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Recent Advances of Pure Organic Room Temperature Phosphorescence Materials for Bioimaging Applications

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Chemical Research in Chinese Universities Aims and scope

Abstract

Bioimaging, as a powerful and helpful tool, which allows people to investigate deeply within living organisms, has contributed a lot for both clinical theranostics and scientific research. Pure organic room temperature phosphorescence(RTP) materials with the unique features of ultralong luminescence lifetime and large Stokes shift, can efficiently avoid biological autofluorescence and scattered light through a time-resolved imaging modality, and thus are attracting increasing attention. This review classifies pure organic RTP materials into three categories, including small molecule RTP materials, polymer RTP materials and supramolecular RTP materials, and summarizes the recent advances of pure organic RTP materials for bioimaging applications.

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References

  1. Kuno S., Akeno H., Ohtani H., Yuasa H., Phys. Chem. Chem. Phys., 2015, 17(24), 15989

    Article  CAS  Google Scholar 

  2. Smith B. R., Gambhir S. S., Chem. Rev., 2017, 117(3), 901

    Article  CAS  Google Scholar 

  3. Xu S., Chen R. F., Zheng C., Huang W., Adv. Mater., 2016, 28(45), 9920

    Article  CAS  Google Scholar 

  4. Hirata S., Totani K., Zhang J. X., Yamashita T., Kaji H., Marder S. R., Watanabe T., Adachi C., Adv. Funct. Mater., 2013, 23(27), 3386

    Article  CAS  Google Scholar 

  5. Yang J., Zhen X., Wang B., Gao X., Ren Z., Wang J., Xie Y., Li J., Peng Q., Pu K., Li Z., Nat. Commun., 2018, 9(1), 840

    Article  Google Scholar 

  6. Xu J. J., Takai A., Kobayashi Y., Takeuchi M., Chem. Commun., 2013, 49(76), 8447

    Article  CAS  Google Scholar 

  7. You Y. Q., Huang K. W., Liu X. J., Pan X., Zhi J. H., He Q. J., Shi H. F., An Z. F., Ma X., Huang W., Small, 2020, 16(8), 1906733

    Article  CAS  Google Scholar 

  8. Ma X., Xu C., Wang J., Tian H., Angew. Chem. Int. Ed., 2018, 57(34), 10854

    Article  CAS  Google Scholar 

  9. Tao Y., Chen R., Li H., Yuan J., Wan Y., Jiang H., Chen C., Si Y., Zheng C., Yang B., Xing G., Huang W., Adv. Mater., 2018, 30(44), 1803856

    Article  Google Scholar 

  10. Wang S., Yuan W. Z., Zhang Y., ACS Symp. Ser., 2016, 2, 1

    CAS  Google Scholar 

  11. Xiao L., Wu Y. S., Chen J. W., Yu Z. Y., Liu Y. P., Yao J. N., Fu H. B., J. Phys. Chem. A, 2017, 121(45), 8652

    Article  CAS  Google Scholar 

  12. Yang X. G., Yan D. P., Chem. Sci., 2016, 7(7), 4519

    Article  CAS  Google Scholar 

  13. Yuan W. Z., Shen X. Y., Zhao H., Lam J. W. Y., Tang L., Lu P., Wang C. L., Liu Y., Wang Z. M., Zheng Q., Sun J. Z., Ma Y. G., Tang B. Z., J. Phys. Chem. C, 2010, 114(13), 6091

    Article  Google Scholar 

  14. Zhi J. H., Zhou Q., Shi H. F., An Z. F., Huang W., Chem. Aslan. J., 2020, 15(7), 947

    Article  CAS  Google Scholar 

  15. Mieno H., Kabe R., Adachi C., Commun. Chem., 2018, 1(27), 1

    CAS  Google Scholar 

  16. Zhen X., Tao Y., An Z., Chen P., Xu C., Chen R., Huang W., Pu K., Adv. Mater., 2017, 29(33), 1606665

    Article  Google Scholar 

  17. Fateminia S. M. A., Mao Z., Xu S., Yang Z., Chi Z., Liu B., Angew. Chem. Int. Ed. Engl., 2017, 56(40), 12160

    Article  CAS  Google Scholar 

  18. He Z., Gao H., Zhang S., Zheng S., Wang Y., Zhao Z., Ding D., Yang B., Zhang Y., Yuan W. Z., Adv. Mater., 2019, 31(18), 1807222

    Article  Google Scholar 

  19. Zhang T., Gao H., Lv A., Wang Z., Gong Y., Ding D., Ma H., Zhang Y., Yuan W. Z., J. Mater. Chem. C, 2019, 7(29), 9095

