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Phytochemical Profile of Rock Jasmine (Androsace foliosa Duby ex Decne) by Using HPLC and GC–MS Analyses

  • Research Article-Biological Sciences
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Abstract

Androsace foliosa, also known as rock jasmine and a member of the Primulaceae family, is an important medicinal plant with a wide range of applications such as antioxidant, antidiabetic, hepatoprotective, abortifacient, antibacterial, antifungal, anticancerous, anti-inflammatory as well as a flavor enhancer, as insecticidal, as a spice and commonly found in Pakistan. The current study was planned to identify the phytochemical constituents of A. foliosa roots and leaves extracts using high-performance liquid chromatography (HPLC) and gas chromatography/mass spectrometry (GC–MS). HPLC results showed the presence of important phenolic and flavonoids such as gallic acid, rutin and quercetin in A. foliosa leaves and roots crude methanolic extracts. GC–MS analysis of A. foliosa n-hexane leaves fraction revealed the presence of nine pharmacologically active compounds such as hydroxylamine-O-decyl, butanoic acid heptafluoro, sulfurous acid 2-propyl heptyl ester, E-15-heptadecenal, eicosane 9-cyclohexyl, (Z,E)-tetradeca-9,12-dienyl acetate, octadecyl-propane-1,3-diol, di-isobutyl phthalates, aspidofractinine-3-methanol, 17-methoxy-, acetate (ester). Besides, E-15-heptadecenal (34%) and hydroxylamine-O-decyl (30%) are major compounds occurring in A. foliosa n-hexane leaves fraction. As phytochemical constituents present in A. foliosa extracts have been identified, it could be an important medicinal plant to isolate the pharmacologically active compounds to manage different diseases and A. foliosa might play an important role in clinical science, particularly in drug development.

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Acknowledgements

We acknowledge chairman Department of Pharmacy, COMSAT Institute, Abbottabad, Pakistan. This paper was supported by the KU Research Professor Program of Konkuk University, Seoul, South Korea.

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Authors and Affiliations

  1. Department of Pharmacy, University of the Poonch Rawalakot, Rawalakot, Azad Kashmir, Pakistan

    Jawad Zaheer

  2. Institute of Pharmaceutical Sciences, COMSATS Institute of Information Technology Abbottabad, Abbottabad, Pakistan

    Qazi Najam-Us-Saqib

  3. Department of Pharmaceutical Chemistry, Riphah International University, Sector G-7/4, Islamabad, Pakistan

    Tayyaba Anwar

  4. Department of Eastern Medicine, Government College University, Faisalabad, Pakistan

    Fahad Said Khan & Muhammad Akram

  5. Department of Biochemistry, Government College University, Faisalabad, Pakistan

    Naveed Munir

  6. V.M. Gorbatov Federal Research Center for Food Systems of Russian Academy of Sciences, Moscow, Russian Federation

    Maksim Rebezov

  7. Prokhorov General Physics Institute of the Russian Academy of Science, 38 Vavilova Str, Moscow, Russian Federation, 119991

    Maksim Rebezov

  8. Department of Technology of Food Production, K.G. Razumovsky Moscow State University of Technologies and Management (the First Cossack University), Moscow, Russian Federation, 109004

    Mohammad Ali Shariati

  9. Department of Crop Science, College of Sanghuh Life Science, Konkuk University, Seoul, 05029, Republic of Korea

    Muthu Thiruvengadam

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  1. Jawad Zaheer
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Correspondence to Muhammad Akram or Muthu Thiruvengadam.

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Zaheer, J., Najam-Us-Saqib, Q., Anwar, T. et al. Phytochemical Profile of Rock Jasmine (Androsace foliosa Duby ex Decne) by Using HPLC and GC–MS Analyses. Arab J Sci Eng 46, 5385–5392 (2021). https://doi.org/10.1007/s13369-020-05241-8

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