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Hybrid coagulation/ozonation treatment of pharmaceutical wastewater using ferric chloride, polyaluminum chloride and ozone

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Abstract

In recent years, concerns about the occurrence and fate of active pharmaceutical ingredients, solvents, intermediates and raw materials that could be present in pharmaceutical industry effluents have gained increasing attention. Conventional treatment methods, such as activated sludge, are not sufficient enough to remove active pharmaceutical ingredients completely. As a result, complementary treatment methods like coagulation and flocculation are often used and play a critical role in industrial and municipal wastewater treatment. The primary goal of these methods is to destabilize and remove colloidal particles along with other organic/inorganic contaminants. Recently empirical works have considered ozone as the most promising oxidant for the removal of micro-pollutants. The current study examined the effectiveness of coagulation/flocculation process using ferric chloride, polyaluminum chloride, and aluminum sulfate as a reasonable approach to tackle the issue of treating pharmaceutical wastewater. In addition, the results were compared with the process using only ferric chloride that was the coagulant of an actual treatment plant. Then, improvement of the process performance was investigated using ozone as an oxidant. In conclusion, it was found out that polyaluminum chloride presented better performance among two other coagulants and also adding 200 mg/L of polyaluminum chloride can lead to 97–98 % turbidity removal efficiency. Moreover, polyaluminum chloride was capable of reducing most of the environmental parameters such as chemical oxygen demand and total dissolved solid with the removal efficiency of 70 and 68 %, respectively. Additionally, ozonation improved the coagulation process, especially iron ion removal, and dramatically decreased the concentration from 5.68 to 0.19 mg/L.

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References

  • Am Water Works Res F, Langlais B, Reckhow DA, Brink DR (1991) Ozone in water treatment: application and engineering. CRC Press, Boca Raton

    Google Scholar 

  • Amuda O, Amoo I (2007) Coagulation/flocculation process and sludge conditioning in beverage industrial wastewater treatment. J Hazard Mater 141:778–783

    Article  CAS  Google Scholar 

  • Ayguna A, Yilmazb T (2010) Improvement of coagulation-flocculation process for treatment of detergent wastewaters using coagulant aids. Int J 1:97–101

    Google Scholar 

  • Ayyildiz O, Ileri B, Sanik S (2009) Impacts of water organic load on chlorine dioxide disinfection efficacy. J Hazard Mater 168:1092–1097

    Article  CAS  Google Scholar 

  • Baig S, Liechti P (2001) Ozone treatment for biorefractory COD removal. Water Sci Technol 43:197–204

    CAS  Google Scholar 

  • Errais E, Duplay J, Darragi F (2010) Textile dye removal by natural clay—case study of Fouchana Tunisian clay. Environ Technol 31:373–380

    Article  CAS  Google Scholar 

  • García Montaño J, Torrades I Carné F, Peral Pérez J (2007) Combination of advanced oxidation processes and biological treatments for commercial reactive azo dyes removal. Universitat Autònoma de Barcelona, Bellaterra

    Google Scholar 

  • Gebbie P (2001) Using polyaluminium coagulants in water treatment. In: Proceedings of 64th AWIEO Conference, 5–6 September, Australia, pp 39–47

  • Golbaz S, Jafari AJ, Rafiee M, Kalantary RR (2014) Separate and simultaneous removal of phenol, chromium, and cyanide from aqueous solution by coagulation/precipitation: mechanisms and theory. Chem Eng J 253:251–257

    Article  CAS  Google Scholar 

  • Hansen KMS, Andersen HR, Ledin A (2010) Ozonation of estrogenic chemicals in biologically treated sewage. Water Sci Technol 62:649–657

    Article  CAS  Google Scholar 

  • Huber MM, Canonica S, Park G-Y, von Gunten U (2003) Oxidation of pharmaceuticals during ozonation and advanced oxidation processes. Environ Sci Technol 37:1016–1024

    Article  CAS  Google Scholar 

  • Kushwaha JP, Srivastava VC, Mall ID (2010) Treatment of dairy wastewater by inorganic coagulants: parametric and disposal studies. Water Res 44:5867–5874

    Article  CAS  Google Scholar 

  • Lau Y-Y, Wong Y-S, Teng T-T, Morad N, Rafatullah M, Ong S-A (2014) Coagulation-flocculation of azo dye Acid Orange 7 with green refined laterite soil. Chem Eng J 246:383–390

