Abstract
Risk assessment analysis related to groundwater contamination by heavy metals was performed in the Shiraz city (Iran). We compared the traditional deterministic methodologies with a probabilistic approach based on the concentration of different heavy metals determined from many sampling points. The relationships between the variables by the multivariate statistical analysis were assessed, and the target hazard quotient (THQ) was calculated in children, women, and men groups. Results showed that analyzed water samples were suitable for drinking, although alkaline. Concentrations of the heavy metals were: Zn > Ni > Cu > Se > Co > Sb. The THQ values for non-carcinogenic elements showed no significant risk for population of studied age groups, although a higher THQ value was observed for the water from the northwest and some central areas of city. Mean values of cancer risk for Ni were 1.77 × 10–5, 4.36 × 10–5, and 3.32 × 10–5 in children, women, and men, respectively. The multivariate approach indicated that the carcinogenic risk certainty level was 97.6, 91.2, and 94.3% for children, women, and men, respectively, and the model sensitivity analysis showed that the most effective parameter for carcinogenicity was Ni concentration. The probabilistic analysis also showed the relative influence of geogenic and anthropogenic processes on the quality of the water of Shiraz city. We concluded that risk assessment using a probabilistic approach could be better predictive of chronic exposure to hazardous elements in drinking water, which possibility the implementation of better protective measures than the current deterministic approaches.
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References
Abedi Sarvestani R, Aghasi M (2019) Health risk assessment of heavy metals exposure (lead, cadmium, and copper) through drinking water consumption in Kerman city, Iran. Environ Earth Sci 78:714
Abolfazli D, Abbasi F, Baghapour MA, Samaei MR, Tabatabaeei HR (2021) Hazardous exposure of children with heavy metal in a southwestern city of Iran. Int J Environ Anal Chem, pp 1–13.
Adams S, Titus R, Pietersen K, Tredoux G, Harris C (2001) Hydrochemical characteristics of aquifers near Sutherland in the Western Karoo, South Africa. J Hydrol 241:91–103
Adhikari S, Yanuar E, Ng D-Q (2021) Widespread nickel contamination in drinking water supplies of elementary schools in Taichung, Taiwan. Environ Sci Pollut Res, pp 1–9.
Aleem M, Shun C, Li C, Aslam A, Yang W, Nawaz M, Ahmed W, Buttar N (2018) Evaluation of groundwater quality in the vicinity of Khurrianwala industrial zone. Pakistan Water 10:1321
Badeenezhad A, Radfard M, Abbasi F, Jurado A, Bozorginia M, Jalili M, Soleimani H (2021) Effect of land use changes on non-carcinogenic health risks due to nitrate exposure to drinking groundwater. Environ Sci Pollut Res 28:41937–41947
Barakat A, El Baghdadi M, Rais J, Aghezzaf B, Slassi M (2016) Assessment of spatial and seasonal water quality variation of Oum Er Rbia River (Morocco) using multivariate statistical techniques. Int Soil Water Conserv Res 4:284–292
Bazeli J, Ghalehaskar S, Morovati, M, Soleimani H, Masoumi S, Rahmani Sani A, Saghi MH, Rastegar A (2020) Health risk assessment techniques to evaluate non-carcinogenic human health risk due to fluoride, nitrite and nitrate using Monte Carlo simulation and sensitivity analysis in Groundwater of Khaf County, Iran. Int J Environ Anal Chem, pp 1–21.
Bortey-Sam N, Nakayama SMM, Ikenaka Y, Akoto O, Baidoo E, Mizukawa H, Ishizuka M (2015) Health risk assessment of heavy metals and metalloid in drinking water from communities near gold mines in Tarkwa. Ghana Environ Monit Assess 187:397
Epa A (1989) Risk assessment guidance for superfund. Volume I: human health evaluation manual (part a). EPA/540/1–89/002.
