Skip to main content
Log in

Eosinophil–Lymphocyte Ratio, Eosinophil–Neutrophil Ratio, and Eosinophil–Monocyte Ratio in Chronic and Severe Urticaria

  • RESEARCH LETTER
  • Published:
American Journal of Clinical Dermatology Aims and scope Submit manuscript

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

References

  1. Kolkhir P, Muñoz M, Asero R, Ferrer M, Kocatürk E, Metz M, et al. Autoimmune chronic spontaneous urticaria. J Allergy Clin Immunol. 2022;149(6):1819–31. https://doi.org/10.1016/j.jaci.2022.04.010. (PMID: 35667749).

    Article  CAS  PubMed  Google Scholar 

  2. Bedolla-Barajas M, Morales-Romero J, Hernández-Colín DD, Larenas-Linnemann D, Mariscal-Castro J, Flores-Razo MM, et al. Beyond eosinophilia: inflammatory patterns in patients with asthma. J Asthma. 2022;59(2):255–63. https://doi.org/10.1080/02770903.2020.1852413. (Epub 2020 Dec 7 PMID: 33203290).

    Article  CAS  PubMed  Google Scholar 

  3. Altrichter S, Frischbutter S, Fok JS, Kolkhir P, Jiao Q, Skov PS, et al. The role of eosinophils in chronic spontaneous urticaria. J Allergy Clin Immunol. 2020;145(6):1510–6. https://doi.org/10.1016/j.jaci.2020.03.005. (Epub 2020 Mar 26 PMID: 32224275).

    Article  CAS  PubMed  Google Scholar 

  4. Kolkhir P, Church MK, Altrichter S, Skov PS, Hawro T, Frischbutter S, et al. Eosinopenia, in chronic spontaneous urticaria, is associated with high disease activity, autoimmunity, and poor response to treatment. J Allergy Clin Immunol Pract. 2020;8(1):318-25.e5. https://doi.org/10.1016/j.jaip.2019.08.025. (Epub 2019 Aug 28 PMID: 31472293).

    Article  PubMed  Google Scholar 

  5. Grant JA, Alam R, Lett-Brown MA. Histamine-releasing factors and inhibitors: historical perspectives and possible implications in human illness. J Allergy Clin Immunol. 1991;88(5):683–93. https://doi.org/10.1016/0091-6749(91)90170-s. (PMID: 1720148).

    Article  CAS  PubMed  Google Scholar 

  6. Tharp MD. Chronic urticaria: pathophysiology and treatment approaches. J Allergy Clin Immunol. 1996;98(6 Pt 3):S325–30. https://doi.org/10.1016/S0091-6749(96)80118-7.

    Article  CAS  PubMed  Google Scholar 

  7. Takimoto-Ito R, Ma N, Kishimoto I, Kabashima K, Kambe N. The potential role of basophils in urticaria. Front Immunol. 2022;13:883692. https://doi.org/10.3389/fimmu.2022.883692. (PMID: 35663949; PMCID: PMC9157385).

    Article  CAS  PubMed  PubMed Central  Google Scholar 

Download references

Acknowledgements

Special thanks to Amit-Shira Baybev for statistical guidance.

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Sarah Weissmann.

Ethics declarations

Funding

No funding was received for this study.

Conflict of interest

Sarah Weissmann, Nitzan Burrack, Amit Shira Babyev, Michal Gordon, Inbal Golan-Tripto, and Amir Horev have no conflicts of interest that are directly relevant to the content of this article.

Ethics approval

This study protocol was reviewed and approved by the local Ethics Committee of Soroka University Medical Center, approval number [0434-15-SOR].

Consent to participate

This study has been granted an exemption from requiring informed written consent according to the Ethics Committee of Soroka University Medical Center, approval number [0434-15-SOR].

Consent for publication

Not applicable.

Availability of data and material

Data and code are available on request because of privacy or other restrictions. For requests, please contact the corresponding author, Sarah Weissmann.

Code availability

Not applicable.

Authors’ contributions

AH and SW participated in the design of the study. SW and NB performed the statistical analysis. SW drafted the manuscript. AH and IG-T edited the manuscript. All authors read and approved the final manuscript.

Supplementary Information

Below is the link to the electronic supplementary material.

Supplementary file1 (PDF 211 kb)

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Weissmann, S., Burrack, N., Babyev, A.S. et al. Eosinophil–Lymphocyte Ratio, Eosinophil–Neutrophil Ratio, and Eosinophil–Monocyte Ratio in Chronic and Severe Urticaria. Am J Clin Dermatol 24, 669–671 (2023). https://doi.org/10.1007/s40257-023-00781-9

Download citation

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s40257-023-00781-9

Navigation