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Drug-naïve Egyptian females with migraine are more prone to sexual dysfunction than those with tension-type headache: a cross-sectional comparative study

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Abstract

Headache is one of the chronic disorders that can trigger sexual dysfunction due to complex mechanisms. This study recruited 120 consecutive patients from our outpatient clinics with migraine (n = 60), TTH (n = 60) as well as healthy age-matched controls (n = 60) for a total of 180 patients. All the participants were evaluated by the Arabic version of the female sexual function index (ArFSFI: 19 items), the abridged 5-item version of the international index of erectile function (IIEF-5), hospital anxiety and depression scale (HADS: 14 items), visual analog scale (VAS) score, and the headache impact test questionnaire (HIT-6TM: 6 items). A significant correlation was noticed between scores of total ArFSFI in women with TTH and their partners’ IIEF-5 scores (r = 0.773, p < 0.001). In contrast, significant negative correlations were also found between scores of total ArFSFI in women with migraine(r − 0.327, p 0.011), HADS-A scores (r − 0.504, p < 0.001), HADS-D scores (r − 0.579, p < 0.001), HITS scores (r − 0.413, p 0.001), VAS scores (r 0.737, p < 0.001), and their partners’ IIEF-5 scores (r − 0.839, p < 0.001). Interestingly, our study had shown a bidirectional relation between SD, anxiety, and depression subscales of HADS in females with migraine only (28.49 ± 9.46, 13.54 ± 4.44, 15.17 ± 7.73 respectively, p 0.009), while females with migraine and SD reported statistical higher scores of anxiety and depression (25.21 ± 11.70, 12.71 ± 4.20, 17.95 ± 8.05, respectively, p 0.006). This study had demonstrated that drug-naïve Egyptian females with migraine are more prone to SD than those with TTH.

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This research did not receive any specific grant from funding agencies in the public, commercial, or not-for-profit sectors.

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Authors and Affiliations

  1. Andrology and STDs Department, Kasr Al-Ainy Faculty of Medicine, Cairo University, Al-Saray Street, El Manial, Cairo, 11956, Egypt

    Hossam El Din Hosni Ahmed & Sameh Fayek GamalEl Din

  2. Neurology Department, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt

    Mohammed Ibrahim Oraby

  3. Ministry of Health and Population, Giza, Egypt

    Heba Mohammad Abd Elhameed

  4. Andrology and STDs Department, Faculty of Medicine, Beni-Suef University, Beni-Suef, Egypt

    Ahmed Ragab Ahmed

Authors
  1. Hossam El Din Hosni Ahmed
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  2. Sameh Fayek GamalEl Din
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  3. Mohammed Ibrahim Oraby
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  4. Heba Mohammad Abd Elhameed
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  5. Ahmed Ragab Ahmed
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Correspondence to Sameh Fayek GamalEl Din.

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All procedures performed were in accordance with the ethical standards of the institutional and national research committee and with the 1964 Helsinki Declaration and its later amendments or comparable ethical standards. The study was approved by the local ethical committee.

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Informed consent was obtained from all individual participants included in the study.

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Ahmed, H.E.D.H., GamalEl Din, S.F., Oraby, M.I. et al. Drug-naïve Egyptian females with migraine are more prone to sexual dysfunction than those with tension-type headache: a cross-sectional comparative study. Acta Neurol Belg 121, 1745–1753 (2021). https://doi.org/10.1007/s13760-020-01504-1

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  • DOI: https://doi.org/10.1007/s13760-020-01504-1

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