Fallahzadeh RA, Ghaneian MT, Miri M, Dashti MM (2017) Spatial analysis and health risk assessment of heavy metals concentration in drinking water resources. Environ Sci Pollut Res 24:24790–24802
Fallahzadeh RA, Miri M, Taghavi M, Gholizadeh A, Anbarani R, Hosseini-Bandegharaei A, Ferrante M, Oliveri Conti G (2018) Spatial variation and probabilistic risk assessment of exposure to fluoride in drinking water. Food Chem Toxicol 113:314–321
Farokhneshat F, Mahvi A, Jamali Y (2016) Carcinogenic and non-carcinogenic risk assessment of chromium in drinking water sources: Birjand, Iran. Res J Environ Toxicol 10:166–171
Fitzpatrick J, Schoeny R, Gallagher K, Deener K, Dockins C, Firestone M, Jordan W, Mcdonough M, Murphy D, Olsen M (2017) US Environmental Protection Agency’s framework for human health risk assessment to inform decision making. Int J Risk Assess Manage 20:3–20
Gebeyehu HR, Bayissa LD (2020) Levels of heavy metals in soil and vegetables and associated health risks in Mojo area. Ethiopia Plos One 15:e0227883
Harvey P, Handley H, Taylor M (2016) Widespread copper and lead contamination of household drinking water, New South Wales, Australia. Environ Res 151:275–285
Jamshidi A, Morovati M, Golbini Mofrad MM, Panahandeh M, Soleimani H, Abdolahpour Alamdari H (2021) Water quality evaluation and non-cariogenic risk assessment of exposure to nitrate in groundwater resources of Kamyaran, Iran: spatial distribution, Monte-Carlo simulation, and sensitivity analysis. J Environ Health Sci Eng 19:1117–1131
Joodavi A, Aghlmand R, Podgorski J, Dehbandi R, Abbasi A (2021) Characterization, geostatistical modeling and health risk assessment of potentially toxic elements in groundwater resources of northeastern Iran. J Hydrol Regional Stud 37:100885
Karamia L, Alimohammadia M, Soleimania H, Askaria M (2019) Assessment of water quality changes during climate change using the GIS software in a plain in the southwest of Tehran province, Iran. Desalination Water Treatment 148:119–127
Karunanidhi D, Aravinthasamy P, Subramani T, Muthusankar G (2021) Revealing drinking water quality issues and possible health risks based on water quality index (WQI) method in the Shanmuganadhi River basin of South India. Environ Geochem Health 43:931–948.
Keshavarzi B, Tazarvi Z, Rajabzadeh MA, Najmeddin A (2015) Chemical speciation, human health risk assessment and pollution level of selected heavy metals in urban street dust of Shiraz. Iran Atmos Environ 119:1–10
Kiani A, Sharafi K, Omer AK, Matin BK, Davoodi R, Mansouri B, Sharafi H, Soleimani H, Massahi T, Ahmadi E (2022) Accumulation and human health risk assessment of nitrate in vegetables irrigated with different irrigation water sources-transfer evaluation of nitrate from soil to vegetables. Environ Res 205:112527
Moghtaderi T, Alamdar R, Rodríguez-Seijo A, Naghibi SJ, Kumar V (2020) Ecological risk assessment and source apportionment of heavy metal contamination in urban soils in Shiraz, Southwest Iran. Arab J Geosci 13:1–12
Mohammadi AA, Yousefi M, Yaseri M, Jalilzadeh M, Mahvi AH (2017) Skeletal fluorosis in relation to drinking water in rural areas of West Azerbaijan, Iran. Sci Reports 7:1–7
Mosaferi M, Pourakbar M, Shakerkhatibi M, Fatehifar E, Belvasi M (2014) Quality modeling of drinking groundwater using GIS in rural communities, northwest of Iran. J Environ Health Sci Eng 12:99
Nasir MFM, Samsudin MS, Mohamad I, Awaluddin MRA, Mansor MA, Juahir H, Ramli N (2011) River water quality modeling using combined principle component analysis (PCA) and multiple linear regressions (MLR): a case study at Klang River, Malaysia. World Appl Sci J 14:73–82
Ogamba EN, Charles EE, Izah SC (2021) Distributions, pollution evaluation and health risk of selected heavy metal in surface water of Taylor creek, Bayelsa State, Nigeria. Toxicol Environ Heal Sci 13:109–121
Organization WH (1996) Trace elements in human nutrition and health, World Health Organization.
