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Biocompatible Scaffold Based on Silk Fibroin for Tissue Engineering Applications

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Abstract

Silk fibroin (SF) is a protein with unique properties that make it an ideal scaffold for tissue engineering. Research in this area has improved its advantages by incorporating many other materials during synthetic stages and helping in use of (SF) in broader biomedical application. Silk is gaining popularity as an encouraging bio-sourced raw material due to superior mechanical qualities, flexibility, as well as bioactivity. This review focus on the current advances in silk-founded biologically inspired active and efficient scaffold in medical fields as well as the most recent applications and advancements in the use of SF as a biocompatible material. The authors begun with a short overview of silk, including its origins, characteristics, source, in addition procedures. The findings of this analysis are crucial in aiding designers in making proper design structure as well as the percentage of porosity required in scaffold for the cell’s growth prior to fabrication of the scaffold. Furthermore, SF can be formed into numerous scaffold kinds such as sponges, mats, hydrogels, and films using both traditional and innovative bio-fabrication methodologies.

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    Ali Imran Ansari & Nazir Ahmad Sheikh

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Ansari, A.I., Sheikh, N.A. Biocompatible Scaffold Based on Silk Fibroin for Tissue Engineering Applications. J. Inst. Eng. India Ser. C 104, 201–217 (2023). https://doi.org/10.1007/s40032-022-00891-z

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