Abstract
The precise regulation of miRNA is crucial for plant growth and fitness, which requires the presence of a core microprocessor composed of DICER-LIKE 1 (DCL1), HYPONASTIC LEAVES 1 (HYL1), and SERRATE (SE). In this commentary, we highlight the new findings showing that pre-mRNA processing 4 kinase A (PRP4KA) phosphorylates SE and promotes its degradation via the 20S proteasome to fine-tune miRNA biogenesis in Arabidopsis by controlling the accumulation of SE.
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Abbreviations
- DCL1:
-
DICER-LIKE 1
- HYL1:
-
HYPONASTIC LEAVES 1
- SE:
-
SERRATE
- PRP4KA:
-
Pre-mRNA processing 4 kinase A
- pri-miRNA:
-
Primary miRNA
- CHR2/BRM:
-
CHROMATIN REMODELING 2/BRAHMA
- NEXT:
-
NUCLEAR EXOSOME TARGETING
- ARS2:
-
ARSENIC RESISTANCE PROTEIN 2
- siRNA:
-
Small interfering RNA
- PAG1:
-
PROTEASOME ALPHA SUBUNIT G1
- PHB:
-
PHABULOSA
- SPL10:
-
SQUAMOSA PROMOTER BINDING PROTEIN-LIKE 10
- NAM:
-
NO APICAL MERISTEM
- ATAF:
-
ARABIDOPSIS THALIANA ACTIVATING FACTOR
- CUC:
-
CUP SHAPED COTYLEDON
- NAC:
-
NAM, ATAF and CUC
- MYB33:
-
MYELOBLASTOSIS 33
References
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VM designed the outline of the article, composed the manuscript and figure. BM provided scientific feedback and critical comments and revised the content. All the authors read and approved the manuscript.
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Mishra, V., Maurya, B. PRP4KA phosphorylates SERRATE and promotes its degradation to coordinate miRNA production. J. Plant Biochem. Biotechnol. 32, 417–420 (2023). https://doi.org/10.1007/s13562-023-00835-3
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DOI: https://doi.org/10.1007/s13562-023-00835-3