra in this research, ethical approval from a medical ethical committee is not required. All data used in this study are available at the corresponding author.

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Elfrink, M.E.C., Heijdra, J.S.C., Krikken, J.B. et al. Regenerative endodontic therapy: a follow-up of 47 anterior traumatised teeth. Eur Arch Paediatr Dent 22, 469–477 (2021). https://doi.org/10.1007/s40368-020-00584-0

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  • DOI: https://doi.org/10.1007/s40368-020-00584-0

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