Qishlaqi A, Moore F (2007) Statistical analysis of accumulation and sources of heavy metals occurrence in agricultural soils of Khoshk River Banks, Shiraz, Iran. Am Eurasian J Agric Environ Sci 2(5):565–573
Raza M, Hussain F, Lee J-Y, Shakoor MB, Kwon KD (2017) Groundwater status in Pakistan: a review of contamination, health risks, and potential needs. Crit Rev Environ Sci Technol 47:1713–1762
Rivera-Velasquez MF, Fallico C, Guerra I, Straface S (2013) A Comparison of deterministic and probabilistic approaches for assessing risks from contaminated aquifers: an Italian case study. Waste Manage Res 31:1245–1254
Shafiuddin Ahmed AS, Hossain MB, Babu SMOF, Rahman MM, Sarker MSI (2021) Human health risk assessment of heavy metals in water from the subtropical river, Gomti, Bangladesh. Environ Nanotechnol Monit Manage 15:100416
Shahsavani S, Mohammadpour A, Shooshtarian MR, Soleimani H, Ghalhari MR, Badeenezhad A, Baboli Z, Morovati R, Javanmardi P (2023) An ontology-based study on water quality: probabilistic risk assessment of exposure to fluoride and nitrate in Shiraz drinking water, Iran using fuzzy multi-criteria group decision-making models. Environ Monit Assess 195:1–14
Shalyari N, Alinejad A, Hashemi AHG, Radfard M, Dehghani M (2019) Health risk assessment of nitrate in groundwater resources of Iranshahr using Monte Carlo simulation and geographic information system (GIS). MethodsX 6:1812–1821
Sharafi K, Mansouri B, Omer AK, Bashardoust P, Ebrahimzadeh G, Sharifi S, Massahi T, Soleimani H (2022) Investigation of health risk assessment and the effect of various irrigation water on the accumulation of toxic metals in the most widely consumed vegetables in Iran. Sci Rep 12:1–12
Sharafi K, Yunesian M, Nodehi RN, Mahvi AH, Pirsaheb M, Nazmara S (2019) The reduction of toxic metals of various rice types by different preparation and cooking processes–Human health risk assessment in Tehran households. Iran Food Chem 280:294–302
Silvestri L, Forcina A, Di Bona G, Silvestri C (2021) Circular economy strategy of reusing olive mill wastewater in the ceramic industry: How the plant location can benefit environmental and economic performance. J Clean Prod 326:129388
Soleimani H, Azhdarpoor A, Hashemi H, Radfard M, Nasri O, Ghoochani M, Azizi H, Ebrahimzadeh G, Mahvi AH (2020a) Probabilistic and deterministic approaches to estimation of non-carcinogenic human health risk due to heavy metals in groundwater resources of torbat heydariyeh, southeastern of Iran. Int J Environ Anal Chem, 1–15.
Soleimani H, Azhdarpoor A, Hashemi H, Radfard M, Nasri O, Ghoochani M, Azizi H, Ebrahimzadeh G, Mahvi AH (2022) Probabilistic and deterministic approaches to estimation of non-carcinogenic human health risk due to heavy metals in groundwater resources of torbat heydariyeh, southeastern of Iran. Int J Environ Anal Chem 102:2536–2550
Soleimani H, Nasri O, Ghoochani M, Azhdarpoor A, Dehghani M, Radfard M, Darvishmotevalli M, Oskoei V, Heydari M (2020b) Groundwater quality evaluation and risk assessment of nitrate using monte carlo simulation and sensitivity analysis in rural areas of Divandarreh County, Kurdistan province, Iran. Int J Environ Anal Chem, pp 1–19.
Tomlinson MS, Bommarito P, George A, Yelton S, Cable P, Coyte R, Karr J, Vengosh A, Gray KM, Fry RC (2019) Assessment of inorganic contamination of private wells and demonstration of effective filter-based reduction: a pilot-study in Stokes County. North Carolina Environ Res 177:108618
Wang Y, Zhu G, Engel B, Wu Y (2020) Probabilistic human health risk assessment of arsenic under uncertainty in drinking water sources in Jiangsu Province, China. Environ Geochem Health 42:2023–2037
Wu B, Zhao DY, Jia HY, Zhang Y, Zhang XX, Cheng SP (2009) Preliminary risk assessment of trace metal pollution in surface water from Yangtze River in Nanjing Section, China. Bull Environ Contam Toxicol 82:405–409
Acknowledgements
The authors would like to thank Dr. Paolo Carletti for improving the use of English in the manuscript. This research was supported by the Shiraz University of Medical Sciences (23048), and the authors would like to thank the Vice-Chancellor for Research of Shiraz University of Medical Sciences for their financial support.
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This research was funded by Shiraz University of Medical Sciences (Grant Number 23048).
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AM contributed to data collection, funding acquisition, conceptualization, investigation, writing, reviewing. MM-J contributed to conceptualization, investigation, writing, writing the original draft. HS contributed to validation, visualization methodology, reviewing, and editing. RD contributed to validation, visualization, software, writing the original draft. ZED contributed to visualization, writing, reviewing, and editing. MRS contributed to investigation, data collection, methodology, conceptualization, supervision validation. ZD contributed to conceptualization, investigation, writing, reviewing. GR contributed to investigation, validation, visualization, software. AHM contributed to investigation, visualization, project administration, conceptualization, supervision validation, visualization, resources.
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Mohammadpour, A., Motamed-Jahromi, M., Soleimani, H. et al. Trace elements human health risk assessment by Monte Carlo probabilistic method in drinking water of Shiraz, Iran. Int. J. Environ. Sci. Technol. 20, 3775–3788 (2023). https://doi.org/10.1007/s13762-023-04815-x
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DOI: https://doi.org/10.1007/s13762-023-04815-x