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Metabolic syndrome and its association with changes in modifiable risk factors: Epifloripa aging study

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Abstract

Purpose

To estimate the prevalence of Metabolic Syndrome (MetS) and its association with changes in modifiable risk factors in older adults from southern Brazil.

Methods

A longitudinal study was performed with data from EpiFloripa Aging study. We defined MetS by the existence of three or more of the following risk factors for cardiovascular disease (CVD): waist circumference (WC) (≥ 92 cm in men and ≥ 87 cm in women); fasting glucose (≥100 mg/dl); decreased HDL cholesterol (<40 mg/dl in men and <50 mg/dl in women); hypertriglyceridemia (≥150 mg/dl) and blood pressure (≥130/85 mmHg). We evaluated the changes in modifiable risk factors (smoking, alcohol consumption, fruit and vegetable consumption, physical activity, and body mass index) between the two moments of the study (2009/10 and 2013/14). Directed acyclic graph and logistic regression models were used.

Results

Among the 599 participants, the prevalence of MetS was 64.0% (95% CI, 58.7–68.9). In the adjusted analysis, those who remained or became persons who are overweight (OR = 4.59; 95% CI: 3.05–6.89) and those who remained or became insufficiently active (OR = 1.92; 95% CI: 1.23–2.98) were more likely to present MetS.

Conclusion

Our findings suggest that being or becoming overweight and being or becoming insufficiently active are modifiable factors associated with MetS. These results highlight the need for developing preventive strategies for the observed risk indicators to mitigate the prevalence of MetS in older adults.

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Acknowledgments

We would like to thank the Florianopolis Health Authority staff for their useful help with the practical aspects of the study.

Funding

This work was supported by the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), process number 475.904/2013–3. Garcia K.C. received a master’s scholarship grant from the Coordenação de Aperfeiçoamento de Pessoal de Ensino Superior (Capes) - Finance Code 001.

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Authors and Affiliations

  1. Postgraduate Program in Physical Education, Universidade Federal de Santa Catarina (UFSC), Florianópolis, SC, Brazil

    Karyne C. Garcia

  2. Center for Biological and Health Sciences, Universidade Federal do Maranhão (UFMA), São Luís, MA, Brazil

    Susana C. Confortin

  3. Universidade de São Paulo (USP), São Paulo, SP, Brazil

    Vandrize Meneghini

  4. School of Health Sciences, Universidade Federal de Santa Catarina (UFSC), Campus Trindade, Florianópolis, SC, Brazil

    Eleonora d’Orsi

  5. School of Sports, Universidade Federal de Santa Catarina (UFSC), Florianópolis, SC, Brazil

    Aline Rodrigues Barbosa

  6. Centro de Desportos/Universidade Federal de Santa Catarina, Campus Reitor João David Ferreira Lima, s/n, Trindade 88040, Florianópolis, Santa Catarina, –900, Brazil

    Aline Rodrigues Barbosa

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  1. Karyne C. Garcia
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  2. Susana C. Confortin
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Correspondence to Aline Rodrigues Barbosa.

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Garcia, K.C., Confortin, S.C., Meneghini, V. et al. Metabolic syndrome and its association with changes in modifiable risk factors: Epifloripa aging study. J Diabetes Metab Disord 21, 77–84 (2022). https://doi.org/10.1007/s40200-021-00937-6

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  • DOI: https://doi.org/10.1007/s40200-021-00937-6

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