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Autoimmune Retinopathy, Testing, and Its Controversies

  • Retina (R Goldhardt, Section Editor)
  • Published:
Current Ophthalmology Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

The purpose of this revision is to sumarize the most important clinical features of the autoimune retinopathies (AIRs).

Recent Findings

AIRs are a group of inflammatory conditions affecting the retina characterized by progressive unexplained visual loss, abnormalities and contraction in visual fields, photoreceptor and electroretinographic dysfunction, and the presence of circulating anti-retinal antibodies. The pathogenesis of AIR remains unclear and various antiretinal antibodies have been associated to the disease. The diagnosis of AIR is based on a particular clinical presentation along with the detection of serum antiretinal antibodies. Numerous anti-inflammatory therapeutic alternatives have been described for the treatment of AIR; nevertheless, there is no consensus on treatment protocol.

Summary

Because of its association with different types of malignant tumors, the early diagnosis, multi-disciplinary approach, and prompt treatment should be warranted.

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Author information

Authors and Affiliations

  1. Department of Ophthalmology and Visual Sciences, Federal University of São Paulo-UNIFESP/EPM, São Paulo, Brazil

    Luiz Roisman & Julia Dutra Rossetto

  2. Department of Ophthalmology, Hospital Federal da Lagoa, Rio de Janeiro, Brazil

    Luiz Roisman

  3. Instituto de Puericultura E Pediatria Martagão Gesteira, Centro de Ciências da Saúde, Federal University of Rio de Janeiro, Rio de Janeiro, Brazil

    Julia Dutra Rossetto

  4. Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, FL, USA

    Raquel Goldhardt

Authors
  1. Luiz Roisman
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  2. Julia Dutra Rossetto
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  3. Raquel Goldhardt
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Correspondence to Luiz Roisman.

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Conflict of Interest

Luiz Roisman and Julia Dutra Rossetto each declare no potential conflicts of interest.

Raquel Goldhardt is a Section Editor for Current Ophthalmology Reports.

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This article is part of the Topical Collection on Retina

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Roisman, L., Rossetto, J.D. & Goldhardt, R. Autoimmune Retinopathy, Testing, and Its Controversies. Curr Ophthalmol Rep 9, 178–183 (2021). https://doi.org/10.1007/s40135-021-00276-y

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  • DOI: https://doi.org/10.1007/s40135-021-00276-y

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