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Contrast-enhanced dual mode imaging: photoacoustic imaging plus more

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Abstract

Conventional biomedical imaging modalities in wide clinical use, such as ultrasound imaging, X-ray computed tomography, magnetic resonance imaging, and positron emission tomography, can provide morphological, anatomical, and functional information about biological tissues. However, single mode imaging in conventional medicine provides only limited information for definitive diagnoses. Thus, combinational diagnosis using multiple imaging modalities has become increasingly important. Recently, photoacoustic imaging (PAI) has gained significant attention, and several PAI prototypes have been used in clinical trials. At the same time, PAI has been tested in combination with conventional imaging modalities. For all these imaging modalities, various contrast-enhancing agents have been developed for various purposes. In this review article, we will focus on recent progress in developing dual mode contrast agents for PAI in combination with other conventional imaging modalities.

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Acknowledgements

This research was supported by a grant from the Korea Health Technology R&D Project through the Korea Health Industry Development Institute (KHIDI), funded by the Ministry of Health and Welfare, Republic of Korea (HI15C1817). Additional funding was received from the China-ROK (NRF-2013K1A3A1A20046921) and from the NRF Pioneer Research Center Program (NRF-2014M3C1A3017229 and NRF-2015M3C1A3056409), and from the Marine Biotechnology Program (20150220) funded by the Ministry of Oceans and Fisheries, Korea.

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  1. Future IT Innovation Laboratory, Department of Creative IT Engineering, Pohang University of Science and Technology (POSTECH), 77 Cheongam-ro, Nam-gu, Pohang, Gyeongbuk, Republic of Korea

    Sungjo Park, Unsang Jung, Seunghyun Lee, Donghyun Lee & Chulhong Kim

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  1. Sungjo Park
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Park, S., Jung, U., Lee, S. et al. Contrast-enhanced dual mode imaging: photoacoustic imaging plus more. Biomed. Eng. Lett. 7, 121–133 (2017). https://doi.org/10.1007/s13534-016-0006-z

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