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Central and peripheral nervous system involvement in Zika virus infection in a child

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Abstract

A 7-year-old boy that presented an encephalomyeloradiculitis and no classic symptoms of arboviruses. Zika virus (ZIKV) was confirmed by molecular analyses of cerebrospinal fluid and 1 year later by plaque reduction neutralization test. This case demonstrates that ZIKV can be associated with diffuse nervous system infection in children.

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Funding

The authors received financial support from the Conselho Nacional de Desenvolvimento Científico e Tecnológico (CNPq), Coordenação de Aperfeiçoamento de Pessoal de Nível Superior(CAPES), Departamento de Ciência e Tecnologia (DECIT) do Ministério da Saúde and Fundação de Amparo à Pesquisa do Estado de Minas Gerais (FAPEMIG). EGK is a fellow from CNPq.

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Author notes

  1. Paula Eillanny Silva Marinho and Pedro Paulo Martins Alvarenga contributed equally to this work.

Authors and Affiliations

  1. Laboratório de Vírus, Departamento de Microbiologia, Instituto de Ciências Biológicas, Universidade Federal de Minas Gerais, Av. Antônio Carlos 6627 Caixa, Postal 486, Belo Horizonte, MG, 31270-901, Brazil

    Paula Eillanny Silva Marinho, Mauricio Teixeira Lima, Adriana de Souza Andrade, Ana Paula Correa Crispim, Mirela Cristina Soares Gasparini & Erna Geessien Kroon

  2. Hospital Infantil João Paulo II, FHEMIG, Belo Horizonte, Minas Gerais, Brazil

    Pedro Paulo Martins Alvarenga, Talitah Michel Sanchez Candiani, Fabrizia Santos Castro, Aline Zocrato Alves de Sousa & Eisler Cristiane Carvalho Viegas

  3. Faculdade de Medicina, Universidade Federal de Minas Gerais, Belo Horizonte, Minas Gerais, Brazil

    Pedro Paulo Martins Alvarenga

  4. Faculdade de Medicina de Diamantina, Universidade Federal dos Vales do Jequitinhonha e Mucuri, Teófilo Otoni, Minas Gerais, Brazil

    Danilo Bretas de Oliveira

  5. Instituto de Ensino e Pesquisa Santa Casa de Belo Horizonte, Belo Horizonte, Minas Gerais, Brazil

    Paulo Pereira Christo

Authors
  1. Paula Eillanny Silva Marinho
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  2. Pedro Paulo Martins Alvarenga
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  3. Mauricio Teixeira Lima
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  4. Adriana de Souza Andrade
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  5. Talitah Michel Sanchez Candiani
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  6. Ana Paula Correa Crispim
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  7. Mirela Cristina Soares Gasparini
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  8. Fabrizia Santos Castro
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  9. Aline Zocrato Alves de Sousa
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  10. Eisler Cristiane Carvalho Viegas
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  11. Danilo Bretas de Oliveira
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  12. Paulo Pereira Christo
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  13. Erna Geessien Kroon
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Corresponding author

Correspondence to Erna Geessien Kroon.

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Cite this article

Marinho, P.E.S., Alvarenga, P.P.M., Lima, M.T. et al. Central and peripheral nervous system involvement in Zika virus infection in a child. J. Neurovirol. 25, 893–896 (2019). https://doi.org/10.1007/s13365-019-00770-x

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  • DOI: https://doi.org/10.1007/s13365-019-00770-x

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