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Clinical and microbiological characteristics of adult invasive Haemophilus influenzae infections: results of a 14-year single-center experience from Hungary

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Abstract

To describe the characteristics of adult invasive H. influenzae disease, 34 patients diagnosed at a single tertiary center between 2004 and 2017 were analyzed in a retrospective case series study. The annual estimated incidence was 0.1 cases/100.000 inhabitants. Dominant source of infection was pneumonia accompanied by sepsis (62%) and caused by nontypeable strains (74%) with low ampicillin resistance (14%). Survival (94%) and complication rates were high (35%). Main empirical treatments were ceftriaxone or levofloxacine.

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Acknowledgements

BGSz received the EFOP-3.6.3-VEKOP-16-2017-00009 doctorate grant as PhD student of EO. The funding source had no involvement in the preparation, writing, interpretation, or submission of the article. The study itself did not receive any external funding.

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Authors and Affiliations

  1. Department of Infectious Diseases, Saint Ladislaus Campus, South Pest Central Hospital, National Institute of Hematology and Infectious Diseases, Albert Florian ut 5-7, Budapest, 1097, Hungary

    Balint Gergely Szabo & Katalin Szidonia Lenart

  2. Faculty of Medicine, Infectious Disease Specialist Training, Semmelweis University, Ulloi ut 26, Budapest, 1085, Hungary

    Balint Gergely Szabo & Katalin Szidonia Lenart

  3. School of PhD Studies, Doctoral School of Clinical Medicine, Semmelweis University, Ulloi ut 26, Budapest, 1085, Hungary

    Balint Gergely Szabo

  4. National Public Health Institute, Albert Florian ut 2-6, Budapest, 1097, Hungary

    Tamas Tirczka

  5. Institute of Medical Microbiology, Semmelweis University, Nagyvarad ter 4, Budapest, 1098, Hungary

    Eszter Ostorhazi

Authors
  1. Balint Gergely Szabo
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  2. Katalin Szidonia Lenart
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  3. Tamas Tirczka
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  4. Eszter Ostorhazi
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Corresponding author

Correspondence to Balint Gergely Szabo.

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The authors declare no conflicts of interest regarding this study.

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Szabo, B.G., Lenart, K.S., Tirczka, T. et al. Clinical and microbiological characteristics of adult invasive Haemophilus influenzae infections: results of a 14-year single-center experience from Hungary. Infection 46, 855–860 (2018). https://doi.org/10.1007/s15010-018-1213-6

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  • DOI: https://doi.org/10.1007/s15010-018-1213-6

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