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Candida albicans and Staphylococcus lugdunensis superinfection of liver cysts in a patient with autosomal dominant polycystic kidney disease under prednisolone treatment

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Abstract

We report a case of superinfection of liver cysts caused by Candida albicans and Staphylococcus lugdunensis in a patient with autosomal dominant polycystic kidney disease. A 69-year-old man with chief complaints of headache and blurred vision was admitted to the former institution for the evaluation of suspected temporal arteritis. He was prescribed oral prednisolone (55 mg/day) as a preemptive treatment; however, he became febrile and presented with bilateral flank pain during prednisolone tapering. Blood culture revealed fungemia as a result of Candida famata infection; thus, micafungin treatment was started. Thereafter, recrudescence of the C-reactive protein level ensued. Then a cyst infection as visualized on magnetic resonance imaging led to cyst aspiration sclerotherapy. Cyst aspirate culture revealed the presence of C. albicans in one of the cysts and S. lugdunensis in two of the cysts. The patient was clinically stabilized with an additional 3 weeks of antibiotic and antifungal drug administration.

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Acknowledgements

I owe this work to my teaching doctors, colleagues, and doctors in the hospital who referred the patient in a timely manner.

Funding

This study was funded by the Okinaka Memorial Institute for Medical Research.

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Authors and Affiliations

  1. Department of Nephrology, Nephrology Center, Toranomon Hospital Kajigaya, Takatsu-ku Kajigaya 1-3-1, Kawasaki City, Kanagawa, 213-8587, Japan

    Takashi Iijima, Tatsuya Suwabe, Keita Inui, Hiroki Mizuno, Rikako Hiramatsu, Masayuki Yamanouchi, Naoki Sawa, Kenmei Takaichi & Yoshifumi Ubara

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  1. Takashi Iijima
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  2. Tatsuya Suwabe
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  3. Keita Inui
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  4. Hiroki Mizuno
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  5. Rikako Hiramatsu
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  6. Masayuki Yamanouchi
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  7. Naoki Sawa
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  8. Kenmei Takaichi
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  9. Yoshifumi Ubara
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Correspondence to Yoshifumi Ubara.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Iijima, T., Suwabe, T., Inui, K. et al. Candida albicans and Staphylococcus lugdunensis superinfection of liver cysts in a patient with autosomal dominant polycystic kidney disease under prednisolone treatment. CEN Case Rep 9, 370–374 (2020). https://doi.org/10.1007/s13730-020-00488-4

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  • DOI: https://doi.org/10.1007/s13730-020-00488-4

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