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Inter-Arm Blood Pressure Difference an Indicator of Coronary Artery Disease

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Abstract

Introduction

Considering the scarcity of the literature on the association between inter-arms blood pressure difference (IABPD) and coronary artery disease (CAD).

Aim

We performed this study to investigate the prevalence of IABPD within the Jordanian population and to assess if it has an association with CAD.

Methods

We sampled patients visiting the cardiology clinics at the Jordan University Hospital between October, 2019 and October 2021 into two groups. Participants were divided into two groups; patients with severe CAD and control group who had no evidence of CAD.

Results

We measured the blood pressure for a total of 520 patients. Of the included patients, 289 (55.6 %) had CAD while 231 (44.4%) were labeled as controls who were normal. A total of 221 (42.5%) participants had systolic IABPD above 10 mmHg, while 140 (26.9%) had a diastolic IABPD above 10 mmHg. Univariate analysis demonstrated that patients with CAD were significantly more likely to be older (p < 0.001), of the male gender (p < 0.001), hypertensive (p < 0.001), and having dyslipidemia (p < 0.001). Moreover, they had significantly higher IABPD differences in terms of both systolic and diastolic blood pressure (p < 0.001 and p = 0.022, respectively). Multivariate analysis showed that CAD was a positive predictor of abnormal systolic IABPD.

Conclusion

In our study, elevated systolic IABPD was associated with a higher prevalence of severe CAD. Patients with abnormal IABPD might be subjected to more specialist investigation as IABPD consistently predicts coronary artery disease, peripheral arterial disease or other vasculopathy throughout the literature.

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Authors and Affiliations

  1. Cardiology Section, Department of Internal Medicine, Faculty of Medicine, University of Jordan, Amman, Jordan

    Hanna K. Al-Makhamreh

  2. Department of Medicine, Al-Emadi Hospital, 50000, Doha, Qatar

    Abdulhak A. Sadalla

  3. Nephrology Section, Department of Internal Medicine, Faculty of Medicine, University of Jordan, Amman, Jordan

    Hussein Alhawari

  4. Al-Essra Hospital, Amman, 11941, Jordan

    Adees W. Bedros

  5. Al-Bashir Hospital, Amman, 11151, Jordan

    Maher M. Kahlous

  6. Department of Internal Medicine, Hamad Medical Corporation, Doha, 3050, Qatar

    Mohammed A. Amer

  7. Faculty of Medicine, School of Medicine, The University of Jordan, Amman, 11942, Jordan

    Adees W. Bedros, Maher M. Kahlous, Mohammed A. Amer, Baraa A. Al-Mubarak, Moaiad Hussein, Ahmad A. Toubasi & Hayder T. Chichan

Authors
  1. Hanna K. Al-Makhamreh
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  2. Abdulhak A. Sadalla
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  3. Hussein Alhawari
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  7. Baraa A. Al-Mubarak
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  8. Moaiad Hussein
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  9. Ahmad A. Toubasi
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Corresponding author

Correspondence to Ahmad A. Toubasi.

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Funding

The author(s) received no financial support for the research, authorship, and/or publication of this article.

Conflict of Interest

None.

Ethical Approval

The Institutional Review Board (IRB) at the University of Jordan has reviewed and approved the conductance of this study.

Informed Consent Statement

An informed consent was obtained from all the participants.

Data Availability

The data associated with this manuscript is available from the corresponding author upon reasonable request.

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Al-Makhamreh, H.K., Sadalla, A.A., Alhawari, H. et al. Inter-Arm Blood Pressure Difference an Indicator of Coronary Artery Disease. High Blood Press Cardiovasc Prev 30, 377–383 (2023). https://doi.org/10.1007/s40292-023-00591-4

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  • DOI: https://doi.org/10.1007/s40292-023-00591-4

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