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Innervation imaging in arrhythmia and arrhythmogenic disease

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Abstract

Cardiac innervation imaging with 123I-meta-iodobenzylguanidine scintigraphy or 11C-meta-hydroxyephedrine positron emission tomography visualizes and quantifies the activity of the sympathetic nervous system. No other imaging modality is able to stratify this potentially important trigger for various cardiac diseases. Recent literature has focussed mostly on its prognostic ability in heart failure patients, but its use is not limited to heart failure alone. In this review, the literature regarding cardiac innervation imaging in arrhythmia and arrhythmogenic syndromes is discussed, which shows potential for further study into the prognostic and diagnostic value of innervation imaging for atrial fibrillation and arrhythmogenic right ventricular cardiomyopathy especially.

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Authors and Affiliations

  1. Nuclear Medicine Department, Meander Medical Centre, Maatweg 3, 3813 TZ, Amersfoort, The Netherlands

    A. M. Scholtens

  2. Nuclear Medicine Department, Academic Medical Center, Amsterdam, The Netherlands

    H. J. Verberne

Authors
  1. A. M. Scholtens
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  2. H. J. Verberne
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Correspondence to A. M. Scholtens.

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A.M. Scholtens and H.J. Verberne declare no conflicts of interest. This article does not contain any studies with human or animal subjects performed by any of the authors.

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Scholtens, A.M., Verberne, H.J. Innervation imaging in arrhythmia and arrhythmogenic disease. Clin Transl Imaging 3, 373–378 (2015). https://doi.org/10.1007/s40336-015-0136-9

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  • DOI: https://doi.org/10.1007/s40336-015-0136-9

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