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A rare case of hepatocellular carcinoma metastasizing hematogenously to the rectum

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Abstract

Metastasis to the gastrointestinal tract from hepatocellular carcinoma is uncommon. Herein, we report a rare case of with a metastatic lesion in the rectum, which resembled a primary rectal cancer. An 82-year-old Japanese woman, who had been diagnosed with liver cirrhosis and hepatocellular carcinoma due to chronic hepatitis C, was admitted for further examination of bloody stool. She had undergone radiofrequency ablation twice and transarterial chemoembolization twice before the admission. A colonoscopy revealed a protruding rectal tumor, which was confirmed by biopsy to be poorly differentiated adenocarcinoma. Meanwhile multiple liver recurrences were recognized by an abdominal computed tomography scan. To improve her symptoms and resume the treatment of hepatocellular carcinoma, laparoscopic anterior resection of the rectum was performed to remove the primary rectal cancer. To our surprise, detailed histological examination confirmed that the rectal tumor was a metastatic lesion from the hepatocellular carcinoma.

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Authors and Affiliations

  1. Department of Gastroenterological Surgery, Cancer Institute Hospital of Japanese Foundation for Cancer Research, 3-8-31 Ariake, Koto-ku, Tokyo, 135-8550, Japan

    Atsushi Ikeda, Satoshi Nagayama, Takashi Akiyoshi, Tsuyoshi Konishi, Yoshiya Fujimoto, Yosuke Fukunaga & Masashi Ueno

  2. Department of Pathology, Cancer Institute Hospital of Japanese Foundation for Cancer Research, Tokyo, Japan

    Noriko Yamamoto & Yuichi Ishikawa

Authors
  1. Atsushi Ikeda
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  2. Satoshi Nagayama
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  3. Noriko Yamamoto
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  4. Takashi Akiyoshi
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  5. Tsuyoshi Konishi
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  6. Yoshiya Fujimoto
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  7. Yosuke Fukunaga
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  8. Yuichi Ishikawa
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  9. Masashi Ueno
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Corresponding author

Correspondence to Atsushi Ikeda.

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The authors declare that they have no conflict of interest.

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All procedures performed in studies involving human participants were in accordance with the ethical standards of the institutional and/or national research committee and with the 1964 Helsinki declaration and its later amendments or comparable ethical standards.

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Informed consent was obtained from all individual participants included in the study.

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Ikeda, A., Nagayama, S., Yamamoto, N. et al. A rare case of hepatocellular carcinoma metastasizing hematogenously to the rectum. Int Canc Conf J 5, 168–173 (2016). https://doi.org/10.1007/s13691-016-0251-0

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  • DOI: https://doi.org/10.1007/s13691-016-0251-0

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