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Topography-Guided Ablations: Early US Experience and Utility Across the Refractive Landscape

  • Refractive Surgery: From Laser to Intraocular Lenses (C Starr, Section Editor)
  • Published:
Current Ophthalmology Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

This paper evaluated topography-guided excimer ablations and recent US experience of this technology. Personal clinical experience, initial approval of the technique, and its application to a potential extended spectrum of clinical conditions was reviewed.

Recent Findings

Topography-guided ablation can precisely treat corneas with variable topographic indices and attempt to neutralize irregularities by combining myopic and hyperopic ablation profiles. The T-CAT Phase III study demonstrated the safety and efficacy of this technique, which earned FDA approval in 2013. Current literature has reinforced its efficacy and explored off-label investigations, such as its use to improve visual results in abnormal corneas (e.g., keratoconus, post-LASIK ectasia).

Summary

Topography-guided ablation provides increased quality of vision without necessitating excess tissue removal in otherwise normal, keratoconic, ectatic, or post-corneal transplant eyes. In the future, we will likely see a combination of treatment strategies, enabling ophthalmologists to treat the entire refractive surface and refine these already remarkable results.

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Papers of particular interest, published recently, have been highlighted as: • Of Importance

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Authors and Affiliations

  1. Ophthalmic Consultants of Long, Island, Suite 160, 711 Stewart Avenue, Garden City, New York, 11530, USA

    Alanna Nattis, Marguerite McDonald & Eric D. Donnenfeld

  2. New York Medical College, Valhalla, New York, 10595, USA

    Eric Rosenberg

Authors
  1. Alanna Nattis
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  2. Eric Rosenberg
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  3. Marguerite McDonald
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  4. Eric D. Donnenfeld
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Correspondence to Alanna Nattis.

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Conflict of Interest

None of the contributing authors have any conflicts of interest in relation to thepublication of this article.

Human and Animal Rights and Informed Consent

All reported studies/experiments with human or animal subjects performed by the authors have been previously published and complied with all applicable ethical standards (including the Helsinki declaration and its amendments, institutional/national research committee standards, and international/national/institutional guidelines.

Additional information

This article is part of the Topical Collection on Refractive Surgery: From Laser to Intraocular Lenses

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Nattis, A., Rosenberg, E., McDonald, M. et al. Topography-Guided Ablations: Early US Experience and Utility Across the Refractive Landscape. Curr Ophthalmol Rep 5, 232–238 (2017). https://doi.org/10.1007/s40135-017-0145-0

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  • DOI: https://doi.org/10.1007/s40135-017-0145-0

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