Conclusions
In times of coronavirus pandemic, we must be careful in the use of aspirin as prior clustering of cases occurred during epidemics of influenza. One case of multisystem inflammatory syndrome complicated by Reye syndrome has been reported. Care must be taken to utilize aspirin only when absolutely needed. Fear of Reye syndrome should not stop us from using aspirin in conditions such as KD or ARF where its benefits significantly outweigh the risks. The new British guidelines on the management of KD do not mention Reye syndrome as a potential adverse event anywhere in the guidelines as they recognize that the beneficial effect of aspirin outweighs the risk in these conditions.
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Poddar, U., Vadlapudi, S.S. Reye Syndrome- An Enigma That Remains. Indian Pediatr 60, 486–487 (2023). https://doi.org/10.1007/s13312-023-2914-1
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DOI: https://doi.org/10.1007/s13312-023-2914-1