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Pharmacokinetic behaviour of clinically important TCM prescriptions

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Abstract

Traditional Chinese Medicine (TCM), has played a vital role in human health and welfare for a long period. Traditional Chinese Medicine prescription is the prime application scheme of TCM. Combination of two or more medicinal herbs is one of the most important and fundamental characteristic of TCM prescription. In light of their simplicity and the basic qualities of complex prescription, multi herb formulations (extract, decoction and etc) are of great significance in the considerations of herb compatibility, standardization, safety evaluation, therapeutic potential and mechanism of action of multi herb formulations. Several research papers have been published that state therapeutic activity of multi herb formulations but few are discussing the exact role of herbal combinations. To provide satisfactory data about rationality and compatibility of these TCM prescription and for pharmacokinetic profile, we reviewed the pharmacokinetic profile of 30 different clinically important TCM prescriptions.

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Acknowledgements

The authors would like to acknowledge the support from Bharati Vidyapeeth Deemed University, Poona College of Pharmacy, Pune, Maharashtra, India.

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Authors and Affiliations

  1. Cipla R & D, LBS Road, Vikhroli (W), Mumbai, Maharashtra, 400079, India

    Piyush Mehta

  2. Department of Pharmaceutical Chemistry, Bharati Vidyapeeth University, Poona College of Pharmacy, Erandwane, Pune, Maharashtra, 411 038, India

    Sathiyanarayanan Lohidasan & K. R. Mahadik

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  1. Piyush Mehta
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  2. Sathiyanarayanan Lohidasan
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  3. K. R. Mahadik
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Correspondence to Sathiyanarayanan Lohidasan.

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Mehta, P., Lohidasan, S. & Mahadik, K.R. Pharmacokinetic behaviour of clinically important TCM prescriptions. Orient Pharm Exp Med 17, 171–188 (2017). https://doi.org/10.1007/s13596-017-0281-y

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