    Article  CAS  Google Scholar 

  20. Cai S., Shi H., Li J., Gu L., Ni Y., Cheng Z., Wang S., Xiong W. W., Li L., An Z., Huang W., Adv. Mater., 2017, 29(35), 9095

    Article  Google Scholar 

  21. Shi H. F., Zou L., Huang K. W., Wang H., Sun C., Wang S., Ma H. L., He Y. R., Wang J. P., Yu H. D., Yao W., An Z. F., Zhao Q., Huang W., ACS Appl. Mater. Inter., 2019, 11(20), 18103

    Article  CAS  Google Scholar 

  22. Wang X. F., Xiao H. Y., Chen P. Z., Yang Q. Z., Chen B., Tung C. H., Chen Y. Z., Wu L. Z., J. Am. Chem. Soc., 2019, 141(12), 5045

    Article  CAS  Google Scholar 

  23. Yang J., Gao H., Wang Y., Yu Y., Gong Y., Fang M., Ding D., Hu W., Tang B. Z., Li Z., Mater. Chem. Front., 2019, 3(7), 1391

    Article  CAS  Google Scholar 

  24. Nicol A., Kwok R. T. K., Chen C., Zhao W., Chen M., Qu J., Tang B. Z., J. Am. Chem. Soc., 2017, 139(41), 14792

    Article  CAS  Google Scholar 

  25. Chen X., Xu C., Wang T., Zhou C., Du J., Wang Z., Xu H., Xie T., Bi G., Jiang J., Zhang X., Demas J. N., Trindle C. O., Luo Y., Zhang G., Angew. Chem. Int. Ed., 2016, 55(34), 9872

    Article  CAS  Google Scholar 

  26. Zhang G., Palmer G. M., Dewhirst M. W., Fraser C. L., Nat. Mater., 2009, 8(9), 747

    Article  CAS  Google Scholar 

  27. Wang T., Su X. G., Zhang X. P., Huang W. H., Huang L. K., Zhang X. Y., Sun X., Luo Y., Zhang G. Q., J. Mater. Chem. C, 2019, 7(32), 9917

    Article  CAS  Google Scholar 

  28. Chen X. H., Liu X. D., Lei J. L., Xu L., Zhao Z. H., Kausar F., Xie X. Y., Zhu X. Y., Zhang Y. M., Yuan W. Z., Mol. Syst. Des. Eng., 2018, 3(2), 364

    Article  CAS  Google Scholar 

  29. Zhou Q., Wang Z. Y., Dou X. Y., Wang Y. Z., Liu S. E., Zhang Y. M., Yuan W. Z., Mater. Chem. Front., 2019, 3(2), 257

    Article  CAS  Google Scholar 

  30. Ni X. L., Xiao X., Cong H., Zhu Q. J., Xue S. F., Tao Z., Acc. Chem. Res., 2014, 47(4), 1386

    Article  CAS  Google Scholar 

  31. Wang H., Ji X., Li Z., Huang F., Adv. Mater., 2017, 29(14), 1606117

    Article  Google Scholar 

  32. Wang J., Huang Z., Ma X., Tian H., Angew. Chem. Int. Ed., 2020, 59(25), 9928

    Article  CAS  Google Scholar 

  33. Wang J., Gu X., Ma H., Peng Q., Huang X., Zheng X., Sung S. H. P., Shan G., Lam J. W. Y., Shuai Z., Tang B. Z., Nat. Commun., 2018, 9(1), 2963

    Article  Google Scholar 

  34. Wang J., Gu X., Zhang P., Huang X., Zheng X., Chen M., Feng H., Kwok R. T. K., Lam J. W. Y., Tang B. Z., J. Am. Chem. Soc., 2017, 139(46), 16974

    Article  CAS  Google Scholar 

Download references

Acknowledgements

This work was supported by the National Natural Science Foundation of China(Nos.21871060, 21864020), the Grassland Talent Program of Inner Mongolia Autonomous Region of China, the Natural Science Foundation of Inner Mongolia Autonomous Region of China(Nos.2020JQ02, 2020MS02004) and the Natural Science Foundation of Jiangxi Province of China(No.20192BCBL23013).

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Correspondence to Ren Sha or Jianguo Wang.

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All data generated or analyzed during this study are included in this published article and its supplementary information files.

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The authors declare no conflicts of interest.

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Hou, Y., Jiang, G., Gong, J. et al. Recent Advances of Pure Organic Room Temperature Phosphorescence Materials for Bioimaging Applications. Chem. Res. Chin. Univ. 37, 73–82 (2021). https://doi.org/10.1007/s40242-021-0396-z

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  • DOI: https://doi.org/10.1007/s40242-021-0396-z

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