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Syntheses, crystal structures and biological activities of two new drum-shaped organotin(IV) carboxylate complexes with 2-(4-alkylbenzoyl)benzoic acid (alkyl = methyl or ethyl)

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Abstract

Two new organotin(IV) carboxylate complexes, [PhSnO(L1)]6 ·4(toluene) (1) (HL1 = 2-(4-methylbenzoyl)benzoic acid) and [PhSnO(L2)]6 (2) (HL2 = 2-(4-ethylbenzoyl)benzoic acid), were synthesized by the reaction of ligand acids with mono-organotin complex in 1:1 molar ratio. The synthesized complexes have been structurally characterized by elemental analysis, IR, 1H, 13C, 119Sn NMR spectroscopy and X-ray crystallography diffraction analyses. Both 1 and 2 are hexanuclear organotin complex with drum-shaped structure. In the solid state of 1 and 2, 1D and 2D supramolecular networks are formed by hydrogen bonds, C–H···π or π···π interactions. Furthermore, the preliminary antitumor activities of 1 and 2 have been studied. The antitumor results show they exhibit good biological activities and may be explored for potential antitumor drugs.

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Acknowledgements

We acknowledged the Science and Technology department of Jilin province (No. 20120440).

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Authors and Affiliations

  1. Department of Chemistry, Northeast Normal University, Changchun, China

    Xiao Han, Min Tian, Jingwen Liang & Dongsheng Zhu

  2. Department of Pharmacy, Jilin Medical University, Jilin, China

    Xiao Xiao

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  1. Xiao Han
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  2. Min Tian
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  3. Xiao Xiao
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  4. Jingwen Liang
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Correspondence to Dongsheng Zhu.

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Han, X., Tian, M., Xiao, X. et al. Syntheses, crystal structures and biological activities of two new drum-shaped organotin(IV) carboxylate complexes with 2-(4-alkylbenzoyl)benzoic acid (alkyl = methyl or ethyl). J IRAN CHEM SOC 15, 513–519 (2018). https://doi.org/10.1007/s13738-017-1251-5

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  • DOI: https://doi.org/10.1007/s13738-017-1251-5

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