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Genomic Sequencing for Infants and Children in Intensive Care Units

  • Intensive Care Medicine (E Cheung and T Connors, Section Editors)
  • Published:
Current Pediatrics Reports Aims and scope Submit manuscript

Abstract

Purpose of Review

We highlight the evolving clinical application of genomic sequencing in caring for critically ill infants and children in the intensive care unit.

Recent Findings

As turnaround times for genetic sequencing continue to decrease, the application of this technology in caring for critically ill infants and children has correspondingly increased. Not only are clinicians now using genetic sequencing to make formal diagnoses in medically complex patients, but they are also using this information to inform recommendations regarding potential treatments and anticipate patient outcomes. Importantly, its application not only stands to impact clinical care, but may also streamline health care utilization.

Summary

Genomic sequencing is a powerful technology with clear clinical application in the neonatal and pediatric ICU settings. In addition to aiding in the diagnostic evaluation of critically ill children with suspected monogenic disorders, it has a clear impact on clinical decision-making and can improve family-centered care.

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References

Papers of particular interest, published recently, have been highlighted as: • Of importance •• Of major importance

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Authors and Affiliations

  1. Division of Pediatric Critical Care Medicine, Department of Pediatrics, Morgan Stanley Children’s Hospital of New York-Presbyterian, Columbia University, College of Physicians & Surgeons, 3959 Broadway, New York, NY, 10032, USA

    Abigail S. Carey

  2. Division of Molecular Genetics, Department of Pediatrics, Morgan Stanley Children’s Hospital of New York-Presbyterian, Columbia University, College of Physicians & Surgeons, 3959 Broadway, New York, NY, 10032, USA

    Wendy K. Chung

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  1. Abigail S. Carey
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  2. Wendy K. Chung
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Correspondence to Abigail S. Carey.

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This article is part of the Topical Collection on Intensive Care Medicine

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Carey, A.S., Chung, W.K. Genomic Sequencing for Infants and Children in Intensive Care Units. Curr Pediatr Rep 7, 78–82 (2019). https://doi.org/10.1007/s40124-019-00196-3

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  • DOI: https://doi.org/10.1007/s40124-019-00196-3

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