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Solitary lower limb cutaneous metastasis in a case of esophageal adenocarcinoma: a rare presentation

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Abstract

Esophageal cancer is the ninth most common cancer all over the world and is sixth in the list of cancer-related mortality. Here in this report, we present an elderly male with solitary subcutaneous metastasis to right thigh 2 years following esophagectomy for esophageal adenocarcinoma. Operative notes revealed inadequate margins on frozen section analysis during initial resection, which were subsequently revised. Postoperative histopathology showed ypT3N0M0 Grade 3 mucin-secreting adenocarcinoma. A wedge biopsy from the thigh growth revealed metastatic mucinous adenocarcinoma. Positron Emission Tomography (PET) was done, which showed a higher tracer uptake in the ulcero-proliferative lesion arising from the subcutaneous plane in the right thigh with no evidence of any other metastasis or recurrence at the primary site. As the reported incidence of distant unexpected metastases is growing, careful physical examination with a preoperative PET-CT is indispensable. Further knowledge on options on treatment of such isolated cutaneous metastasis needs to be studied by the scientific community.

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Funding

This study received no specific grant from any funding agency in the public, commercial, or not-for-profit sectors.

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Authors and Affiliations

  1. Division of GI & HPB Surgery, Department of Surgery, Jawaharlal Institute of Postgraduate Medical Education and Research, Dhanvantari Nagar, Puducherry, 605006, India

    Souradeep Dutta, Muhamed Tajudeen, Siva Ranjit Kumar Vaka, Ankit Jain, Abhinaya Reddy & Vishnu Prasad Nelamangala Ramakrishnaiah

  2. Department of Pathology, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, India

    Bheemanathi Hanuman Srinivas

Authors
  1. Souradeep Dutta
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  2. Muhamed Tajudeen
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  3. Siva Ranjit Kumar Vaka
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  4. Ankit Jain
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  5. Abhinaya Reddy
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  6. Bheemanathi Hanuman Srinivas
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  7. Vishnu Prasad Nelamangala Ramakrishnaiah
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Contributions

SD and MT performed draft preparation. SD, MT, and SRKV collected and analyzed data.: AJ, AR, VPNR, and BHS were involved in review and editing and supervision. All the authors contributed to the conceptualization and design of the case report. All the authors have read and approved the manuscript.

Corresponding author

Correspondence to Vishnu Prasad Nelamangala Ramakrishnaiah.

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The authors declare that they have no conflict of interest.

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Written informed consent was obtained from the patient for publication of this report and the accompanying images, and the patient’s anonymity was upheld.

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Dutta, S., Tajudeen, M., Vaka, S.R.K. et al. Solitary lower limb cutaneous metastasis in a case of esophageal adenocarcinoma: a rare presentation. Int Canc Conf J 11, 109–113 (2022). https://doi.org/10.1007/s13691-021-00532-9

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  • DOI: https://doi.org/10.1007/s13691-021-00532-9

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