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Haemophilus influenzae endocarditis: a case report and literature review

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Abstract

Introduction

Haemophilus influenzae (HI) is an exceedingly rare cause of infective endocarditis (IE).

Case Presentation/Methods

We present a case of a 90-year-old female diagnosed with HI-IE involving the native tricuspid valve in the absence of traditional risk factors for right-sided endocarditis. She was treated with a 5-week course of IV Ampicillin from negative cultures and suffered no complications. We also conducted a thorough literature review through PubMed and Google Scholar, which yielded a mere 15 reported cases of HI-IE.

Results

Fourteen of the reported HI-IE cases included epidemiological data, showing no gender predominance. The mean age of the subjects was 39.5, with the mitral valve being the most implicated (64%) and tricuspid valve involvement being rare (21%).

Conclusion

Native tricuspid valve IE is an uncommon entity, especially in the absence of IV drug use. Haemophilus influenzae is an extremely rare cause of IE, with a literature review showing merely 15 reported cases. This article cites the 16th case of HI-IE published in the literature.

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Data availability

The data presented in this article is available upon request from the corresponding author. The patient data is not publicly available due to privacy reasons.

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Funding

No funding was received for this case report.

Author information

Authors and Affiliations

  1. Internal Medicine, Greater Baltimore Medical Center, Towson, MD, USA

    Nadim Jaafar, Akshay Duddu & Siddartha Guru

  2. Infectious Diseases, Greater Baltimore Medical Center, Towson, MD, USA

    Ibukunolupo Oni

Authors
  1. Nadim Jaafar
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  2. Akshay Duddu
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  3. Siddartha Guru
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  4. Ibukunolupo Oni
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Contributions

N.J., performed the literature review, prepared the figures and tables, contributed to the main manuscript. A.D. performed the literature review, contributed to the main manuscript. S.G. identified the case, performed the literature review, contributed to the main manuscript. I.O identified the case, contributed to the main manuscript, and supervised the case report. All authors have reviewed and approved the manuscript.

Corresponding author

Correspondence to Nadim Jaafar.

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The authors report there are no competing interests to declare.

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Informed consent to participate in this case report was obtained by the authors.

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Informed consent to publish this case report was obtained by the authors.

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Jaafar, N., Duddu, A., Guru, S. et al. Haemophilus influenzae endocarditis: a case report and literature review. Infection (2024). https://doi.org/10.1007/s15010-024-02219-8

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  • DOI: https://doi.org/10.1007/s15010-024-02219-8

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