Skip to main content

Advertisement

Log in

Herpes simplex virus-1 as a rare etiology of isolated acute cerebellitis: case report and literature review

  • Case Report
  • Published:
Journal of NeuroVirology Aims and scope Submit manuscript

Abstract

Acute cerebellitis is one of the most common cerebellar disorders and occurs due to para-infectious, post-infectious, or post-vaccination cerebellar inflammation. Herpes simplex virus-1 (HSV-1) is known as a common infectious cause of sporadic encephalitis. Cerebellar involvement of HSV-1 is rare and almost always associated with meningoencephalitis. To date, HSV-1 has been identified as the cause of acute isolated cerebellitis in only two patients. Here we report another case of isolated acute cerebellitis caused by HSV-1 in a 20-month-old boy.

This is a preview of subscription content, log in via an institution to check access.

Access this article

Price excludes VAT (USA)
Tax calculation will be finalised during checkout.

Instant access to the full article PDF.

Fig. 1

Similar content being viewed by others

References

  • Bradshaw MJ, Venkatesan A (2016) Herpes simplex virus-1 encephalitis in adults: pathophysiology, diagnosis, and management. Neurotherapeutics 13:493–508. https://doi.org/10.1007/s13311-016-0433-7

    Article  CAS  PubMed  PubMed Central  Google Scholar 

  • Ciardi M, Giacchetti G, Fedele CG, Tenorio A, Brandi A, Libertone R, Ajassa C, Borgese L, Delia S (2003) Acute cerebellitis caused by herpes simplex virus type 1. Clin Infect Dis 36:50–54

    Article  Google Scholar 

  • Connolly AM, Dodson WE, Prensky AL, Rust RS (1994) Course and outcome of acute cerebellar ataxia. Ann Neurol 35:673–679

    Article  CAS  Google Scholar 

  • De Bruecker Y, Claus F, Demaerel P, Ballaux F, Sciot R, Lagae L, Buyse G, Wilms G (2004) MRI findings in acute cerebellitis. Euro Radiol 14:1478–1483

    Article  Google Scholar 

  • Emelifeonwu JA, Shetty J, Kaliaperumal C, Gallo P, Sokol D, Soleiman H, Kandasamy J (2018) Acute cerebellitis in children: a variable clinical entity. J Child Neurol 33:675–684. https://doi.org/10.1177/0883073818777673

    Article  PubMed  Google Scholar 

  • Lancella L, Esposito S, Galli ML, Bozzola E (2017) Acute cerebellitis in children: an eleven year retrospective multicentric study in Italy. Ital J Pediatr 43:54

    Article  Google Scholar 

  • Nussinovitch M, Prais D, Volovitz B, Shapiro R, Amir J (2003) Post-infectious acute cerebellar ataxia in children. Clin Pediatr (Phila) 42:581–584

    Article  Google Scholar 

  • Rozenberg F, Deback C, Agut H (2011) Herpes simplex encephalitis: from virus to therapy. Infect Disord Drug Targets 11:235–250

    Article  CAS  Google Scholar 

  • Skelly MJ, Burger AA, Adekola O (2012) Herpes simplex virus-1 encephalitis: a review of current disease management with three case reports. Antivir Chem Chemother 23:13–18. https://doi.org/10.3851/IMP2129

    Article  CAS  PubMed  Google Scholar 

  • Tlili-Graiess K, Mhiri Souei M, Mlaiki B, Arifa N, Moulahi H, Jemni Gharbi H, Yacoub M, Essoussi M (2006) Imaging of acute cerebellitis in children. Report of 4 cases. J Neuroradiol 33:38–44

    Article  CAS  Google Scholar 

Download references

Author information

Authors and Affiliations

Authors

Corresponding author

Correspondence to Cem Paketci.

Ethics declarations

Conflict of interest

The authors declare that they have no conflict of interest.

Additional information

Publisher’s note

Springer Nature remains neutral with regard to jurisdictional claims in published maps and institutional affiliations.

Rights and permissions

Reprints and permissions

About this article

Check for updates. Verify currency and authenticity via CrossMark

Cite this article

Paketci, C., Edem, P., Okumus, C. et al. Herpes simplex virus-1 as a rare etiology of isolated acute cerebellitis: case report and literature review. J. Neurovirol. 26, 270–272 (2020). https://doi.org/10.1007/s13365-019-00802-6

Download citation

  • Received:

  • Revised:

  • Accepted:

  • Published:

  • Issue Date:

  • DOI: https://doi.org/10.1007/s13365-019-00802-6

Keywords

Navigation