    Article  CAS  Google Scholar 

  • Lau Y-Y, Wong Y-S, Teng T-T, Morad N, Rafatullah M, Ong S-A (2015) Degradation of cationic and anionic dyes in coagulation–flocculation process using bi-functionalized silica hybrid with aluminum-ferric as auxiliary agent. RSC Adv 5:34206–34215

    Article  CAS  Google Scholar 

  • Lee Y, von Gunten U (2010) Oxidative transformation of micropollutants during municipal wastewater treatment: comparison of kinetic aspects of selective (chlorine, chlorine dioxide, ferrate VI, and ozone) and non-selective oxidants (hydroxyl radical). Water Res 44:555–566

    Article  CAS  Google Scholar 

  • Li F, Jiang J-Q, Wu S, Zhang B (2010) Preparation and performance of a high purity poly-aluminum chloride. Chem Eng J 156:64–69

    Article  CAS  Google Scholar 

  • Liang C-Z, Sun S-P, Li F-Y, Ong Y-K, Chung T-S (2014) Treatment of highly concentrated wastewater containing multiple synthetic dyes by a combined process of coagulation/flocculation and nanofiltration. J Membr Sci 469:306–315

    Article  CAS  Google Scholar 

  • Ng WJ (2006) Industrial wastewater treatment. Imperial College Press, London

    Book  Google Scholar 

  • Papić S, Koprivanac N, Božić AL (2000) Removal of reactive dyes from wastewater using Fe(III) coagulant. Color Technol 116:352–358

    Article  Google Scholar 

  • Pontius FW, Clark SW (1999) Drinking water quality standards, regulations and goals. AWWA, Water Quality and Treatment, New York 5

    Google Scholar 

  • Soya K, Mihara N, Kuchar D, Kubota M, Matsuda H, Fukuta T (2010) Selective sulfidation of copper, zinc and nickel in plating wastewater using calcium sulfide. Int J Civil Environ Eng 2:93–97

    Google Scholar 

  • Stumm-Zollinger E, Gordon MF (1965) Biodegradation of steroid hormones. Water Pollut Control Fed 37:1506–1510

    CAS  Google Scholar 

  • Ternes TA, Joss A (2006) Human pharmaceuticals, hormones and fragrances: the challenge of micropollutants in urban water management. IWA Publishing, London, UK

  • Ternes TA, Stüber J, Herrmann N, McDowell D, Ried A, Kampmann M, Teiser B (2003) Ozonation: a tool for removal of pharmaceuticals, contrast media and musk fragrances from wastewater? Water Res 37:1976–1982

    Article  CAS  Google Scholar 

  • Tzoupanos N, Zouboulis A (2008) Coagulation-flocculation processes in water/wastewater treatment: the application of new generation of chemical reagents. In: Proceedings of 6th IASME/WSEAS international conference on heat transfer, thermal engineering and environment (HTE'08), 20–22 August, Rhodes, Greece, pp 309–317

  • Verma AK, Dash RR, Bhunia P (2012) A review on chemical coagulation/flocculation technologies for removal of colour from textile wastewaters. J Environ Manag 93:154–168

    Article  CAS  Google Scholar 

  • Yeap KL, Teng TT, Poh BT, Morad N, Lee KE (2014) Preparation and characterization of coagulation/flocculation behavior of a novel inorganic–organic hybrid polymer for reactive and disperse dyes removal. Chem Eng J 243:305–314

    Article  CAS  Google Scholar 

  • Zahrim A, Hilal N (2013) Treatment of highly concentrated dye solution by coagulation/flocculation—sand filtration and nanofiltration. Water Res Ind 3:23–34

    Article  Google Scholar 

Download references

Acknowledgments

The authors would like to thank Ferdowsi University of Mashhad for the full financial support of this study.

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Authors and Affiliations

  1. Chemical Engineering Department, Faculty of Engineering, Ferdowsi University of Mashhad, Mashhad, Iran

    A. Shirafkan, S. M. Nowee & M. M. Etemadi

  2. Chemistry Department, Faculty of Sciences, Ferdowsi University of Mashhad, Mashhad, Iran

    N. Ramezanian

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  1. A. Shirafkan
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  2. S. M. Nowee
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  3. N. Ramezanian
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  4. M. M. Etemadi
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Correspondence to S. M. Nowee.

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Shirafkan, A., Nowee, S.M., Ramezanian, N. et al. Hybrid coagulation/ozonation treatment of pharmaceutical wastewater using ferric chloride, polyaluminum chloride and ozone. Int. J. Environ. Sci. Technol. 13, 1443–1452 (2016). https://doi.org/10.1007/s13762-016-0965-8

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  • DOI: https://doi.org/10.1007/s13762-016-0965-8

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