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Risk Factors for Catheter-Associated Urinary Tract Infections (CA-UTI) in the Pediatric Intensive Care Unit

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Abstract

Objective

To describe the occurrence, microbiology, and risk factors of catheter-associated urinary tract infections (CA-UTI) in critically ill children.

Methods

We conducted a review of hospital records for CA-UTI in the pediatric intensive care unit (PICU) over a 7-year period (2014–2020).

Results

62 CA-UTI cases (48% boys, median (IQR) age 36 (12,96 month) were identified during the study period with occurrence rate of 7.2/1000 catheter-days. The most common organisms were Escherichia coli (32.4%) and Enterococcus faecalis (30.6%). Using a multivariate logistic regression analysis, the significant associated variables for CA-UTI were duration of catheter drainage (a OR (95% CI) 1.14, (1.03,1.27), P=−0.009), PICU stay (aOR (95% CI) 1.13 (1.05,1.21) (P<0.001), and hospital stay (aOR (95% CI): 1.03 (1.01,1.06), P=0.015).

Conclusion

CA-UTI is not an uncommon nosocomial infection in PICU. The risk increases with increasing duration of catheter drainage, and hospital or PICU stay.

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Funding

Funding: None; Competing interests: None stated.

Author information

Authors and Affiliations

  1. Department of Pediatric Intensive Care, St John’s Medical College and Hospital, Bengaluru, Karnataka, 560 034, India

    A. V. Lalitha

  2. Department of Microbiology, St. John’s Medical College and Hospital, Bengaluru, Karnataka, India

    Manisha Paul & Savitha Nagraj

  3. Department of Biostatistics, St. John’s Medical College and Hospital, Bengaluru, Karnataka, India

    Santu Ghosh

Authors
  1. A. V. Lalitha
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  2. Manisha Paul
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  3. Savitha Nagraj
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  4. Santu Ghosh
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Contributions

Contributors: LAV: contributed to data collection, analysis of the data and writing of the manuscript. MP: contributed to study design, analysis of data and writing of the manuscript; SV: contributed to critical review of the manuscript; and SG: contributed to statistical analysis and review of the manuscript. All authors approved the final version of manuscript and are accountable for all aspects related to the study.

Corresponding author

Correspondence to A. V. Lalitha.

Ethics declarations

Ethics clearance: IEC, St John’s Medical College; No. 94/2019 dated March 14, 2019.

Additional information

Note: Additional material related to the study is available with the online version at https://www.indianpediatrics.net

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Lalitha, A.V., Paul, M., Nagraj, S. et al. Risk Factors for Catheter-Associated Urinary Tract Infections (CA-UTI) in the Pediatric Intensive Care Unit. Indian Pediatr 59, 613–616 (2022). https://doi.org/10.1007/s13312-022-2573-7

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  • DOI: https://doi.org/10.1007/s13312-022-2573-7

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