References
Kolkhir P, Muñoz M, Asero R, Ferrer M, Kocatürk E, Metz M, et al. Autoimmune chronic spontaneous urticaria. J Allergy Clin Immunol. 2022;149(6):1819–31. https://doi.org/10.1016/j.jaci.2022.04.010. (PMID: 35667749).
Bedolla-Barajas M, Morales-Romero J, Hernández-Colín DD, Larenas-Linnemann D, Mariscal-Castro J, Flores-Razo MM, et al. Beyond eosinophilia: inflammatory patterns in patients with asthma. J Asthma. 2022;59(2):255–63. https://doi.org/10.1080/02770903.2020.1852413. (Epub 2020 Dec 7 PMID: 33203290).
Altrichter S, Frischbutter S, Fok JS, Kolkhir P, Jiao Q, Skov PS, et al. The role of eosinophils in chronic spontaneous urticaria. J Allergy Clin Immunol. 2020;145(6):1510–6. https://doi.org/10.1016/j.jaci.2020.03.005. (Epub 2020 Mar 26 PMID: 32224275).
Kolkhir P, Church MK, Altrichter S, Skov PS, Hawro T, Frischbutter S, et al. Eosinopenia, in chronic spontaneous urticaria, is associated with high disease activity, autoimmunity, and poor response to treatment. J Allergy Clin Immunol Pract. 2020;8(1):318-25.e5. https://doi.org/10.1016/j.jaip.2019.08.025. (Epub 2019 Aug 28 PMID: 31472293).
Grant JA, Alam R, Lett-Brown MA. Histamine-releasing factors and inhibitors: historical perspectives and possible implications in human illness. J Allergy Clin Immunol. 1991;88(5):683–93. https://doi.org/10.1016/0091-6749(91)90170-s. (PMID: 1720148).
Tharp MD. Chronic urticaria: pathophysiology and treatment approaches. J Allergy Clin Immunol. 1996;98(6 Pt 3):S325–30. https://doi.org/10.1016/S0091-6749(96)80118-7.
Takimoto-Ito R, Ma N, Kishimoto I, Kabashima K, Kambe N. The potential role of basophils in urticaria. Front Immunol. 2022;13:883692. https://doi.org/10.3389/fimmu.2022.883692. (PMID: 35663949; PMCID: PMC9157385).
Acknowledgements
Special thanks to Amit-Shira Baybev for statistical guidance.
Author information
Authors and Affiliations
Corresponding author
Ethics declarations
Funding
No funding was received for this study.
Conflict of interest
Sarah Weissmann, Nitzan Burrack, Amit Shira Babyev, Michal Gordon, Inbal Golan-Tripto, and Amir Horev have no conflicts of interest that are directly relevant to the content of this article.
Ethics approval
This study protocol was reviewed and approved by the local Ethics Committee of Soroka University Medical Center, approval number [0434-15-SOR].
Consent to participate
This study has been granted an exemption from requiring informed written consent according to the Ethics Committee of Soroka University Medical Center, approval number [0434-15-SOR].
Consent for publication
Not applicable.
Availability of data and material
Data and code are available on request because of privacy or other restrictions. For requests, please contact the corresponding author, Sarah Weissmann.
Code availability
Not applicable.
Authors’ contributions
AH and SW participated in the design of the study. SW and NB performed the statistical analysis. SW drafted the manuscript. AH and IG-T edited the manuscript. All authors read and approved the final manuscript.
Supplementary Information
Below is the link to the electronic supplementary material.
Rights and permissions
About this article
Cite this article
Weissmann, S., Burrack, N., Babyev, A.S. et al. Eosinophil–Lymphocyte Ratio, Eosinophil–Neutrophil Ratio, and Eosinophil–Monocyte Ratio in Chronic and Severe Urticaria. Am J Clin Dermatol 24, 669–671 (2023). https://doi.org/10.1007/s40257-023-00781-9
Accepted:
Published:
Issue Date:
DOI: https://doi.org/10.1007/s40257-023-00781-9